AutismKB 2.0

Annotation Detail for MICAL3


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Basic Information Top
Gene Symbol:MICAL3 ( KIAA0819,MGC189703 )
Gene Full Name: microtubule associated monoxygenase, calponin and LIM domain containing 3
Band: 22q11.21
Quick LinksEntrez ID:57553; OMIM: 608882; Uniprot ID:MICA3_HUMAN; ENSEMBL ID: ENSG00000093100,ENSG00000243156; HGNC ID: 24694
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst2 / 6231932
fetus51 / 56401290
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult118 / 193912160
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor17 / 114246148
esophageal tumor0 / 172900 
gastrointestinal tumor45 / 119369376
germ cell tumor13 / 26384549
glioma10 / 10688393
head and neck tumor5 / 13630236
kidney tumor3 / 6895943
leukemia2 / 9584220
liver tumor3 / 9635931
lung tumor1 / 1031279
lymphoma4 / 7175555
non-neoplasia4 / 9725041
normal243 / 336030772
ovarian tumor2 / 7668226
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer5 / 10268048
retinoblastoma0 / 463560 
skin tumor8 / 12494964
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland2 / 3319760
ascites42 / 400151049
bladder1 / 2975733
blood1 / 1234788
bone3 / 7165541
bone marrow0 / 488010 
brain81 / 110098973
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye14 / 21105466
heart10 / 89626111
intestine27 / 234472115
kidney12 / 21177756
larynx2 / 2414582
liver8 / 20774338
lung29 / 33697486
lymph4 / 4427090
lymph node22 / 91610240
mammary gland3 / 15327119
mouth1 / 6705214
muscle3 / 10771527
nerve1 / 1576863
ovary2 / 10205119
pancreas10 / 21481246
parathyroid5 / 20539243
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta9 / 28082532
prostate14 / 18934573
salivary gland0 / 201550 
skin9 / 21057442
spleen5 / 5395292
stomach1 / 9661910
testis23 / 33044269
thymus2 / 8113124
thyroid1 / 4747321
tonsil2 / 16999117
trachea0 / 524130 
umbilical cord0 / 136800 
uterus11 / 23287847
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212715_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts19
Adipocyte5.65
AdrenalCortex6.2
Adrenalgland5
Amygdala18.55
Appendix6
AtrioventricularNode4.65
BDCA4+_DentriticCells5.5
Bonemarrow5.9
BronchialEpithelialCells5.75
CD105+_Endothelial5.85
CD14+_Monocytes6.15
CD19+_BCells(neg._sel.)26.4
CD33+_Myeloid7.25
CD34+7.2
CD4+_Tcells6.15
CD56+_NKCells6.4
CD71+_EarlyErythroid19.3
CD8+_Tcells5.55
CardiacMyocytes7.7
Caudatenucleus5.85
Cerebellum14.8
CerebellumPeduncles11.1
CiliaryGanglion4.2
CingulateCortex8.1
Colorectaladenocarcinoma5.85
DorsalRootGanglion4.6
FetalThyroid6.8
Fetalbrain44.4
Fetalliver5.05
Fetallung4.75
GlobusPallidus4.4
Heart8.6
Hypothalamus17.7
Kidney4.95
Leukemia_chronicMyelogenousK-5625.3
Leukemia_promyelocytic-HL-605.1
Leukemialymphoblastic(MOLT-4)4.4
Liver9.35
Lung6.35
Lymphnode5.2
Lymphoma_burkitts(Daudi)7.6
Lymphoma_burkitts(Raji)8.9
MedullaOblongata10.65
OccipitalLobe6.85
OlfactoryBulb12.7
Ovary3.9
Pancreas4.7
PancreaticIslet6.15
ParietalLobe6.2
Pituitary6.75
Placenta5.9
Pons5.6
PrefrontalCortex56.7
Prostate6.8
Salivarygland4.65
SkeletalMuscle6.85
Skin4.5
SmoothMuscle6.55
Spinalcord6.3
SubthalamicNucleus5.35
SuperiorCervicalGanglion6.7
TemporalLobe5.4
Testis5
TestisGermCell5.5
TestisIntersitial4.95
TestisLeydigCell5.8
TestisSeminiferousTubule5.6
Thalamus6.35
Thymus4.55
Thyroid13.4
Tongue5.7
Tonsil6.1
Trachea4.85
TrigeminalGanglion5.85
Uterus28.55
UterusCorpus5.25
WholeBlood5.95
Wholebrain15.4
colon5.8
pineal_day7.26
pineal_night7.3
retina11.325
small_intestine5.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P366082
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.34 ± 0.69
Basal Forebrain5.96 ± 0.3
Basal Part of Pons5.76 ± 0.51
Cerebellar Cortex6.23 ± 0.31
Cerebellar Nuclei5.34 ± 0.53
Claustrum4.98 ± 1.01
Epithalamus6.61 ± 0.91
Frontal Lobe5.53 ± 0.58
Globus Pallidus4.95 ± 0.41
Hypothalamus5.36 ± 0.68
Insula5.68 ± 0.44
Limbic Lobe5.48 ± 0.71
Mesencephalon5.56 ± 0.68
Myelencephalon5.68 ± 0.6
Occipital Lobe6.15 ± 0.54
Parietal Lobe5.59 ± 0.6
Pontine Tegmentum5.5 ± 0.68
Striatum5.14 ± 0.45
Subthalamus5.54 ± 0.64
Temporal Lobe5.79 ± 0.53
Thalamus5.64 ± 0.56
White Matter6.48 ± 0.2
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mical3CBCerebellum86.15
100
Mical3CTXCerebral cortex100
100
Mical3HIPHippocampal region68.29
100
Mical3HPFHippocampal formation88.66
100
Mical3HYHypothalamus100
98.85
Mical3LSXLateral septal complex100
99.2
Mical3MBMidbrain97.93
94.64
Mical3MYMedulla95.81
100
Mical3OLFOlfactory bulb100
100
Mical3PPons91.13
98.99
Mical3PALPallidum100
100
Mical3RHPRetrohippocampal region100
100
Mical3sAMYStriatum-like amygdalar nuclei100
100
Mical3STRStriatum100
100
Mical3STRdStriatum dorsal region100
100
Mical3STRvStriatum ventral region100
100
Mical3THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
MICA3_HUMAN_495 13 495 507 DIHLEMESLVNSR PRIDE
PAp00095328 14 31 44 AFQELCDHLELKPK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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