AutismKB 2.0

Annotation Detail for ANKRA2


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Basic Information Top
Gene Symbol:ANKRA2 ( ANKRA )
Gene Full Name: ankyrin repeat, family A (RFXANK-like), 2
Band: 5q13.2
Quick LinksEntrez ID:57763; OMIM: 605787; Uniprot ID:ANRA2_HUMAN; ENSEMBL ID: ENSG00000164331; HGNC ID: 13208
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst3 / 6231948
fetus17 / 56401230
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult57 / 193912129
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor1 / 3436629
chondrosarcoma4 / 8282348
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor7 / 26384526
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia4 / 9584241
liver tumor0 / 963590 
lung tumor3 / 10312729
lymphoma1 / 7175513
non-neoplasia1 / 9725010
normal99 / 336030729
ovarian tumor0 / 766820 
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer3 / 10268029
retinoblastoma1 / 4635621
skin tumor3 / 12494924
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood6 / 12347848
bone2 / 7165527
bone marrow1 / 4880120
brain32 / 110098929
cervix6 / 48171124
connective tissue3 / 14925520
ear1 / 1621261
embryonic tissue13 / 21572260
esophagus0 / 202090 
eye6 / 21105428
heart3 / 8962633
intestine2 / 2344728
kidney5 / 21177723
larynx0 / 241450 
liver2 / 2077439
lung19 / 33697456
lymph0 / 442700 
lymph node4 / 9161043
mammary gland4 / 15327126
mouth0 / 670520 
muscle4 / 10771537
nerve0 / 157680 
ovary0 / 1020510 
pancreas10 / 21481246
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland3 / 16585180
placenta12 / 28082542
prostate5 / 18934526
salivary gland0 / 201550 
skin6 / 21057428
spleen1 / 5395218
stomach3 / 9661931
testis7 / 33044221
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218769_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts23.05
Adipocyte17.4
AdrenalCortex17.25
Adrenalgland26.9
Amygdala25.7
Appendix20.5
AtrioventricularNode15.75
BDCA4+_DentriticCells30.2
Bonemarrow21
BronchialEpithelialCells25.9
CD105+_Endothelial21.5
CD14+_Monocytes21.1
CD19+_BCells(neg._sel.)39.55
CD33+_Myeloid31.45
CD34+41.8
CD4+_Tcells46.5
CD56+_NKCells87.4
CD71+_EarlyErythroid22.3
CD8+_Tcells55.1
CardiacMyocytes31.85
Caudatenucleus18.65
Cerebellum19.85
CerebellumPeduncles25.55
CiliaryGanglion17.4
CingulateCortex18.85
Colorectaladenocarcinoma14.85
DorsalRootGanglion20.85
FetalThyroid23.95
Fetalbrain51.3
Fetalliver19.95
Fetallung19.75
GlobusPallidus17.35
Heart27.7
Hypothalamus31.75
Kidney15.5
Leukemia_chronicMyelogenousK-56221.45
Leukemia_promyelocytic-HL-6018.1
Leukemialymphoblastic(MOLT-4)15.5
Liver22.65
Lung14.05
Lymphnode30.65
Lymphoma_burkitts(Daudi)28.85
Lymphoma_burkitts(Raji)20.95
MedullaOblongata21.8
OccipitalLobe18.4
OlfactoryBulb15.75
Ovary16.8
Pancreas11.05
PancreaticIslet17.8
ParietalLobe21.4
Pituitary28.65
Placenta20.6
Pons18.6
PrefrontalCortex23.2
Prostate57.85
Salivarygland22.55
SkeletalMuscle16.35
Skin20
SmoothMuscle21.65
Spinalcord34.9
SubthalamicNucleus16.15
SuperiorCervicalGanglion33.05
TemporalLobe27.4
Testis16.45
TestisGermCell14.4
TestisIntersitial13.8
TestisLeydigCell20.75
TestisSeminiferousTubule17.2
Thalamus17.1
Thymus15.35
Thyroid38.2
Tongue20.9
Tonsil16.9
Trachea17.05
TrigeminalGanglion29.6
Uterus22.8
UterusCorpus18.5
WholeBlood23.9
Wholebrain17.7
colon42.25
pineal_day42.88
pineal_night35.14
retina28.55
small_intestine57.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P41634
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.6 ± 0.42
Basal Forebrain6.95 ± 0.19
Basal Part of Pons6.6 ± 0.25
Cerebellar Cortex7.18 ± 0.15
Cerebellar Nuclei6.99 ± 0.28
Claustrum6.44 ± 0.35
Epithalamus7.28 ± 0.32
Frontal Lobe6.74 ± 0.33
Globus Pallidus7.07 ± 0.34
Hypothalamus7.15 ± 0.28
Insula6.77 ± 0.17
Limbic Lobe6.85 ± 0.24
Mesencephalon6.91 ± 0.27
Myelencephalon6.86 ± 0.32
Occipital Lobe7 ± 0.27
Parietal Lobe6.77 ± 0.28
Pontine Tegmentum6.95 ± 0.29
Striatum6.81 ± 0.3
Subthalamus6.63 ± 0.32
Temporal Lobe6.81 ± 0.27
Thalamus6.81 ± 0.3
White Matter7.84 ± 0.24
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ankra2CBCerebellum1.59
1.7
Ankra2CTXCerebral cortex20.94
7.26
Ankra2HIPHippocampal region11.94
8.43
Ankra2HPFHippocampal formation13.83
7.62
Ankra2HYHypothalamus0.77
0.31
Ankra2LSXLateral septal complex0.38
0.16
Ankra2MBMidbrain1.04
0.69
Ankra2MYMedulla1.71
1.36
Ankra2OLFOlfactory bulb14.89
7.18
Ankra2PPons1.12
0.68
Ankra2PALPallidum1.8
0.81
Ankra2RHPRetrohippocampal region17.4
6.8
Ankra2sAMYStriatum-like amygdalar nuclei4.55
1.34
Ankra2STRStriatum2.98
1.09
Ankra2STRdStriatum dorsal region3.22
1.25
Ankra2STRvStriatum ventral region2
0.75
Ankra2THThalamus1.61
1.29
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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