AutismKB 2.0

Annotation Detail for KIAA1632


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Basic Information Top
Gene Symbol:KIAA1632 ( DKFZp667P2311,HEEW1 )
Gene Full Name: KIAA1632
Band: 18q12.3
Quick LinksEntrez ID:57724; OMIM: NA; Uniprot ID:K1632_HUMAN; ENSEMBL ID: ENSG00000152223; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst2 / 6231932
fetus13 / 56401223
neonate1 / 3109732
infant0 / 236200 
juvenile2 / 5555635
adult76 / 193912139
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor2 / 3436658
chondrosarcoma1 / 8282312
colorectal tumor19 / 114246166
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor8 / 26384530
glioma0 / 1068830 
head and neck tumor4 / 13630229
kidney tumor1 / 6895914
leukemia3 / 9584231
liver tumor4 / 9635941
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal83 / 336030724
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood4 / 12347832
bone2 / 7165527
bone marrow0 / 488010 
brain17 / 110098915
cervix2 / 4817141
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye3 / 21105414
heart1 / 8962611
intestine20 / 23447285
kidney7 / 21177733
larynx3 / 24145124
liver9 / 20774343
lung3 / 3369748
lymph0 / 442700 
lymph node9 / 9161098
mammary gland6 / 15327139
mouth0 / 670520 
muscle5 / 10771546
nerve2 / 15768126
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta7 / 28082524
prostate2 / 18934510
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach1 / 9661910
testis8 / 33044224
thymus6 / 8113173
thyroid1 / 4747321
tonsil0 / 169990 
trachea5 / 5241395
umbilical cord0 / 136800 
uterus5 / 23287821
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P392146
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.1 ± 0.34
Basal Forebrain5.05 ± 0.26
Basal Part of Pons4.96 ± 0.27
Cerebellar Cortex5.25 ± 0.31
Cerebellar Nuclei5.16 ± 0.38
Claustrum4.96 ± 0.66
Epithalamus5.16 ± 0.23
Frontal Lobe5.09 ± 0.35
Globus Pallidus5.13 ± 0.15
Hypothalamus5.2 ± 0.35
Insula5.11 ± 0.2
Limbic Lobe5.21 ± 0.41
Mesencephalon5.33 ± 0.44
Myelencephalon5.16 ± 0.39
Occipital Lobe5.37 ± 0.29
Parietal Lobe5.18 ± 0.44
Pontine Tegmentum5.13 ± 0.36
Striatum5.16 ± 0.32
Subthalamus5.01 ± 0.46
Temporal Lobe5.14 ± 0.31
Thalamus5.15 ± 0.33
White Matter5.65 ± 0.19
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
5430411K18RikCBCerebellum14.01
15.84
5430411K18RikCTXCerebral cortex12.12
8.47
5430411K18RikHIPHippocampal region10.7
9.99
5430411K18RikHPFHippocampal formation11.66
9.96
5430411K18RikHYHypothalamus1.34
0.96
5430411K18RikLSXLateral septal complex0.32
0.19
5430411K18RikMBMidbrain11.14
9.47
5430411K18RikMYMedulla10.24
10.23
5430411K18RikOLFOlfactory bulb16.24
12.56
5430411K18RikPPons14.16
14.29
5430411K18RikPALPallidum0.85
0.65
5430411K18RikRHPRetrohippocampal region13.16
9.91
5430411K18RiksAMYStriatum-like amygdalar nuclei0.99
0.79
5430411K18RikSTRStriatum2.44
2.27
5430411K18RikSTRdStriatum dorsal region2.87
2.93
5430411K18RikSTRvStriatum ventral region2.31
1.5
5430411K18RikTHThalamus4.38
4.01
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018