Annotation Detail for PTPN14
Basic Information Top
| Gene Symbol: | PTPN14 ( MGC126803,PEZ,PTP36 ) |
|---|---|
| Gene Full Name: | protein tyrosine phosphatase, non-receptor type 14 |
| Band: | 1q32.3-q41 |
| Quick Links | Entrez ID:5784; OMIM: 603155; Uniprot ID:PTN14_HUMAN; ENSEMBL ID: ENSG00000152104; HGNC ID: 9647 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.193557
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 7 / 70761 | 98 |  |
| blastocyst | 6 / 62319 | 96 | |
| fetus | 27 / 564012 | 47 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 3 / 55556 | 53 | |
| adult | 79 / 1939121 | 40 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 1 / 17475 | 57 | |
| breast (mammary gland) tumor | 7 / 94178 | 74 | |
| cervical tumor | 3 / 34366 | 87 | |
| chondrosarcoma | 6 / 82823 | 72 | |
| colorectal tumor | 6 / 114246 | 52 | |
| esophageal tumor | 2 / 17290 | 115 | |
| gastrointestinal tumor | 2 / 119369 | 16 | |
| germ cell tumor | 16 / 263845 | 60 | |
| glioma | 1 / 106883 | 9 |  |
| head and neck tumor | 1 / 136302 | 7 | |
| kidney tumor | 7 / 68959 | 101 | |
| leukemia | 1 / 95842 | 10 | |
| liver tumor | 7 / 96359 | 72 | |
| lung tumor | 6 / 103127 | 58 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 6 / 97250 | 61 | |
| normal | 116 / 3360307 | 34 | |
| ovarian tumor | 1 / 76682 | 13 | |
| pancreatic tumor | 2 / 104616 | 19 | |
| primitive neuroectodermal tumor of the CNS | 1 / 125680 | 7 | |
| prostate cancer | 1 / 102680 | 9 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 12 / 124949 | 96 | |
| soft tissue/muscle tissue tumor | 4 / 125191 | 31 | |
| uterine tumor | 11 / 90257 | 121 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 1 / 13106 | 76 | |
| adrenal gland | 1 / 33197 | 30 | |
| ascites | 2 / 40015 | 49 | |
| bladder | 1 / 29757 | 33 | |
| blood | 1 / 123478 | 8 | |
| bone | 3 / 71655 | 41 | |
| bone marrow | 1 / 48801 | 20 | |
| brain | 10 / 1100989 | 9 | |
| cervix | 3 / 48171 | 62 | |
| connective tissue | 11 / 149255 | 73 | |
| ear | 2 / 16212 | 123 | |
| embryonic tissue | 15 / 215722 | 69 | |
| esophagus | 2 / 20209 | 98 | |
| eye | 5 / 211054 | 23 | |
| heart | 4 / 89626 | 44 | |
| intestine | 7 / 234472 | 29 | |
| kidney | 9 / 211777 | 42 | |
| larynx | 0 / 24145 | 0 | |
| liver | 10 / 207743 | 48 | |
| lung | 19 / 336974 | 56 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 12 / 153271 | 78 | |
| mouth | 1 / 67052 | 14 | |
| muscle | 7 / 107715 | 64 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 4 / 102051 | 39 | |
| pancreas | 3 / 214812 | 13 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 1 / 41328 | 24 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 9 / 280825 | 32 | |
| prostate | 3 / 189345 | 15 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 19 / 210574 | 90 | |
| spleen | 1 / 53952 | 18 | |
| stomach | 0 / 96619 | 0 | |
| testis | 15 / 330442 | 45 | |
| thymus | 4 / 81131 | 49 | |
| thyroid | 1 / 47473 | 21 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 1 / 52413 | 19 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 18 / 232878 | 77 | |
| vascular | 1 / 51780 | 19 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 205503_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 5.8 | |
| Adipocyte | 4.75 | |
| AdrenalCortex | 5.2 | |
| Adrenalgland | 4.05 | |
| Amygdala | 5 | |
| Appendix | 5 | |
| AtrioventricularNode | 3.9 | |
| BDCA4+_DentriticCells | 4.95 | |
| Bonemarrow | 4.8 | |
| BronchialEpithelialCells | 4.75 | |
| CD105+_Endothelial | 4.75 | |
| CD14+_Monocytes | 5 | |
| CD19+_BCells(neg._sel.) | 5.05 | |
| CD33+_Myeloid | 5.85 | |
| CD34+ | 5.75 | |
| CD4+_Tcells | 4.95 | |
| CD56+_NKCells | 5.4 | |
| CD71+_EarlyErythroid | 4.45 | |
| CD8+_Tcells | 4.4 | |
| CardiacMyocytes | 6.65 | |
| Caudatenucleus | 4.25 | |
| Cerebellum | 3.85 | |
| CerebellumPeduncles | 5.45 | |
