AutismKB 2.0

Annotation Detail for GPAM


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Basic Information Top
Gene Symbol:GPAM ( GPAT,GPAT1,KIAA1560,MGC26846 )
Gene Full Name: glycerol-3-phosphate acyltransferase, mitochondrial
Band: 10q25.2
Quick LinksEntrez ID:57678; OMIM: 602395; Uniprot ID:GPAT1_HUMAN; ENSEMBL ID: ENSG00000119927; HGNC ID: 24865
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus57 / 564012101
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult66 / 193912134
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor2 / 2638457
glioma1 / 1068839
head and neck tumor4 / 13630229
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor12 / 96359124
lung tumor0 / 1031270 
lymphoma4 / 7175555
non-neoplasia5 / 9725051
normal189 / 336030756
ovarian tumor4 / 7668252
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma1 / 4635621
skin tumor2 / 12494916
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue19 / 131061449
adrenal gland4 / 33197120
ascites1 / 4001524
bladder0 / 297570 
blood1 / 1234788
bone2 / 7165527
bone marrow2 / 4880140
brain39 / 110098935
cervix0 / 481710 
connective tissue0 / 1492550 
ear1 / 1621261
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye3 / 21105414
heart4 / 8962644
intestine1 / 2344724
kidney3 / 21177714
larynx0 / 241450 
liver24 / 207743115
lung3 / 3369748
lymph4 / 4427090
lymph node11 / 91610120
mammary gland5 / 15327132
mouth2 / 6705229
muscle3 / 10771527
nerve2 / 15768126
ovary5 / 10205148
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta2 / 2808257
prostate0 / 1893450 
salivary gland0 / 201550 
skin7 / 21057433
spleen0 / 539520 
stomach1 / 9661910
testis11 / 33044233
thymus1 / 8113112
thyroid2 / 4747342
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus15 / 23287864
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P104237
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.13 ± 0.65
Basal Forebrain5.12 ± 0.15
Basal Part of Pons3.57 ± 0.66
Cerebellar Cortex3.76 ± 0.62
Cerebellar Nuclei4.17 ± 0.77
Claustrum4.58 ± 0.62
Epithalamus4.05 ± 0.97
Frontal Lobe4.26 ± 0.73
Globus Pallidus6.21 ± 0.51
Hypothalamus4.35 ± 0.7
Insula4.45 ± 0.53
Limbic Lobe4.23 ± 0.72
Mesencephalon4.86 ± 0.55
Myelencephalon4.56 ± 0.82
Occipital Lobe4.78 ± 0.72
Parietal Lobe4.65 ± 0.73
Pontine Tegmentum4.76 ± 0.69
Striatum5.46 ± 0.45
Subthalamus4.42 ± 0.72
Temporal Lobe4.35 ± 0.73
Thalamus5 ± 0.48
White Matter4.38 ± 0.41
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
GpamCBCerebellum9.92
11.77
GpamCTXCerebral cortex8.53
6.94
GpamHIPHippocampal region5.03
4.47
GpamHPFHippocampal formation5.32
4.38
GpamHYHypothalamus0.44
0.68
GpamLSXLateral septal complex0.87
0.79
GpamMBMidbrain2.96
4.09
GpamMYMedulla3.43
4.5
GpamOLFOlfactory bulb7.17
5.04
GpamPPons2.37
3.44
GpamPALPallidum0.57
0.39
GpamRHPRetrohippocampal region6.11
4.48
GpamsAMYStriatum-like amygdalar nuclei0.76
0.71
GpamSTRStriatum1.58
1.15
GpamSTRdStriatum dorsal region1.86
1.34
GpamSTRvStriatum ventral region1.09
0.7
GpamTHThalamus1.45
1.18
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018