AutismKB 2.0

Annotation Detail for TSHZ3


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Basic Information Top
Gene Symbol:TSHZ3 ( FLJ54422,KIAA1474,TSH3,ZNF537 )
Gene Full Name: teashirt zinc finger homeobox 3
Band: 19q12
Quick LinksEntrez ID:57616; OMIM: NA; Uniprot ID:TSH3_HUMAN; ENSEMBL ID: ENSG00000121297; HGNC ID: 30700
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus40 / 56401270
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult37 / 193912119
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor3 / 26384511
glioma4 / 10688337
head and neck tumor0 / 1363020 
kidney tumor2 / 6895929
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal87 / 336030725
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone0 / 716550 
bone marrow0 / 488010 
brain33 / 110098929
cervix0 / 481710 
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye3 / 21105414
heart0 / 896260 
intestine0 / 2344720 
kidney3 / 21177714
larynx0 / 241450 
liver0 / 2077430 
lung9 / 33697426
lymph0 / 442700 
lymph node0 / 916100 
mammary gland5 / 15327132
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary0 / 1020510 
pancreas7 / 21481232
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate4 / 18934521
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach1 / 9661910
testis5 / 33044215
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus15 / 23287864
vascular10 / 51780193
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P361014
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.3 ± 0.56
Basal Forebrain7.26 ± 0.3
Basal Part of Pons7.88 ± 0.63
Cerebellar Cortex6.88 ± 0.3
Cerebellar Nuclei7.06 ± 0.44
Claustrum7.11 ± 0.64
Epithalamus7.13 ± 0.61
Frontal Lobe7.3 ± 0.68
Globus Pallidus6.22 ± 0.81
Hypothalamus7.38 ± 0.49
Insula7.73 ± 0.3
Limbic Lobe7.39 ± 0.79
Mesencephalon7.05 ± 0.6
Myelencephalon7.52 ± 0.67
Occipital Lobe8.15 ± 0.38
Parietal Lobe7.68 ± 0.53
Pontine Tegmentum7.39 ± 0.6
Striatum6.58 ± 1.06
Subthalamus7.42 ± 0.46
Temporal Lobe7.86 ± 0.36
Thalamus7.59 ± 0.69
White Matter5.85 ± 0.74
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tshz3CBCerebellum0.97
1.48
Tshz3CTXCerebral cortex26.02
18.87
Tshz3HIPHippocampal region2.8
2.83
Tshz3HPFHippocampal formation10.13
9.15
Tshz3HYHypothalamus0.42
0.39
Tshz3LSXLateral septal complex0.55
0.6
Tshz3MBMidbrain2.29
2.6
Tshz3MYMedulla4.8
4.58
Tshz3OLFOlfactory bulb8.31
7.72
Tshz3PPons2
2.03
Tshz3PALPallidum3.73
3.45
Tshz3RHPRetrohippocampal region21.08
16.88
Tshz3sAMYStriatum-like amygdalar nuclei0.73
0.65
Tshz3STRStriatum2.97
2.83
Tshz3STRdStriatum dorsal region3.41
3.4
Tshz3STRvStriatum ventral region3.74
3.05
Tshz3THThalamus1.26
1.41
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018