| CiliaryGanglion | 3.55 | |
| CingulateCortex | 4.9 | |
| Colorectaladenocarcinoma | 4.8 | |
| DorsalRootGanglion | 3.8 | |
| FetalThyroid | 4.7 | |
| Fetalbrain | 4.7 | |
| Fetalliver | 4.2 | |
| Fetallung | 3.9 | |
| GlobusPallidus | 3.6 | |
| Heart | 6.2 | |
| Hypothalamus | 5.1 | |
| Kidney | 3.95 | |
| Leukemia_chronicMyelogenousK-562 | 4.25 | |
| Leukemia_promyelocytic-HL-60 | 4.2 | |
| Leukemialymphoblastic(MOLT-4) | 3.75 | |
| Liver | 6.55 | |
| Lung | 5.25 | |
| Lymphnode | 4.1 | |
| Lymphoma_burkitts(Daudi) | 6.15 | |
| Lymphoma_burkitts(Raji) | 6.85 | |
| MedullaOblongata | 4.4 | |
| OccipitalLobe | 4.2 | |
| OlfactoryBulb | 3.8 | |
| Ovary | 3.2 | |
| Pancreas | 3.85 | |
| PancreaticIslet | 5.05 | |
| ParietalLobe | 5.1 | |
| Pituitary | 5.6 | |
| Placenta | 5.45 | |
| Pons | 4.55 | |
| PrefrontalCortex | 5.75 | |
| Prostate | 5.65 | |
| Salivarygland | 3.85 | |
| SkeletalMuscle | 5.95 | |
| Skin | 3.85 | |
| SmoothMuscle | 5.45 | |
| Spinalcord | 5.1 | |
| SubthalamicNucleus | 4.4 | |
| SuperiorCervicalGanglion | 5.85 | |
| TemporalLobe | 4.4 | |
| Testis | 4.15 | |
| TestisGermCell | 4.05 | |
| TestisIntersitial | 4 | |
| TestisLeydigCell | 4.75 | |
| TestisSeminiferousTubule | 4.1 | |
| Thalamus | 4.85 | |
| Thymus | 3.75 | |
| Thyroid | 5.9 | |
| Tongue | 4.8 | |
| Tonsil | 4.65 | |
| Trachea | 4 | |
| TrigeminalGanglion | 5 | |
| Uterus | 3.95 | |
| UterusCorpus | 4.5 | |
| WholeBlood | 5.25 | |
| Wholebrain | 4 | |
| colon | 4.8 | |
| pineal_day | 5.78 | |
| pineal_night | 5.72 | |
| retina | 5.7 | |
| small_intestine | 4.55 | |
- Probe name: A_24_P2648
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 7.06 ± 0.53 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 6.49 ± 0.42 | |
| Basal Part of Pons | 6.3 ± 0.27 | |
| Cerebellar Cortex | 6.18 ± 0.28 | |
| Cerebellar Nuclei | 6.99 ± 0.32 | |
| Claustrum | 6.09 ± 0.54 | |
| Epithalamus | 6.95 ± 0.32 | |
| Frontal Lobe | 6.68 ± 0.58 | |
| Globus Pallidus | 7.9 ± 0.36 | |
| Hypothalamus | 6.13 ± 0.41 | |
| Insula | 6.58 ± 0.57 | |
| Limbic Lobe | 6.91 ± 0.68 | |
| Mesencephalon | 6.94 ± 0.55 | |
| Myelencephalon | 6.81 ± 0.59 | |
| Occipital Lobe | 7.38 ± 0.55 | |
| Parietal Lobe | 7.11 ± 0.46 | |
| Pontine Tegmentum | 6.99 ± 0.64 | |
| Striatum | 6.43 ± 0.79 | |
| Subthalamus | 6.55 ± 0.28 | |
| Temporal Lobe | 6.81 ± 0.45 | |
| Thalamus | 6.81 ± 0.37 | |
| White Matter | 6.56 ± 0.41 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Ptpn14 | CB | Cerebellum | 36.58 | |
| 58.55 | | |||
| Ptpn14 | CTX | Cerebral cortex | 100 | |
| 90.25 | | |||
| Ptpn14 | HIP | Hippocampal region | 51.5 | |
| 79.61 | | |||
| Ptpn14 | HPF | Hippocampal formation | 62.18 | |
| 77.06 | | |||
| Ptpn14 | HY | Hypothalamus | 39.85 | |
| 33.65 | | |||
| Ptpn14 | LSX | Lateral septal complex | 47.02 | |
| 36.56 | | |||
| Ptpn14 | MB | Midbrain | 49.68 | |
| 49.91 | | |||
| Ptpn14 | MY | Medulla | 42.76 | |
| 51.32 | | |||
| Ptpn14 | OLF | Olfactory bulb | 79.2 | |
| 76.52 | | |||
| Ptpn14 | P | Pons | 40.75 | |
| 47.39 | | |||
| Ptpn14 | PAL | Pallidum | 32.39 | |
| 31.79 | | |||
| Ptpn14 | RHP | Retrohippocampal region | 82.68 | |
| 76.83 | | |||
| Ptpn14 | sAMY | Striatum-like amygdalar nuclei | 52.13 | |
| 44.1 | | |||
| Ptpn14 | STR | Striatum | 41.52 | |
| 32.51 | | |||
| Ptpn14 | STRd | Striatum dorsal region | 38.01 | |
| 29.65 | | |||
| Ptpn14 | STRv | Striatum ventral region | 47.31 | |
| 35.34 | | |||
| Ptpn14 | TH | Thalamus | 65.24 | |
| 63.94 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00130935 | 22 | 164 | 185 | EYVLFPMDLALEEAVLEELTQK | Peptide Atlas |
| PTN14_HUMAN_660 | 8 | 660 | 667 | SLHLPMAR | PRIDE |
| PTN14_HUMAN_731 | 13 | 731 | 743 | MEYSAQLQAALAR | PRIDE |
| PTN14_HUMAN_766 | 12 | 766 | 777 | QDQASLPPAMAR | PRIDE |
| PTN14_HUMAN_827 | 17 | 827 | 843 | ERPVSEMFSLEDSIIER | PRIDE |