AutismKB 2.0

Annotation Detail for WDR35


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Basic Information Top
Gene Symbol:WDR35 ( KIAA1336,MGC33196 )
Gene Full Name: WD repeat domain 35
Band: 2p24.1
Quick LinksEntrez ID:57539; OMIM: 613602; Uniprot ID:WDR35_HUMAN; ENSEMBL ID: ENSG00000118965; HGNC ID: 29250
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst5 / 6231980
fetus9 / 56401215
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult51 / 193912126
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor6 / 9417863
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor9 / 26384534
glioma1 / 1068839
head and neck tumor7 / 13630251
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal69 / 336030720
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma2 / 4635643
skin tumor4 / 12494932
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood0 / 1234780 
bone2 / 7165527
bone marrow0 / 488010 
brain14 / 110098912
cervix0 / 481710 
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue11 / 21572250
esophagus0 / 202090 
eye10 / 21105447
heart0 / 896260 
intestine5 / 23447221
kidney4 / 21177718
larynx0 / 241450 
liver0 / 2077430 
lung6 / 33697417
lymph0 / 442700 
lymph node2 / 9161021
mammary gland8 / 15327152
mouth3 / 6705244
muscle3 / 10771527
nerve1 / 1576863
ovary1 / 1020519
pancreas3 / 21481213
parathyroid5 / 20539243
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate1 / 1893455
salivary gland0 / 201550 
skin5 / 21057423
spleen1 / 5395218
stomach0 / 966190 
testis27 / 33044281
thymus2 / 8113124
thyroid4 / 4747384
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1420_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.19 ± 0.43
Basal Forebrain5.22 ± 0.3
Basal Part of Pons4.66 ± 0.7
Cerebellar Cortex4.68 ± 0.32
Cerebellar Nuclei4.66 ± 0.41
Claustrum5.02 ± 0.59
Epithalamus5.93 ± 0.68
Frontal Lobe4.86 ± 0.42
Globus Pallidus5.64 ± 0.23
Hypothalamus5.22 ± 0.4
Insula4.89 ± 0.4
Limbic Lobe5.07 ± 0.42
Mesencephalon5.16 ± 0.43
Myelencephalon5.05 ± 0.49
Occipital Lobe5.36 ± 0.41
Parietal Lobe5.1 ± 0.5
Pontine Tegmentum5.04 ± 0.45
Striatum5.45 ± 0.38
Subthalamus4.59 ± 0.22
Temporal Lobe4.93 ± 0.4
Thalamus4.98 ± 0.32
White Matter5.98 ± 0.29
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Wdr35CBCerebellum14.81
19.61
Wdr35CTXCerebral cortex51.93
39.98
Wdr35HIPHippocampal region40.65
55.47
Wdr35HPFHippocampal formation44.71
49.21
Wdr35HYHypothalamus32.97
27.2
Wdr35LSXLateral septal complex31.42
23.77
Wdr35MBMidbrain40.33
36.91
Wdr35MYMedulla42.42
46.68
Wdr35OLFOlfactory bulb45.19
36.57
Wdr35PPons36.34
38.17
Wdr35PALPallidum35.23
30.73
Wdr35RHPRetrohippocampal region51.24
41.84
Wdr35sAMYStriatum-like amygdalar nuclei45.58
32.96
Wdr35STRStriatum33.98
24.47
Wdr35STRdStriatum dorsal region29.84
21.86
Wdr35STRvStriatum ventral region44.72
29.49
Wdr35THThalamus35.88
30.76
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018