AutismKB 2.0

Annotation Detail for PTK7


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Basic Information Top
Gene Symbol:PTK7 ( CCK4 )
Gene Full Name: PTK7 protein tyrosine kinase 7
Band: 6p21.1
Quick LinksEntrez ID:5754; OMIM: 601890; Uniprot ID:PTK7_HUMAN; ENSEMBL ID: ENSG00000112655; HGNC ID: 9618
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body18 / 70761254
blastocyst20 / 62319320
fetus38 / 56401267
neonate6 / 31097192
infant1 / 2362042
juvenile1 / 5555617
adult85 / 193912143
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor1 / 3436629
chondrosarcoma2 / 8282324
colorectal tumor6 / 11424652
esophageal tumor1 / 1729057
gastrointestinal tumor5 / 11936941
germ cell tumor27 / 263845102
glioma9 / 10688384
head and neck tumor16 / 136302117
kidney tumor2 / 6895929
leukemia9 / 9584293
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal183 / 336030754
ovarian tumor9 / 76682117
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS12 / 12568095
prostate cancer3 / 10268029
retinoblastoma3 / 4635664
skin tumor1 / 1249498
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor14 / 90257155
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood3 / 12347824
bone6 / 7165583
bone marrow0 / 488010 
brain33 / 110098929
cervix1 / 4817120
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue47 / 215722217
esophagus1 / 2020949
eye13 / 21105461
heart9 / 89626100
intestine15 / 23447263
kidney7 / 21177733
larynx2 / 2414582
liver1 / 2077434
lung17 / 33697450
lymph0 / 442700 
lymph node6 / 9161065
mammary gland7 / 15327145
mouth14 / 67052208
muscle9 / 10771583
nerve0 / 157680 
ovary15 / 102051146
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta13 / 28082546
prostate3 / 18934515
salivary gland1 / 2015549
skin6 / 21057428
spleen5 / 5395292
stomach2 / 9661920
testis48 / 330442145
thymus36 / 81131443
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord2 / 13680146
uterus25 / 232878107
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 207011_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.85
Adipocyte6.5
AdrenalCortex7.45
Adrenalgland5.7
Amygdala6.55
Appendix7.75
AtrioventricularNode5.4
BDCA4+_DentriticCells28.45
Bonemarrow6.7
BronchialEpithelialCells19.4
CD105+_Endothelial6.8
CD14+_Monocytes6.75
CD19+_BCells(neg._sel.)6.5
CD33+_Myeloid7.45
CD34+11.3
CD4+_Tcells7.05
CD56+_NKCells7.45
CD71+_EarlyErythroid6
CD8+_Tcells6.45
CardiacMyocytes9.05
Caudatenucleus5.7
Cerebellum5.3
CerebellumPeduncles7.45
CiliaryGanglion4.95
CingulateCortex6.75
Colorectaladenocarcinoma13.05
DorsalRootGanglion5.5
FetalThyroid6.4
Fetalbrain6.5
Fetalliver5.75
Fetallung7.15
GlobusPallidus4.85
Heart8.95
Hypothalamus6.65
Kidney5.35
Leukemia_chronicMyelogenousK-5626.1
Leukemia_promyelocytic-HL-605.8
Leukemialymphoblastic(MOLT-4)9.1
Liver8.75
Lung7.95
Lymphnode5.5
Lymphoma_burkitts(Daudi)8.5
Lymphoma_burkitts(Raji)9.25
MedullaOblongata5.85
OccipitalLobe5.45
OlfactoryBulb5.25
Ovary4.4
Pancreas5.4
PancreaticIslet8.2
ParietalLobe7.1
Pituitary7.8
Placenta11.05
Pons6.35
PrefrontalCortex7.3
Prostate8
Salivarygland5.35
SkeletalMuscle8.6
Skin5.3
SmoothMuscle8.4
Spinalcord7
SubthalamicNucleus6
SuperiorCervicalGanglion8.35
TemporalLobe6.15
Testis6.45
TestisGermCell7.65
TestisIntersitial6.15
TestisLeydigCell7.8
TestisSeminiferousTubule6.5
Thalamus6.7
Thymus6.35
Thyroid8.35
Tongue6.5
Tonsil6.5
Trachea6.2
TrigeminalGanglion8.2
Uterus10.55
UterusCorpus12.05
WholeBlood6.7
Wholebrain4.9
colon6.8
pineal_day7.98
pineal_night7.72
retina9.95
small_intestine6.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10300_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.85 ± 0.86
Basal Forebrain3.45 ± 0.48
Basal Part of Pons3.3 ± 0.75
Cerebellar Cortex4.01 ± 0.44
Cerebellar Nuclei3.67 ± 0.55
Claustrum3.94 ± 1
Epithalamus4.73 ± 0.41
Frontal Lobe3.49 ± 0.72
Globus Pallidus3.55 ± 0.73
Hypothalamus4.34 ± 0.53
Insula3.8 ± 0.51
Limbic Lobe3.62 ± 0.82
Mesencephalon3.85 ± 0.73
Myelencephalon3.8 ± 0.78
Occipital Lobe4.36 ± 0.65
Parietal Lobe3.9 ± 0.76
Pontine Tegmentum3.84 ± 0.71
Striatum3.39 ± 0.96
Subthalamus3.23 ± 0.22
Temporal Lobe3.77 ± 0.63
Thalamus4.04 ± 0.64
White Matter3.29 ± 0.7
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ptk7CBCerebellum13
13.51
Ptk7CTXCerebral cortex25.22
17.07
Ptk7HIPHippocampal region10.91
9.9
Ptk7HPFHippocampal formation13.22
11.05
Ptk7HYHypothalamus2.26
1.66
Ptk7LSXLateral septal complex10.93
10.47
Ptk7MBMidbrain6.91
6.48
Ptk7MYMedulla13.3
13.7
Ptk7OLFOlfactory bulb15.65
11.53
Ptk7PPons7.45
8
Ptk7PALPallidum2.88
2.4
Ptk7RHPRetrohippocampal region16.54
12.24
Ptk7sAMYStriatum-like amygdalar nuclei3.36
2.15
Ptk7STRStriatum8.92
6.35
Ptk7STRdStriatum dorsal region9.35
6.51
Ptk7STRvStriatum ventral region9.05
5.96
Ptk7THThalamus4.71
3.93
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00009594 15 481 495 CMSSTPAGSIEAQAR Peptide Atlas
PTK7_HUMAN_270 7 270 276 SRPPHLR PRIDE
PTK7_HUMAN_31 17 31 47 AIVFIKQPSSQDALQGR PRIDE
PTK7_HUMAN_845 8 845 852 RELEMFGK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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