AutismKB 2.0

Annotation Detail for ZNF398


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Basic Information Top
Gene Symbol:ZNF398 ( KIAA1339,P51,P71,ZER6 )
Gene Full Name: zinc finger protein 398
Band: 7q35
Quick LinksEntrez ID:57541; OMIM: NA; Uniprot ID:ZN398_HUMAN; ENSEMBL ID: ENSG00000197024; HGNC ID: 18373
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst4 / 6231964
fetus17 / 56401230
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult48 / 193912124
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor16 / 26384560
glioma1 / 1068839
head and neck tumor3 / 13630222
kidney tumor1 / 6895914
leukemia2 / 9584220
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma2 / 7175527
non-neoplasia1 / 9725010
normal79 / 336030723
ovarian tumor6 / 7668278
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites1 / 4001524
bladder0 / 297570 
blood1 / 1234788
bone2 / 7165527
bone marrow0 / 488010 
brain19 / 110098917
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus1 / 2020949
eye8 / 21105437
heart4 / 8962644
intestine7 / 23447229
kidney6 / 21177728
larynx0 / 241450 
liver2 / 2077439
lung13 / 33697438
lymph0 / 442700 
lymph node4 / 9161043
mammary gland3 / 15327119
mouth1 / 6705214
muscle2 / 10771518
nerve0 / 157680 
ovary4 / 10205139
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta5 / 28082517
prostate7 / 18934536
salivary gland3 / 20155148
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis19 / 33044257
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus8 / 23287834
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6110_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.98 ± 0.6
Basal Forebrain3.44 ± 0.32
Basal Part of Pons3.39 ± 0.44
Cerebellar Cortex3.98 ± 0.25
Cerebellar Nuclei3.28 ± 0.56
Claustrum3.85 ± 0.64
Epithalamus3.24 ± 0.52
Frontal Lobe3.45 ± 0.57
Globus Pallidus2.99 ± 0.78
Hypothalamus3.34 ± 0.84
Insula3.41 ± 0.37
Limbic Lobe3.58 ± 0.71
Mesencephalon3.53 ± 0.64
Myelencephalon3.52 ± 0.63
Occipital Lobe3.88 ± 0.59
Parietal Lobe3.54 ± 0.63
Pontine Tegmentum3.53 ± 0.67
Striatum3.34 ± 0.56
Subthalamus3.19 ± 0.67
Temporal Lobe3.49 ± 0.62
Thalamus3.49 ± 0.54
White Matter4.39 ± 0.53
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Zfp398CBCerebellum42.34
45.31
Zfp398CTXCerebral cortex58.28
40.9
Zfp398HIPHippocampal region37.57
50.43
Zfp398HPFHippocampal formation40.14
42.4
Zfp398HYHypothalamus28.66
21.85
Zfp398LSXLateral septal complex11.23
8.64
Zfp398MBMidbrain50.65
43.51
Zfp398MYMedulla59.32
59.81
Zfp398OLFOlfactory bulb57.72
47.08
Zfp398PPons51.7
48.66
Zfp398PALPallidum31.6
25.8
Zfp398RHPRetrohippocampal region45.27
32.61
Zfp398sAMYStriatum-like amygdalar nuclei34.49
23.38
Zfp398STRStriatum25.24
17.39
Zfp398STRdStriatum dorsal region22.49
16.03
Zfp398STRvStriatum ventral region29.57
18.23
Zfp398THThalamus45.92
39.15
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018