AutismKB 2.0

Annotation Detail for TXNDC16


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Basic Information Top
Gene Symbol:TXNDC16 ( KIAA1344 )
Gene Full Name: thioredoxin domain containing 16
Band: 14q22.1
Quick LinksEntrez ID:57544; OMIM: NA; Uniprot ID:TXD16_HUMAN; ENSEMBL ID: ENSG00000087301; HGNC ID: 19965
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus15 / 56401226
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult16 / 19391218
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor6 / 26384522
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal68 / 336030720
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer1 / 1026809
retinoblastoma2 / 4635643
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone1 / 7165513
bone marrow0 / 488010 
brain24 / 110098921
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye4 / 21105418
heart2 / 8962622
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver5 / 20774324
lung4 / 33697411
lymph0 / 442700 
lymph node7 / 9161076
mammary gland3 / 15327119
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate1 / 1893455
salivary gland0 / 201550 
skin2 / 2105749
spleen1 / 5395218
stomach1 / 9661910
testis24 / 33044272
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P398836
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.88 ± 0.49
Basal Forebrain4.58 ± 0.33
Basal Part of Pons5.23 ± 0.41
Cerebellar Cortex5.13 ± 0.27
Cerebellar Nuclei4.66 ± 0.66
Claustrum4.86 ± 0.85
Epithalamus4.65 ± 0.56
Frontal Lobe5.04 ± 0.43
Globus Pallidus4.1 ± 0.58
Hypothalamus4.91 ± 0.41
Insula5.04 ± 0.38
Limbic Lobe4.81 ± 0.51
Mesencephalon4.8 ± 0.64
Myelencephalon4.91 ± 0.56
Occipital Lobe4.95 ± 0.66
Parietal Lobe4.97 ± 0.53
Pontine Tegmentum4.93 ± 0.52
Striatum4.33 ± 0.66
Subthalamus4.97 ± 0.45
Temporal Lobe5.08 ± 0.4
Thalamus5.03 ± 0.62
White Matter5.23 ± 0.22
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
5730420B22RikCBCerebellum44.38
51.77
5730420B22RikCTXCerebral cortex100
78.67
5730420B22RikHIPHippocampal region61.43
82.97
5730420B22RikHPFHippocampal formation69.45
78.37
5730420B22RikHYHypothalamus48.45
38.28
5730420B22RikLSXLateral septal complex64.72
48.24
5730420B22RikMBMidbrain59.82
53.19
5730420B22RikMYMedulla64.92
63.16
5730420B22RikOLFOlfactory bulb87.61
78.63
5730420B22RikPPons54.8
50.7
5730420B22RikPALPallidum60.69
54.99
5730420B22RikRHPRetrohippocampal region83.52
72.64
5730420B22RiksAMYStriatum-like amygdalar nuclei58.13
43.89
5730420B22RikSTRStriatum86.45
66.58
5730420B22RikSTRdStriatum dorsal region89.31
69.54
5730420B22RikSTRvStriatum ventral region100
75.13
5730420B22RikTHThalamus51.39
40.41
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018