Annotation Detail for SORCS2
Basic Information Top
| Gene Symbol: | SORCS2 ( - ) |
|---|---|
| Gene Full Name: | sortilin-related VPS10 domain containing receptor 2 |
| Band: | 4p16.1 |
| Quick Links | Entrez ID:57537; OMIM: 606284; Uniprot ID:SORC2_HUMAN; ENSEMBL ID: ENSG00000184985; HGNC ID: 16698 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.479099
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 1 / 70761 | 14 |  |
| blastocyst | 1 / 62319 | 16 | |
| fetus | 11 / 564012 | 19 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 17 / 1939121 | 8 |  |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 1 / 17475 | 57 |  |
| breast (mammary gland) tumor | 4 / 94178 | 42 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 2 / 82823 | 24 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 4 / 263845 | 15 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 0 / 136302 | 0 | |
| kidney tumor | 3 / 68959 | 43 | |
| leukemia | 3 / 95842 | 31 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 2 / 97250 | 20 | |
| normal | 44 / 3360307 | 13 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 1 / 46356 | 21 | |
| skin tumor | 1 / 124949 | 8 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 1 / 29757 | 33 | |
| blood | 3 / 123478 | 24 | |
| bone | 2 / 71655 | 27 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 15 / 1100989 | 13 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 4 / 149255 | 26 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 4 / 215722 | 18 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 7 / 211054 | 33 | |
| heart | 1 / 89626 | 11 | |
| intestine | 0 / 234472 | 0 | |
| kidney | 4 / 211777 | 18 | |
| larynx | 0 / 24145 | 0 | |
| liver | 0 / 207743 | 0 | |
| lung | 2 / 336974 | 5 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 4 / 153271 | 26 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 1 / 107715 | 9 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 0 / 280825 | 0 | |
| prostate | 1 / 189345 | 5 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 1 / 210574 | 4 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 0 / 96619 | 0 | |
| testis | 1 / 330442 | 3 | |
| thymus | 2 / 81131 | 24 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 1 / 52413 | 19 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 1 / 232878 | 4 | |
| vascular | 0 / 51780 | 0 |
Microarray in - Probe name: CUST_14208_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 3.43 ± 1.01 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 3.29 ± 0.77 | |
| Basal Part of Pons | 2.96 ± 0.64 | |
| Cerebellar Cortex | 2.83 ± 0.73 | |
| Cerebellar Nuclei | 3.32 ± 0.89 | |
| Claustrum | 3.76 ± 0.68 | |
| Epithalamus | 2.98 ± 0.79 | |
| Frontal Lobe | 2.95 ± 0.81 | |
| Globus Pallidus | 3.82 ± 0.88 | |
| Hypothalamus | 3.29 ± 0.96 | |
| Insula | 2.79 ± 0.62 | |
| Limbic Lobe | 3.17 ± 0.88 | |
| Mesencephalon | 3.08 ± 0.74 | |
| Myelencephalon | 3.24 ± 0.99 | |
| Occipital Lobe | 3.4 ± 0.87 | |
| Parietal Lobe | 3.28 ± 0.92 | |
| Pontine Tegmentum | 3.34 ± 0.83 | |
| Striatum | 3.71 ± 0.8 | |
| Subthalamus | 3.2 ± 0.91 | |
| Temporal Lobe | 3.17 ± 0.87 | |
| Thalamus | 3.1 ± 0.77 | |
| White Matter | 4.33 ± 0.43 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Sorcs2 | CB | Cerebellum | 8.73 | |
| 14.55 | | |||
| Sorcs2 | CTX | Cerebral cortex | 29.53 | |
| 24.71 | | |||
| Sorcs2 | HIP | Hippocampal region | 25.5 | |
| 33.19 | | |||
| Sorcs2 | HPF | Hippocampal formation | 31.51 | |
| 34.57 | | |||
| Sorcs2 | HY | Hypothalamus | 6.83 | |
| 5.84 | | |||
| Sorcs2 | LSX | Lateral septal complex | 25.44 | |
| 22.19 | | |||
| Sorcs2 | MB | Midbrain | 8.59 | |
| 8.23 | | |||
| Sorcs2 | MY | Medulla | 9.35 | |
| 10.96 | | |||
| Sorcs2 | OLF | Olfactory bulb | 64.84 | |
| 61.07 | | |||
| Sorcs2 | P | Pons | 7.02 | |
| 7.3 | | |||
| Sorcs2 | PAL | Pallidum | 8.6 | |
| 8.23 | | |||
| Sorcs2 | RHP | Retrohippocampal region | 42.93 | |
| 38.14 | | |||
| Sorcs2 | sAMY | Striatum-like amygdalar nuclei | 27.48 | |
| 21.61 | | |||
| Sorcs2 | STR | Striatum | 49.7 | |
| 40.04 | | |||
| Sorcs2 | STRd | Striatum dorsal region | 65.42 | |
| 53.8 | | |||
| Sorcs2 | STRv | Striatum ventral region | 23.43 | |
| 17.36 | | |||
| Sorcs2 | TH | Thalamus | 33.68 | |
| 31.69 | |