AutismKB 2.0

Annotation Detail for ARHGAP21


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Basic Information Top
Gene Symbol:ARHGAP21 ( ARHGAP10,DKFZp761L0424,FLJ33323,FLJ90108 )
Gene Full Name: Rho GTPase activating protein 21
Band: 10p12.1
Quick LinksEntrez ID:57584; OMIM: 609870; Uniprot ID:RHG21_HUMAN; ENSEMBL ID: ENSG00000107863; HGNC ID: 23725
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst2 / 6231932
fetus37 / 56401265
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult123 / 193912163
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor9 / 11424678
esophageal tumor0 / 172900 
gastrointestinal tumor7 / 11936958
germ cell tumor5 / 26384518
glioma8 / 10688374
head and neck tumor11 / 13630280
kidney tumor7 / 68959101
leukemia2 / 9584220
liver tumor3 / 9635931
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal189 / 336030756
ovarian tumor0 / 766820 
pancreatic tumor8 / 10461676
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer6 / 10268058
retinoblastoma1 / 4635621
skin tumor5 / 12494940
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland3 / 3319790
ascites3 / 4001574
bladder2 / 2975767
blood1 / 1234788
bone4 / 7165555
bone marrow10 / 48801204
brain91 / 110098982
cervix0 / 481710 
connective tissue4 / 14925526
ear6 / 16212370
embryonic tissue11 / 21572250
esophagus0 / 202090 
eye8 / 21105437
heart2 / 8962622
intestine14 / 23447259
kidney21 / 21177799
larynx5 / 24145207
liver5 / 20774324
lung14 / 33697441
lymph0 / 442700 
lymph node1 / 9161010
mammary gland7 / 15327145
mouth2 / 6705229
muscle6 / 10771555
nerve0 / 157680 
ovary0 / 1020510 
pancreas9 / 21481241
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta19 / 28082567
prostate15 / 18934579
salivary gland0 / 201550 
skin8 / 21057437
spleen0 / 539520 
stomach3 / 9661931
testis8 / 33044224
thymus3 / 8113136
thyroid4 / 4747384
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus10 / 23287842
vascular4 / 5178077
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6912_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.33 ± 0.34
Basal Forebrain8.55 ± 0.34
Basal Part of Pons8.1 ± 0.44
Cerebellar Cortex8.13 ± 0.18
Cerebellar Nuclei8.65 ± 0.48
Claustrum8.46 ± 0.37
Epithalamus8.39 ± 0.47
Frontal Lobe8.27 ± 0.42
Globus Pallidus9.46 ± 0.24
Hypothalamus7.75 ± 0.34
Insula8.07 ± 0.42
Limbic Lobe8.42 ± 0.46
Mesencephalon8.31 ± 0.55
Myelencephalon8.4 ± 0.48
Occipital Lobe8.45 ± 0.31
Parietal Lobe8.32 ± 0.42
Pontine Tegmentum8.49 ± 0.33
Striatum8.55 ± 0.47
Subthalamus8.3 ± 0.15
Temporal Lobe8.29 ± 0.41
Thalamus8.41 ± 0.34
White Matter9.99 ± 0.25
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Arhgap21CBCerebellum100
100
Arhgap21CTXCerebral cortex100
100
Arhgap21HIPHippocampal region100
100
Arhgap21HPFHippocampal formation100
100
Arhgap21HYHypothalamus100
100
Arhgap21LSXLateral septal complex100
95.49
Arhgap21MBMidbrain100
100
Arhgap21MYMedulla98.18
100
Arhgap21OLFOlfactory bulb100
100
Arhgap21PPons99.48
100
Arhgap21PALPallidum100
100
Arhgap21RHPRetrohippocampal region100
100
Arhgap21sAMYStriatum-like amygdalar nuclei100
100
Arhgap21STRStriatum100
100
Arhgap21STRdStriatum dorsal region100
98.87
Arhgap21STRvStriatum ventral region100
100
Arhgap21THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00519478 18 1034 1051 TIQESSNLNEEDTGVTNR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018