AutismKB 2.0

Annotation Detail for ARHGAP23


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Basic Information Top
Gene Symbol:ARHGAP23 ( KIAA1501 )
Gene Full Name: Rho GTPase activating protein 23
Band: 17q12
Quick LinksEntrez ID:57636; OMIM: 610590; Uniprot ID:RHG23_HUMAN; ENSEMBL ID: ENSG00000225485; HGNC ID: 29293
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst3 / 6231948
fetus17 / 56401230
neonate0 / 310970 
infant1 / 2362042
juvenile2 / 5555635
adult106 / 193912154
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor7 / 9417874
cervical tumor4 / 34366116
chondrosarcoma6 / 8282372
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor4 / 26384515
glioma8 / 10688374
head and neck tumor35 / 136302256
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor2 / 9635920
lung tumor5 / 10312748
lymphoma0 / 717550 
non-neoplasia8 / 9725082
normal108 / 336030732
ovarian tumor9 / 76682117
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites1 / 4001524
bladder3 / 29757100
blood0 / 1234780 
bone3 / 7165541
bone marrow0 / 488010 
brain35 / 110098931
cervix4 / 4817183
connective tissue6 / 14925540
ear1 / 1621261
embryonic tissue11 / 21572250
esophagus0 / 202090 
eye6 / 21105428
heart5 / 8962655
intestine5 / 23447221
kidney2 / 2117779
larynx2 / 2414582
liver2 / 2077439
lung16 / 33697447
lymph0 / 442700 
lymph node2 / 9161021
mammary gland8 / 15327152
mouth22 / 67052328
muscle0 / 1077150 
nerve2 / 15768126
ovary11 / 102051107
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta9 / 28082532
prostate5 / 18934526
salivary gland8 / 20155396
skin0 / 2105740 
spleen1 / 5395218
stomach1 / 9661910
testis1 / 3304423
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_4013_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.53 ± 0.54
Basal Forebrain8.14 ± 0.48
Basal Part of Pons7.48 ± 0.38
Cerebellar Cortex7.31 ± 0.24
Cerebellar Nuclei8.17 ± 0.51
Claustrum8.18 ± 0.4
Epithalamus6.71 ± 0.91
Frontal Lobe7.44 ± 0.67
Globus Pallidus9.16 ± 0.32
Hypothalamus7.32 ± 0.55
Insula7.38 ± 0.41
Limbic Lobe7.44 ± 0.76
Mesencephalon7.85 ± 0.48
Myelencephalon7.62 ± 0.67
Occipital Lobe7.56 ± 0.53
Parietal Lobe7.47 ± 0.62
Pontine Tegmentum7.66 ± 0.56
Striatum7.74 ± 0.7
Subthalamus7.94 ± 0.24
Temporal Lobe7.4 ± 0.58
Thalamus7.83 ± 0.38
White Matter9.9 ± 0.7
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018