AutismKB 2.0

Annotation Detail for EP400


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Basic Information Top
Gene Symbol:EP400 ( CAGH32,DKFZP434I225,FLJ42018,FLJ45115,P400,TNRC12 )
Gene Full Name: E1A binding protein p400
Band: 12q24.33
Quick LinksEntrez ID:57634; OMIM: 606265; Uniprot ID:EP400_HUMAN; ENSEMBL ID: ENSG00000183495; HGNC ID: 11958
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst6 / 6231996
fetus55 / 56401297
neonate1 / 3109732
infant0 / 236200 
juvenile2 / 5555635
adult128 / 193912166
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor6 / 9417863
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor18 / 114246157
esophageal tumor0 / 172900 
gastrointestinal tumor9 / 11936975
germ cell tumor30 / 263845113
glioma11 / 106883102
head and neck tumor11 / 13630280
kidney tumor5 / 6895972
leukemia8 / 9584283
liver tumor9 / 9635993
lung tumor9 / 10312787
lymphoma8 / 71755111
non-neoplasia9 / 9725092
normal221 / 336030765
ovarian tumor6 / 7668278
pancreatic tumor9 / 10461686
primitive neuroectodermal tumor of the CNS9 / 12568071
prostate cancer4 / 10268038
retinoblastoma2 / 4635643
skin tumor5 / 12494940
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland0 / 331970 
ascites6 / 40015149
bladder2 / 2975767
blood5 / 12347840
bone1 / 7165513
bone marrow4 / 4880181
brain64 / 110098958
cervix1 / 4817120
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue15 / 21572269
esophagus0 / 202090 
eye15 / 21105471
heart11 / 89626122
intestine26 / 234472110
kidney14 / 21177766
larynx2 / 2414582
liver14 / 20774367
lung21 / 33697462
lymph3 / 4427067
lymph node16 / 91610174
mammary gland10 / 15327165
mouth9 / 67052134
muscle0 / 1077150 
nerve0 / 157680 
ovary6 / 10205158
pancreas22 / 214812102
parathyroid4 / 20539194
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta12 / 28082542
prostate8 / 18934542
salivary gland0 / 201550 
skin5 / 21057423
spleen6 / 53952111
stomach6 / 9661962
testis32 / 33044296
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus8 / 23287834
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212376_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts38.55
Adipocyte24.35
AdrenalCortex25.7
Adrenalgland25.7
Amygdala28.6
Appendix23.55
AtrioventricularNode16.1
BDCA4+_DentriticCells27.8
Bonemarrow24.4
BronchialEpithelialCells21.85
CD105+_Endothelial25.55
CD14+_Monocytes23.15
CD19+_BCells(neg._sel.)26.85
CD33+_Myeloid29.25
CD34+40.1
CD4+_Tcells28.4
CD56+_NKCells26.6
CD71+_EarlyErythroid19.3
CD8+_Tcells30.25
CardiacMyocytes36.45
Caudatenucleus22.25
Cerebellum21.8
CerebellumPeduncles27.2
CiliaryGanglion17.25
CingulateCortex24.9
Colorectaladenocarcinoma32.6
DorsalRootGanglion18.75
FetalThyroid23.8
Fetalbrain28
Fetalliver23.8
Fetallung22.95
GlobusPallidus17.15
Heart32.7
Hypothalamus27.3
Kidney21.6
Leukemia_chronicMyelogenousK-56233.45
Leukemia_promyelocytic-HL-6021.95
Leukemialymphoblastic(MOLT-4)26.9
Liver32.4
Lung29.5
Lymphnode25.45
Lymphoma_burkitts(Daudi)32.1
Lymphoma_burkitts(Raji)39
MedullaOblongata27.9
OccipitalLobe22.4
OlfactoryBulb19.7
Ovary14.4
Pancreas19.2
PancreaticIslet25
ParietalLobe26.05
Pituitary28.65
Placenta26.5
Pons22.8
PrefrontalCortex31.25
Prostate28.3
Salivarygland19.4
SkeletalMuscle40.4
Skin17.15
SmoothMuscle28.4
Spinalcord27.1
SubthalamicNucleus23
SuperiorCervicalGanglion28.25
TemporalLobe18.85
Testis30
TestisGermCell28
TestisIntersitial23.85
TestisLeydigCell24.6
TestisSeminiferousTubule22.05
Thalamus30.8
Thymus26.3
Thyroid30.25
Tongue23.85
Tonsil30.85
Trachea20.8
TrigeminalGanglion24.15
Uterus20.55
UterusCorpus26.2
WholeBlood26.85
Wholebrain21.45
colon25.05
pineal_day33.84
pineal_night34.08
retina32.675
small_intestine31.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P253158
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.82 ± 0.51
Basal Forebrain4.81 ± 0.44
Basal Part of Pons4.88 ± 0.32
Cerebellar Cortex5.11 ± 0.22
Cerebellar Nuclei4.65 ± 0.53
Claustrum4.8 ± 0.41
Epithalamus4.91 ± 0.34
Frontal Lobe4.81 ± 0.41
Globus Pallidus4.36 ± 0.4
Hypothalamus4.87 ± 0.22
Insula4.93 ± 0.31
Limbic Lobe4.94 ± 0.46
Mesencephalon4.86 ± 0.48
Myelencephalon4.82 ± 0.45
Occipital Lobe5.1 ± 0.36
Parietal Lobe4.96 ± 0.42
Pontine Tegmentum4.91 ± 0.44
Striatum4.84 ± 0.42
Subthalamus4.61 ± 0.39
Temporal Lobe4.96 ± 0.41
Thalamus4.76 ± 0.39
White Matter4.78 ± 0.25
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ep400CBCerebellum38.41
45.96
Ep400CTXCerebral cortex100
86.52
Ep400HIPHippocampal region69.65
100
Ep400HPFHippocampal formation75.36
90.54
Ep400HYHypothalamus72.77
57.64
Ep400LSXLateral septal complex83.8
61.78
Ep400MBMidbrain72.73
66.29
Ep400MYMedulla76.31
83.14
Ep400OLFOlfactory bulb80.56
70.33
Ep400PPons70.05
74.46
Ep400PALPallidum70.47
62.82
Ep400RHPRetrohippocampal region85.79
72.23
Ep400sAMYStriatum-like amygdalar nuclei82.38
59.94
Ep400STRStriatum75.21
56.23
Ep400STRdStriatum dorsal region74.68
57.76
Ep400STRvStriatum ventral region72.74
49.78
Ep400THThalamus77.06
66.15
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
EP400_HUMAN_281 10 281 290 QVLQGPPLPR PRIDE
PAp00063985 19 2562 2580 AQPAITTGGSAAVLAGTIK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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