AutismKB 2.0

Annotation Detail for ZBTB2


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Basic Information Top
Gene Symbol:ZBTB2 ( ZNF437 )
Gene Full Name: zinc finger and BTB domain containing 2
Band: 6q25.1
Quick LinksEntrez ID:57621; OMIM: NA; Uniprot ID:ZBTB2_HUMAN; ENSEMBL ID: ENSG00000181472; HGNC ID: 20868
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst2 / 6231932
fetus1 / 5640121
neonate1 / 3109732
infant0 / 236200 
juvenile1 / 5555617
adult34 / 193912117
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor1 / 3436629
chondrosarcoma2 / 8282324
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor6 / 26384522
glioma4 / 10688337
head and neck tumor5 / 13630236
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal41 / 336030712
ovarian tumor0 / 766820 
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer5 / 10268048
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood0 / 1234780 
bone2 / 7165527
bone marrow5 / 48801102
brain11 / 11009899
cervix1 / 4817120
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye2 / 2110549
heart0 / 896260 
intestine2 / 2344728
kidney4 / 21177718
larynx0 / 241450 
liver1 / 2077434
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas10 / 21481246
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta8 / 28082528
prostate5 / 18934526
salivary gland0 / 201550 
skin1 / 2105744
spleen2 / 5395237
stomach0 / 966190 
testis4 / 33044212
thymus2 / 8113124
thyroid6 / 47473126
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord1 / 1368073
uterus6 / 23287825
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P82108
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.77 ± 0.28
Basal Forebrain6.62 ± 0.24
Basal Part of Pons6.24 ± 0.39
Cerebellar Cortex6.47 ± 0.28
Cerebellar Nuclei6.51 ± 0.34
Claustrum6.69 ± 0.52
Epithalamus6.58 ± 0.24
Frontal Lobe6.46 ± 0.33
Globus Pallidus6.55 ± 0.33
Hypothalamus6.47 ± 0.14
Insula6.56 ± 0.35
Limbic Lobe6.98 ± 0.4
Mesencephalon6.58 ± 0.37
Myelencephalon6.62 ± 0.32
Occipital Lobe7.18 ± 0.39
Parietal Lobe6.65 ± 0.28
Pontine Tegmentum6.72 ± 0.37
Striatum7.07 ± 0.32
Subthalamus6.34 ± 0.51
Temporal Lobe6.59 ± 0.29
Thalamus6.46 ± 0.28
White Matter7.46 ± 0.3
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00040814 17 466 482 HSCQNQNSDVFALDEGR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018