AutismKB 2.0

Annotation Detail for USP36


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:USP36 ( DUB1 )
Gene Full Name: ubiquitin specific peptidase 36
Band: 17q25.3
Quick LinksEntrez ID:57602; OMIM: 612543; Uniprot ID:UBP36_HUMAN; ENSEMBL ID: ENSG00000055483; HGNC ID: 20062
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst3 / 6231948
fetus26 / 56401246
neonate3 / 3109796
infant0 / 236200 
juvenile4 / 5555671
adult266 / 1939121137
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor6 / 9417863
cervical tumor5 / 34366145
chondrosarcoma6 / 8282372
colorectal tumor18 / 114246157
esophageal tumor0 / 172900 
gastrointestinal tumor6 / 11936950
germ cell tumor28 / 263845106
glioma8 / 10688374
head and neck tumor13 / 13630295
kidney tumor4 / 6895958
leukemia5 / 9584252
liver tumor7 / 9635972
lung tumor18 / 103127174
lymphoma5 / 7175569
non-neoplasia4 / 9725041
normal267 / 336030779
ovarian tumor7 / 7668291
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer1 / 1026809
retinoblastoma1 / 4635621
skin tumor8 / 12494964
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites4 / 4001599
bladder1 / 2975733
blood5 / 12347840
bone6 / 7165583
bone marrow0 / 488010 
brain51 / 110098946
cervix5 / 48171103
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye12 / 21105456
heart4 / 8962644
intestine26 / 234472110
kidney13 / 21177761
larynx1 / 2414541
liver13 / 20774362
lung28 / 33697483
lymph5 / 44270112
lymph node3 / 9161032
mammary gland112 / 153271730
mouth9 / 67052134
muscle9 / 10771583
nerve0 / 157680 
ovary8 / 10205178
pancreas11 / 21481251
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta15 / 28082553
prostate4 / 18934521
salivary gland0 / 201550 
skin17 / 21057480
spleen4 / 5395274
stomach2 / 9661920
testis25 / 33044275
thymus6 / 8113173
thyroid3 / 4747363
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord4 / 13680292
uterus7 / 23287830
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220370_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts17.05
Adipocyte9.75
AdrenalCortex32.3
Adrenalgland9.25
Amygdala10.2
Appendix13.05
AtrioventricularNode13.15
BDCA4+_DentriticCells75.65
Bonemarrow11.9
BronchialEpithelialCells9.65
CD105+_Endothelial10.6
CD14+_Monocytes11.3
CD19+_BCells(neg._sel.)46.6
CD33+_Myeloid13.2
CD34+17
CD4+_Tcells38
CD56+_NKCells29.95
CD71+_EarlyErythroid10.1
CD8+_Tcells35.55
CardiacMyocytes23.15
Caudatenucleus9.15
Cerebellum8.55
CerebellumPeduncles12.4
CiliaryGanglion10.7
CingulateCortex10.7
Colorectaladenocarcinoma10.9
DorsalRootGanglion9.4
FetalThyroid10.6
Fetalbrain9.25
Fetalliver9.1
Fetallung7.75
GlobusPallidus8.5
Heart23.15
Hypothalamus10.8
Kidney9.6
Leukemia_chronicMyelogenousK-56211.8
Leukemia_promyelocytic-HL-609.3
Leukemialymphoblastic(MOLT-4)8.15
Liver16.6
Lung14.1
Lymphnode8.95
Lymphoma_burkitts(Daudi)13.4
Lymphoma_burkitts(Raji)17.55
MedullaOblongata9.05
OccipitalLobe9
OlfactoryBulb7.9
Ovary7.85
Pancreas10.1
PancreaticIslet11.3
ParietalLobe11.7
Pituitary11.85
Placenta10.75
Pons13.95
PrefrontalCortex10.7
Prostate11.8
Salivarygland8.65
SkeletalMuscle19.8
Skin10.1
SmoothMuscle11.15
Spinalcord11.25
SubthalamicNucleus9.75
SuperiorCervicalGanglion14.55
TemporalLobe9.8
Testis11.25
TestisGermCell8.85
TestisIntersitial8.95
TestisLeydigCell10.85
TestisSeminiferousTubule9.1
Thalamus10.9
Thymus8.25
Thyroid14.3
Tongue11.95
Tonsil10.5
Trachea8.3
TrigeminalGanglion19.7
Uterus8.35
UterusCorpus10.9
WholeBlood11.6
Wholebrain7.95
colon11.35
pineal_day13.34
pineal_night14
retina13.45
small_intestine10.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1262_PI416573500
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.57 ± 0.28
Basal Forebrain8.59 ± 0.32
Basal Part of Pons8.48 ± 0.24
Cerebellar Cortex8.53 ± 0.33
Cerebellar Nuclei8.27 ± 0.39
Claustrum8.79 ± 0.4
Epithalamus7.86 ± 0.23
Frontal Lobe8.3 ± 0.32
Globus Pallidus8.95 ± 0.25
Hypothalamus8.06 ± 0.13
Insula8.32 ± 0.37
Limbic Lobe8.57 ± 0.44
Mesencephalon8.45 ± 0.33
Myelencephalon8.45 ± 0.35
Occipital Lobe8.81 ± 0.36
Parietal Lobe8.51 ± 0.36
Pontine Tegmentum8.35 ± 0.38
Striatum8.77 ± 0.39
Subthalamus8.45 ± 0.19
Temporal Lobe8.4 ± 0.31
Thalamus8.41 ± 0.28
White Matter9.47 ± 0.24
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Usp36CBCerebellum66.37
96.18
Usp36CTXCerebral cortex82.7
69
Usp36HIPHippocampal region50.13
66.77
Usp36HPFHippocampal formation60.28
67.8
Usp36HYHypothalamus38.91
31.13
Usp36LSXLateral septal complex51.85
36.6
Usp36MBMidbrain44.3
41.11
Usp36MYMedulla53.51
57.23
Usp36OLFOlfactory bulb70.6
59.82
Usp36PPons48.89
49.89
Usp36PALPallidum39.48
34.99
Usp36RHPRetrohippocampal region77.79
69.98
Usp36sAMYStriatum-like amygdalar nuclei74.74
57.33
Usp36STRStriatum46.44
34.45
Usp36STRdStriatum dorsal region43.71
32.67
Usp36STRvStriatum ventral region43.96
31.73
Usp36THThalamus66.66
57.15
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00027706 21 632 652 SGAAHLCDSQETNCSTAGHSK Peptide Atlas
UBP36_HUMAN_2 14 2 15 PIVDKLKEALKPGR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved