AutismKB 2.0

Annotation Detail for DIP2B


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Basic Information Top
Gene Symbol:DIP2B ( KIAA1463,MGC104005 )
Gene Full Name: DIP2 disco-interacting protein 2 homolog B (Drosophila)
Band: 12q13.12
Quick LinksEntrez ID:57609; OMIM: 611379; Uniprot ID:DIP2B_HUMAN; ENSEMBL ID: ENSG00000066084; HGNC ID: 29284
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body7 / 7076198
blastocyst2 / 6231932
fetus38 / 56401267
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult91 / 193912146
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor6 / 11424652
esophageal tumor0 / 172900 
gastrointestinal tumor5 / 11936941
germ cell tumor4 / 26384515
glioma3 / 10688328
head and neck tumor7 / 13630251
kidney tumor2 / 6895929
leukemia2 / 9584220
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia4 / 9725041
normal171 / 336030750
ovarian tumor3 / 7668239
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer6 / 10268058
retinoblastoma1 / 4635621
skin tumor8 / 12494964
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder2 / 2975767
blood1 / 1234788
bone5 / 7165569
bone marrow1 / 4880120
brain31 / 110098928
cervix0 / 481710 
connective tissue5 / 14925533
ear3 / 16212185
embryonic tissue10 / 21572246
esophagus0 / 202090 
eye9 / 21105442
heart4 / 8962644
intestine11 / 23447246
kidney12 / 21177756
larynx1 / 2414541
liver4 / 20774319
lung8 / 33697423
lymph1 / 4427022
lymph node4 / 9161043
mammary gland9 / 15327158
mouth1 / 6705214
muscle2 / 10771518
nerve0 / 157680 
ovary3 / 10205129
pancreas18 / 21481283
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta26 / 28082592
prostate9 / 18934547
salivary gland0 / 201550 
skin23 / 210574109
spleen0 / 539520 
stomach3 / 9661931
testis7 / 33044221
thymus0 / 811310 
thyroid5 / 47473105
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus10 / 23287842
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P68162
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.67 ± 0.4
Basal Forebrain8.17 ± 0.49
Basal Part of Pons8.35 ± 0.35
Cerebellar Cortex8.4 ± 0.25
Cerebellar Nuclei8.83 ± 0.27
Claustrum8.03 ± 0.33
Epithalamus7.6 ± 0.51
Frontal Lobe7.96 ± 0.45
Globus Pallidus9.03 ± 0.48
Hypothalamus7.88 ± 0.31
Insula7.72 ± 0.27
Limbic Lobe7.92 ± 0.47
Mesencephalon8.26 ± 0.45
Myelencephalon8.14 ± 0.48
Occipital Lobe8.56 ± 0.59
Parietal Lobe8.05 ± 0.48
Pontine Tegmentum8.2 ± 0.42
Striatum8.14 ± 0.57
Subthalamus8.54 ± 0.43
Temporal Lobe7.88 ± 0.39
Thalamus8.53 ± 0.3
White Matter9.85 ± 0.3
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
AI317237CBCerebellum56.22
90.58
AI317237CTXCerebral cortex100
100
AI317237HIPHippocampal region55.18
89.72
AI317237HPFHippocampal formation64.18
81.66
AI317237HYHypothalamus70.16
60.54
AI317237LSXLateral septal complex71.61
58.08
AI317237MBMidbrain84.82
85.94
AI317237MYMedulla87.13
100
AI317237OLFOlfactory bulb87.05
85.75
AI317237PPons83.34
91.82
AI317237PALPallidum74.2
71.35
AI317237RHPRetrohippocampal region78.82
73.52
AI317237sAMYStriatum-like amygdalar nuclei43.69
33.18
AI317237STRStriatum69.32
55.35
AI317237STRdStriatum dorsal region70.11
57.62
AI317237STRvStriatum ventral region78.86
57.51
AI317237THThalamus94.71
92.62
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00026893 11 1171 1181 MSHSAVNALCR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018