AutismKB 2.0

Annotation Detail for PRX


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Basic Information Top
Gene Symbol:PRX ( CMT4F,KIAA1620 )
Gene Full Name: periaxin
Band: 19q13.2
Quick LinksEntrez ID:57716; OMIM: 605725; Uniprot ID:PRAX_HUMAN; ENSEMBL ID: ENSG00000105227; HGNC ID: 13797
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst2 / 6231932
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile7 / 55556125
adult14 / 19391217
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor3 / 26384511
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal34 / 336030710
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain9 / 11009898
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye5 / 21105423
heart0 / 896260 
intestine3 / 23447212
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle1 / 1077159
nerve9 / 15768570
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate1 / 1893455
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220024_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts20.6
Adipocyte23.95
AdrenalCortex50.6
Adrenalgland18.3
Amygdala13.55
Appendix16.35
AtrioventricularNode113.95
BDCA4+_DentriticCells17.45
Bonemarrow21.55
BronchialEpithelialCells12.25
CD105+_Endothelial20.8
CD14+_Monocytes18.05
CD19+_BCells(neg._sel.)17
CD33+_Myeloid21.1
CD34+21.25
CD4+_Tcells23.65
CD56+_NKCells20.55
CD71+_EarlyErythroid24.9
CD8+_Tcells14.25
CardiacMyocytes20.65
Caudatenucleus20.55
Cerebellum16.4
CerebellumPeduncles34.75
CiliaryGanglion68.35
CingulateCortex27.75
Colorectaladenocarcinoma16.5
DorsalRootGanglion188.75
FetalThyroid26.55
Fetalbrain18.25
Fetalliver17.95
Fetallung15.5
GlobusPallidus18.15
Heart31.9
Hypothalamus18.9
Kidney22.7
Leukemia_chronicMyelogenousK-56221.45
Leukemia_promyelocytic-HL-6017.55
Leukemialymphoblastic(MOLT-4)16.3
Liver22.6
Lung52.05
Lymphnode14.8
Lymphoma_burkitts(Daudi)25.15
Lymphoma_burkitts(Raji)25.7
MedullaOblongata18.6
OccipitalLobe16.5
OlfactoryBulb235.35
Ovary13.45
Pancreas12.3
PancreaticIslet18.75
ParietalLobe28.8
Pituitary30.8
Placenta19.6
Pons34.35
PrefrontalCortex23
Prostate16.7
Salivarygland21.05
SkeletalMuscle33.9
Skin35.2
SmoothMuscle20.15
Spinalcord43.85
SubthalamicNucleus38.95
SuperiorCervicalGanglion73
TemporalLobe28.35
Testis17.55
TestisGermCell14.85
TestisIntersitial18.3
TestisLeydigCell20.4
TestisSeminiferousTubule32.15
Thalamus21.05
Thymus9.5
Thyroid21.9
Tongue28.65
Tonsil22.05
Trachea17.05
TrigeminalGanglion102.95
Uterus14.3
UterusCorpus17.2
WholeBlood9.25
Wholebrain13.1
colon16.55
pineal_day25.64
pineal_night23.5
retina33.875
small_intestine16.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P390909
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.27 ± 0.91
Basal Forebrain1.89 ± 0.26
Basal Part of Pons1.54 ± 0.29
Cerebellar Cortex1.68 ± 0.71
Cerebellar Nuclei2.16 ± 0.7
Claustrum2.76 ± 0.88
Epithalamus1.62 ± 1
Frontal Lobe1.76 ± 0.7
Globus Pallidus2.46 ± 0.4
Hypothalamus1.85 ± 0.68
Insula1.85 ± 0.75
Limbic Lobe1.88 ± 0.66
Mesencephalon2.07 ± 0.69
Myelencephalon1.93 ± 0.71
Occipital Lobe1.88 ± 0.62
Parietal Lobe1.88 ± 0.69
Pontine Tegmentum1.92 ± 0.64
Striatum2.11 ± 0.6
Subthalamus1.99 ± 0.65
Temporal Lobe1.79 ± 0.6
Thalamus1.87 ± 0.59
White Matter2.42 ± 0.45
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PRAX_HUMAN_216 13 216 228 KAKVEAEVAAGAR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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