AutismKB 2.0

Annotation Detail for WDR19


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Basic Information Top
Gene Symbol:WDR19 ( DYF-2,FLJ23127,IFT144,KIAA1638,ORF26,Oseg6,PWDMP )
Gene Full Name: WD repeat domain 19
Band: 4p14
Quick LinksEntrez ID:57728; OMIM: 608151; Uniprot ID:WDR19_HUMAN; ENSEMBL ID: ENSG00000157796; HGNC ID: 18340
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst3 / 6231948
fetus19 / 56401233
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult49 / 193912125
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor5 / 9417853
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor3 / 26384511
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor10 / 96359103
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal101 / 336030730
ovarian tumor3 / 7668239
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood1 / 1234788
bone1 / 7165513
bone marrow0 / 488010 
brain31 / 110098928
cervix0 / 481710 
connective tissue9 / 14925560
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye4 / 21105418
heart0 / 896260 
intestine3 / 23447212
kidney4 / 21177718
larynx0 / 241450 
liver11 / 20774352
lung13 / 33697438
lymph0 / 442700 
lymph node2 / 9161021
mammary gland5 / 15327132
mouth0 / 670520 
muscle5 / 10771546
nerve1 / 1576863
ovary2 / 10205119
pancreas13 / 21481260
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland3 / 16585180
placenta0 / 2808250 
prostate3 / 18934515
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach0 / 966190 
testis12 / 33044236
thymus2 / 8113124
thyroid3 / 4747363
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus9 / 23287838
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220917_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.95
Adipocyte10.15
AdrenalCortex7.9
Adrenalgland6.2
Amygdala11.3
Appendix8.4
AtrioventricularNode6.2
BDCA4+_DentriticCells8.1
Bonemarrow7.05
BronchialEpithelialCells8.3
CD105+_Endothelial7.15
CD14+_Monocytes7.45
CD19+_BCells(neg._sel.)8.1
CD33+_Myeloid8.65
CD34+12.45
CD4+_Tcells9.65
CD56+_NKCells8.6
CD71+_EarlyErythroid6.55
CD8+_Tcells9.5
CardiacMyocytes9.1
Caudatenucleus12
Cerebellum5.85
CerebellumPeduncles8.4
CiliaryGanglion5.05
CingulateCortex8.05
Colorectaladenocarcinoma7.1
DorsalRootGanglion6.9
FetalThyroid30.65
Fetalbrain43.45
Fetalliver11.25
Fetallung49.9
GlobusPallidus6.6
Heart9.15
Hypothalamus26.05
Kidney6
Leukemia_chronicMyelogenousK-5626.25
Leukemia_promyelocytic-HL-6017.4
Leukemialymphoblastic(MOLT-4)10.2
Liver9.6
Lung7.8
Lymphnode9.75
Lymphoma_burkitts(Daudi)9.75
Lymphoma_burkitts(Raji)10.95
MedullaOblongata8.45
OccipitalLobe6.5
OlfactoryBulb11.6
Ovary7.1
Pancreas5.7
PancreaticIslet8.4
ParietalLobe7.4
Pituitary42.35
Placenta7.35
Pons7.3
PrefrontalCortex62.2
Prostate8.25
Salivarygland6
SkeletalMuscle8.25
Skin5.95
SmoothMuscle8.25
Spinalcord8
SubthalamicNucleus6.8
SuperiorCervicalGanglion8.65
TemporalLobe6.4
Testis12.95
TestisGermCell28.3
TestisIntersitial41.65
TestisLeydigCell12.25
TestisSeminiferousTubule28.65
Thalamus8.95
Thymus5.6
Thyroid37.85
Tongue6.9
Tonsil7.1
Trachea6.2
TrigeminalGanglion9.05
Uterus22.7
UterusCorpus6.85
WholeBlood7.75
Wholebrain6.1
colon7
pineal_day18.12
pineal_night13.74
retina9.125
small_intestine6.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P110135
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.54 ± 0.5
Basal Forebrain6.35 ± 0.27
Basal Part of Pons6.09 ± 0.3
Cerebellar Cortex6.39 ± 0.39
Cerebellar Nuclei5.87 ± 0.32
Claustrum6.53 ± 0.67
Epithalamus7.23 ± 0.54
Frontal Lobe6 ± 0.43
Globus Pallidus6 ± 0.46
Hypothalamus6.3 ± 0.17
Insula6.12 ± 0.47
Limbic Lobe6.39 ± 0.48
Mesencephalon6.25 ± 0.48
Myelencephalon6.22 ± 0.52
Occipital Lobe6.79 ± 0.48
Parietal Lobe6.33 ± 0.42
Pontine Tegmentum6.19 ± 0.44
Striatum6.29 ± 0.4
Subthalamus6.02 ± 0.29
Temporal Lobe6.09 ± 0.43
Thalamus6.03 ± 0.31
White Matter6.13 ± 0.45
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Wdr19CBCerebellum1.85
1.96
Wdr19CTXCerebral cortex6.18
4.06
Wdr19HIPHippocampal region10.32
9.64
Wdr19HPFHippocampal formation7.82
6.83
Wdr19HYHypothalamus0.27
0.24
Wdr19LSXLateral septal complex1.34
1.11
Wdr19MBMidbrain0.97
0.95
Wdr19MYMedulla2.11
2.41
Wdr19OLFOlfactory bulb10.37
7.1
Wdr19PPons2.73
2.95
Wdr19PALPallidum0.61
0.46
Wdr19RHPRetrohippocampal region3.74
2.95
Wdr19sAMYStriatum-like amygdalar nuclei1.25
0.94
Wdr19STRStriatum1.22
0.89
Wdr19STRdStriatum dorsal region0.74
0.57
Wdr19STRvStriatum ventral region2.56
1.65
Wdr19THThalamus1.34
1.21
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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