Annotation Detail for ALS2
Basic Information Top
| Gene Symbol: | ALS2 ( ALS2CR6,ALSJ,FLJ31851,IAHSP,KIAA1563,MGC87187,PLSJ ) |
|---|---|
| Gene Full Name: | amyotrophic lateral sclerosis 2 (juvenile) |
| Band: | 2q33.1 |
| Quick Links | Entrez ID:57679; OMIM: 606352; Uniprot ID:ALS2_HUMAN; ENSEMBL ID: ENSG00000003393; HGNC ID: 443 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.471096
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 2 / 70761 | 28 |  |
| blastocyst | 4 / 62319 | 64 |  |
| fetus | 33 / 564012 | 58 | |
| neonate | 1 / 31097 | 32 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 56 / 1939121 | 28 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 1 / 12794 | 78 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 2 / 94178 | 21 | |
| cervical tumor | 1 / 34366 | 29 | |
| chondrosarcoma | 3 / 82823 | 36 | |
| colorectal tumor | 3 / 114246 | 26 | |
| esophageal tumor | 2 / 17290 | 115 | |
| gastrointestinal tumor | 1 / 119369 | 8 |  |
| germ cell tumor | 12 / 263845 | 45 | |
| glioma | 1 / 106883 | 9 | |
| head and neck tumor | 3 / 136302 | 22 | |
| kidney tumor | 2 / 68959 | 29 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 1 / 96359 | 10 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 1 / 97250 | 10 | |
| normal | 139 / 3360307 | 41 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 4 / 104616 | 38 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 3 / 124949 | 24 | |
| soft tissue/muscle tissue tumor | 6 / 125191 | 47 | |
| uterine tumor | 3 / 90257 | 33 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 1 / 33197 | 30 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 1 / 123478 | 8 | |
| bone | 2 / 71655 | 27 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 51 / 1100989 | 46 | |
| cervix | 1 / 48171 | 20 | |
| connective tissue | 3 / 149255 | 20 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 7 / 215722 | 32 | |
| esophagus | 2 / 20209 | 98 | |
| eye | 3 / 211054 | 14 | |
| heart | 3 / 89626 | 33 | |
| intestine | 4 / 234472 | 17 | |
| kidney | 8 / 211777 | 37 | |
| larynx | 0 / 24145 | 0 | |
| liver | 1 / 207743 | 4 | |
| lung | 9 / 336974 | 26 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 7 / 91610 | 76 | |
| mammary gland | 8 / 153271 | 52 | |
| mouth | 3 / 67052 | 44 | |
| muscle | 6 / 107715 | 55 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 4 / 214812 | 18 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 1 / 41328 | 24 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 4 / 280825 | 14 | |
| prostate | 3 / 189345 | 15 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 17 / 210574 | 80 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 3 / 96619 | 31 | |
| testis | 13 / 330442 | 39 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 2 / 52413 | 38 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 9 / 232878 | 38 | |
| vascular | 1 / 51780 | 19 | |
Microarray in - Probe name: A_24_P222410
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 4.42 ± 0.78 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 3.91 ± 0.36 | |
| Basal Part of Pons | 4.19 ± 0.61 | |
| Cerebellar Cortex | 5.04 ± 0.36 | |
| Cerebellar Nuclei | 4.15 ± 0.34 | |
| Claustrum | 4.28 ± 0.86 | |
| Epithalamus | 4.71 ± 0.33 | |
| Frontal Lobe | 4.29 ± 0.51 | |
| Globus Pallidus | 3.59 ± 0.24 | |
| Hypothalamus | 3.82 ± 0.59 | |
| Insula | 4.1 ± 0.59 | |
| Limbic Lobe | 4.41 ± 0.58 | |
| Mesencephalon | 4.31 ± 0.79 | |
| Myelencephalon | 4.24 ± 0.6 | |
| Occipital Lobe | 4.53 ± 0.53 | |
| Parietal Lobe | 4.38 ± 0.64 | |
| Pontine Tegmentum | 4.29 ± 0.6 | |
| Striatum | 3.61 ± 0.58 | |
| Subthalamus | 4.56 ± 0.25 | |
| Temporal Lobe | 4.4 ± 0.6 | |
| Thalamus | 4.15 ± 0.58 | |
| White Matter | 4.01 ± 0.75 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Als2 | CB | Cerebellum | 0 | |
| 0 | | |||
| Als2 | CTX | Cerebral cortex | 0 | |
| 0 | | |||
| Als2 | HIP | Hippocampal region | 0 | |
| 0 | | |||
| Als2 | HPF | Hippocampal formation | 0 | |
| 0 | | |||
| Als2 | HY | Hypothalamus | 0 | |
| 0 | | |||
| Als2 | LSX | Lateral septal complex | 0 | |
| 0 | | |||
| Als2 | MB | Midbrain | 0 | |
| 0 | | |||
| Als2 | MY | Medulla | 0 | |
| 0 | | |||
| Als2 | OLF | Olfactory bulb | 0 | |
| 0 | | |||
| Als2 | P | Pons | 0 | |
| 0 | | |||
| Als2 | PAL | Pallidum | 0 | |
| 0 | | |||
| Als2 | RHP | Retrohippocampal region | 0 | |
| 0 | | |||
| Als2 | sAMY | Striatum-like amygdalar nuclei | 0 | |
| 0 | | |||
| Als2 | STR | Striatum | 0 | |
| 0 | | |||
| Als2 | STRd | Striatum dorsal region | 0 | |
| 0 | | |||
| Als2 | STRv | Striatum ventral region | 0 | |
| 0 | | |||
| Als2 | TH | Thalamus | 0 | |
| 0 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| ALS2_HUMAN_1276 | 5 | 1276 | 1280 | PKVFR | PRIDE |