AutismKB 2.0

Annotation Detail for ZBTB4


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Basic Information Top
Gene Symbol:ZBTB4 ( KAISO-L1,KIAA1538,ZNF903 )
Gene Full Name: zinc finger and BTB domain containing 4
Band: 17p13.1
Quick LinksEntrez ID:57659; OMIM: 612308; Uniprot ID:ZBTB4_HUMAN; ENSEMBL ID: ENSG00000174282; HGNC ID: 23847
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst2 / 6231932
fetus40 / 56401270
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult114 / 193912158
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor4 / 34366116
chondrosarcoma5 / 8282360
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor6 / 26384522
glioma21 / 106883196
head and neck tumor11 / 13630280
kidney tumor3 / 6895943
leukemia3 / 9584231
liver tumor3 / 9635931
lung tumor6 / 10312758
lymphoma2 / 7175527
non-neoplasia5 / 9725051
normal194 / 336030757
ovarian tumor0 / 766820 
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer5 / 10268048
retinoblastoma2 / 4635643
skin tumor2 / 12494916
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland2 / 3319760
ascites0 / 400150 
bladder0 / 297570 
blood4 / 12347832
bone5 / 7165569
bone marrow0 / 488010 
brain78 / 110098970
cervix4 / 4817183
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue9 / 21572241
esophagus0 / 202090 
eye22 / 211054104
heart6 / 8962666
intestine3 / 23447212
kidney10 / 21177747
larynx0 / 241450 
liver5 / 20774324
lung32 / 33697494
lymph0 / 442700 
lymph node4 / 9161043
mammary gland8 / 15327152
mouth5 / 6705274
muscle1 / 1077159
nerve1 / 1576863
ovary2 / 10205119
pancreas16 / 21481274
parathyroid7 / 20539340
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta6 / 28082521
prostate10 / 18934552
salivary gland3 / 20155148
skin9 / 21057442
spleen0 / 539520 
stomach1 / 9661910
testis11 / 33044233
thymus6 / 8113173
thyroid4 / 4747384
tonsil0 / 169990 
trachea5 / 5241395
umbilical cord0 / 136800 
uterus20 / 23287885
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P100654
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.55 ± 0.33
Basal Forebrain9.84 ± 0.09
Basal Part of Pons10.13 ± 0.18
Cerebellar Cortex9.93 ± 0.21
Cerebellar Nuclei10.13 ± 0.19
Claustrum9.81 ± 0.33
Epithalamus9.78 ± 0.26
Frontal Lobe9.89 ± 0.25
Globus Pallidus9.79 ± 0.3
Hypothalamus9.85 ± 0.23
Insula10.03 ± 0.26
Limbic Lobe9.64 ± 0.34
Mesencephalon9.86 ± 0.26
Myelencephalon9.79 ± 0.32
Occipital Lobe9.65 ± 0.35
Parietal Lobe9.98 ± 0.27
Pontine Tegmentum9.77 ± 0.26
Striatum9.39 ± 0.31
Subthalamus10.2 ± 0.21
Temporal Lobe9.87 ± 0.27
Thalamus9.86 ± 0.3
White Matter9.6 ± 0.16
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Zbtb4CBCerebellum49.66
70.14
Zbtb4CTXCerebral cortex81.06
62.78
Zbtb4HIPHippocampal region47.69
61.01
Zbtb4HPFHippocampal formation61.39
63.26
Zbtb4HYHypothalamus37.01
30.6
Zbtb4LSXLateral septal complex20.91
15.62
Zbtb4MBMidbrain47.92
44.73
Zbtb4MYMedulla53.21
59.37
Zbtb4OLFOlfactory bulb64.31
59.18
Zbtb4PPons44.65
47.99
Zbtb4PALPallidum19.2
17.62
Zbtb4RHPRetrohippocampal region82.64
65.68
Zbtb4sAMYStriatum-like amygdalar nuclei23.68
16.84
Zbtb4STRStriatum19.79
15.38
Zbtb4STRdStriatum dorsal region21.89
17.34
Zbtb4STRvStriatum ventral region10.8
8.62
Zbtb4THThalamus64.21
59.66
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018