AutismKB 2.0

Annotation Detail for CCNB1IP1


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Basic Information Top
Gene Symbol:CCNB1IP1 ( C14orf18,HEI10 )
Gene Full Name: cyclin B1 interacting protein 1
Band: 14q11.2
Quick LinksEntrez ID:57820; OMIM: 608249; Uniprot ID:CIP1_HUMAN; ENSEMBL ID: ENSG00000100814; HGNC ID: 19437
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body14 / 70761197
blastocyst6 / 6231996
fetus42 / 56401274
neonate0 / 310970 
infant3 / 23620127
juvenile3 / 5555653
adult107 / 193912155
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma1 / 1747557
breast (mammary gland) tumor2 / 9417821
cervical tumor2 / 3436658
chondrosarcoma11 / 82823132
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor31 / 119369259
germ cell tumor19 / 26384572
glioma7 / 10688365
head and neck tumor11 / 13630280
kidney tumor3 / 6895943
leukemia4 / 9584241
liver tumor13 / 96359134
lung tumor26 / 103127252
lymphoma9 / 71755125
non-neoplasia10 / 97250102
normal167 / 336030749
ovarian tumor4 / 7668252
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS42 / 125680334
prostate cancer4 / 10268038
retinoblastoma19 / 46356409
skin tumor7 / 12494956
soft tissue/muscle tissue tumor16 / 125191127
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland4 / 33197120
ascites15 / 40015374
bladder1 / 2975733
blood4 / 12347832
bone14 / 71655195
bone marrow2 / 4880140
brain53 / 110098948
cervix5 / 48171103
connective tissue6 / 14925540
ear2 / 16212123
embryonic tissue45 / 215722208
esophagus0 / 202090 
eye23 / 211054108
heart9 / 89626100
intestine9 / 23447238
kidney10 / 21177747
larynx2 / 2414582
liver13 / 20774362
lung30 / 33697489
lymph7 / 44270158
lymph node4 / 9161043
mammary gland2 / 15327113
mouth3 / 6705244
muscle12 / 107715111
nerve1 / 1576863
ovary7 / 10205168
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta19 / 28082567
prostate5 / 18934526
salivary gland3 / 20155148
skin9 / 21057442
spleen1 / 5395218
stomach16 / 96619165
testis12 / 33044236
thymus1 / 8113112
thyroid7 / 47473147
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus7 / 23287830
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 217988_at
Cell line Expression level Expression bar
721_B_lymphoblasts100.7
Adipocyte10.2
AdrenalCortex9.15
Adrenalgland7.5
Amygdala7.1
Appendix8.9
AtrioventricularNode6.9
BDCA4+_DentriticCells64.8
Bonemarrow8.6
BronchialEpithelialCells50.5
CD105+_Endothelial9
CD14+_Monocytes9.9
CD19+_BCells(neg._sel.)105.35
CD33+_Myeloid13.65
CD34+170.65
CD4+_Tcells10.85
CD56+_NKCells22.4
CD71+_EarlyErythroid7.3
CD8+_Tcells21.5
CardiacMyocytes11.25
Caudatenucleus7.75
Cerebellum7.3
CerebellumPeduncles10.2
CiliaryGanglion6.35
CingulateCortex9.1
Colorectaladenocarcinoma9.1
DorsalRootGanglion7.35
FetalThyroid10.15
Fetalbrain16.55
Fetalliver7.8
Fetallung18.8
GlobusPallidus6.7
Heart7.9
Hypothalamus16.5
Kidney10.05
Leukemia_chronicMyelogenousK-562112.85
Leukemia_promyelocytic-HL-60113.2
Leukemialymphoblastic(MOLT-4)69.55
Liver10.45
Lung9.8
Lymphnode7.7
Lymphoma_burkitts(Daudi)96.6
Lymphoma_burkitts(Raji)330.7
MedullaOblongata9.85
OccipitalLobe8.5
OlfactoryBulb8.25
Ovary16.8
Pancreas20.15
PancreaticIslet16.6
ParietalLobe9.4
Pituitary10.35
Placenta8.55
Pons8.4
PrefrontalCortex12.25
Prostate10.5
Salivarygland8.9
SkeletalMuscle10.15
Skin7.7
SmoothMuscle10.35
Spinalcord9.5
SubthalamicNucleus8.75
SuperiorCervicalGanglion10.15
TemporalLobe7.95
Testis9.5
TestisGermCell11.45
TestisIntersitial9.15
TestisLeydigCell8.8
TestisSeminiferousTubule8.55
Thalamus9.25
Thymus6.85
Thyroid16.25
Tongue8.65
Tonsil9.3
Trachea7.45
TrigeminalGanglion9.2
Uterus17.8
UterusCorpus8.5
WholeBlood9.5
Wholebrain6.8
colon7.7
pineal_day12.42
pineal_night9.44
retina14.5
small_intestine7.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7401_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.03 ± 0.64
Basal Forebrain3.83 ± 0.21
Basal Part of Pons4.06 ± 0.54
Cerebellar Cortex3.9 ± 0.5
Cerebellar Nuclei4.33 ± 0.54
Claustrum4.34 ± 0.52
Epithalamus3.95 ± 0.38
Frontal Lobe3.97 ± 0.61
Globus Pallidus3.95 ± 0.76
Hypothalamus3.84 ± 0.74
Insula3.86 ± 0.48
Limbic Lobe4 ± 0.66
Mesencephalon3.96 ± 0.63
Myelencephalon4.01 ± 0.64
Occipital Lobe4.12 ± 0.56
Parietal Lobe3.92 ± 0.73
Pontine Tegmentum3.86 ± 0.59
Striatum4.1 ± 0.59
Subthalamus3.94 ± 0.51
Temporal Lobe3.84 ± 0.63
Thalamus4.05 ± 0.57
White Matter4.23 ± 0.47
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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