AutismKB 2.0

Annotation Detail for ZNF687


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Basic Information Top
Gene Symbol:ZNF687 ( DKFZp781I1719,KIAA1441 )
Gene Full Name: zinc finger protein 687
Band: 1q21.3
Quick LinksEntrez ID:57592; OMIM: 610568; Uniprot ID:ZN687_HUMAN; ENSEMBL ID: ENSG00000143373; HGNC ID: 29277
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst3 / 6231948
fetus15 / 56401226
neonate2 / 3109764
infant0 / 236200 
juvenile0 / 555560 
adult49 / 193912125
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor5 / 9417853
cervical tumor2 / 3436658
chondrosarcoma3 / 8282336
colorectal tumor4 / 11424635
esophageal tumor1 / 1729057
gastrointestinal tumor0 / 1193690 
germ cell tumor13 / 26384549
glioma3 / 10688328
head and neck tumor3 / 13630222
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor2 / 9635920
lung tumor5 / 10312748
lymphoma1 / 7175513
non-neoplasia1 / 9725010
normal61 / 336030718
ovarian tumor2 / 7668226
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer4 / 10268038
retinoblastoma2 / 4635643
skin tumor2 / 12494916
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone1 / 7165513
bone marrow1 / 4880120
brain15 / 110098913
cervix2 / 4817141
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus1 / 2020949
eye13 / 21105461
heart0 / 896260 
intestine6 / 23447225
kidney1 / 2117774
larynx0 / 241450 
liver2 / 2077439
lung10 / 33697429
lymph0 / 442700 
lymph node4 / 9161043
mammary gland5 / 15327132
mouth2 / 6705229
muscle1 / 1077159
nerve0 / 157680 
ovary3 / 10205129
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta4 / 28082514
prostate4 / 18934521
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach0 / 966190 
testis10 / 33044230
thymus2 / 8113124
thyroid2 / 4747342
tonsil3 / 16999176
trachea0 / 524130 
umbilical cord2 / 13680146
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_2322_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.57 ± 0.58
Basal Forebrain4.58 ± 0.22
Basal Part of Pons4.31 ± 0.44
Cerebellar Cortex4.1 ± 0.61
Cerebellar Nuclei4.22 ± 0.63
Claustrum4.94 ± 0.86
Epithalamus3.95 ± 0.28
Frontal Lobe4.23 ± 0.53
Globus Pallidus4.88 ± 0.29
Hypothalamus3.91 ± 0.68
Insula4.19 ± 0.37
Limbic Lobe4.52 ± 0.68
Mesencephalon4.31 ± 0.72
Myelencephalon4.43 ± 0.65
Occipital Lobe4.58 ± 0.7
Parietal Lobe4.39 ± 0.62
Pontine Tegmentum4.32 ± 0.55
Striatum4.68 ± 0.51
Subthalamus4.36 ± 0.59
Temporal Lobe4.23 ± 0.68
Thalamus4.38 ± 0.55
White Matter4.34 ± 0.31
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Zfp687CBCerebellum81.35
100
Zfp687CTXCerebral cortex47.17
38.3
Zfp687HIPHippocampal region20.99
23.45
Zfp687HPFHippocampal formation22.65
23.24
Zfp687HYHypothalamus20.18
15.54
Zfp687LSXLateral septal complex35
24.97
Zfp687MBMidbrain28.27
24.5
Zfp687MYMedulla36.86
39.12
Zfp687OLFOlfactory bulb48.32
43.16
Zfp687PPons23.55
23.3
Zfp687PALPallidum24.19
20.7
Zfp687RHPRetrohippocampal region25.56
23.26
Zfp687sAMYStriatum-like amygdalar nuclei17.96
14.44
Zfp687STRStriatum23.87
17.84
Zfp687STRdStriatum dorsal region21.64
16.53
Zfp687STRvStriatum ventral region28.64
19.84
Zfp687THThalamus18.31
15.23
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00009321 37 1167 1203 ASALGLGDGEEEAPPSRSDPDGGDSPLPASGGPLTCK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018