AutismKB 2.0

Annotation Detail for ZNF410


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Basic Information Top
Gene Symbol:ZNF410 ( APA-1,APA1 )
Gene Full Name: zinc finger protein 410
Band: 14q24.3
Quick LinksEntrez ID:57862; OMIM: NA; Uniprot ID:ZN410_HUMAN; ENSEMBL ID: ENSG00000119725; HGNC ID: 20144
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst2 / 6231932
fetus57 / 564012101
neonate4 / 31097128
infant2 / 2362084
juvenile16 / 55556287
adult191 / 193912198
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma2 / 17475114
breast (mammary gland) tumor8 / 9417884
cervical tumor4 / 34366116
chondrosarcoma6 / 8282372
colorectal tumor6 / 11424652
esophageal tumor1 / 1729057
gastrointestinal tumor15 / 119369125
germ cell tumor34 / 263845128
glioma15 / 106883140
head and neck tumor3 / 13630222
kidney tumor9 / 68959130
leukemia11 / 95842114
liver tumor15 / 96359155
lung tumor12 / 103127116
lymphoma1 / 7175513
non-neoplasia14 / 97250143
normal439 / 3360307130
ovarian tumor3 / 7668239
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS31 / 125680246
prostate cancer6 / 10268058
retinoblastoma3 / 4635664
skin tumor13 / 124949104
soft tissue/muscle tissue tumor21 / 125191167
uterine tumor17 / 90257188
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland6 / 33197180
ascites6 / 40015149
bladder8 / 29757268
blood31 / 123478251
bone2 / 7165527
bone marrow4 / 4880181
brain164 / 1100989148
cervix8 / 48171166
connective tissue32 / 149255214
ear0 / 162120 
embryonic tissue13 / 21572260
esophagus2 / 2020998
eye14 / 21105466
heart8 / 8962689
intestine20 / 23447285
kidney26 / 211777122
larynx0 / 241450 
liver24 / 207743115
lung42 / 336974124
lymph0 / 442700 
lymph node8 / 9161087
mammary gland21 / 153271137
mouth4 / 6705259
muscle1 / 1077159
nerve0 / 157680 
ovary6 / 10205158
pancreas11 / 21481251
parathyroid1 / 2053948
pharynx14 / 41328338
pituitary gland0 / 165850 
placenta15 / 28082553
prostate20 / 189345105
salivary gland3 / 20155148
skin23 / 210574109
spleen22 / 53952407
stomach11 / 96619113
testis62 / 330442187
thymus13 / 81131160
thyroid3 / 4747363
tonsil2 / 16999117
trachea7 / 52413133
umbilical cord0 / 136800 
uterus56 / 232878240
vascular15 / 51780289
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209944_at
Cell line Expression level Expression bar
721_B_lymphoblasts152.4
Adipocyte30.95
AdrenalCortex68.5
Adrenalgland56.35
Amygdala20.45
Appendix6.8
AtrioventricularNode5.35
BDCA4+_DentriticCells81.25
Bonemarrow57.1
BronchialEpithelialCells123.55
CD105+_Endothelial78.05
CD14+_Monocytes145.4
CD19+_BCells(neg._sel.)163.2
CD33+_Myeloid92.95
CD34+161
CD4+_Tcells59.55
CD56+_NKCells181.75
CD71+_EarlyErythroid75.5
CD8+_Tcells57.85
CardiacMyocytes13.75
Caudatenucleus22.15
Cerebellum16.95
CerebellumPeduncles7.5
CiliaryGanglion4.4
CingulateCortex27.55
Colorectaladenocarcinoma26.25
DorsalRootGanglion7
FetalThyroid52.7
Fetalbrain41.55
Fetalliver18.9
Fetallung64.4
GlobusPallidus4.25
Heart7.5
Hypothalamus44.1
Kidney24.25
Leukemia_chronicMyelogenousK-56263.4
Leukemia_promyelocytic-HL-6035.95
Leukemialymphoblastic(MOLT-4)64.2
Liver7.15
Lung34.95
Lymphnode46.4
Lymphoma_burkitts(Daudi)40.95
Lymphoma_burkitts(Raji)9.45
MedullaOblongata22.3
OccipitalLobe24.15
OlfactoryBulb70.4
Ovary18.35
Pancreas27.65
PancreaticIslet56.55
ParietalLobe6.9
Pituitary43.85
Placenta140.95
Pons6.9
PrefrontalCortex83.55
Prostate42.15
Salivarygland22.1
SkeletalMuscle6.65
Skin15.05
SmoothMuscle57.4
Spinalcord33.8
SubthalamicNucleus4.9
SuperiorCervicalGanglion7.1
TemporalLobe6.45
Testis394.25
TestisGermCell233.85
TestisIntersitial305.95
TestisLeydigCell135.55
TestisSeminiferousTubule116.9
Thalamus27.8
Thymus91.65
Thyroid48.85
Tongue6.55
Tonsil32.15
Trachea24.3
TrigeminalGanglion21.25
Uterus53.55
UterusCorpus22.15
WholeBlood106.65
Wholebrain15.35
colon36.75
pineal_day69.32
pineal_night57.32
retina100.45
small_intestine76.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6061_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.3 ± 0.59
Basal Forebrain5.12 ± 0.41
Basal Part of Pons5.35 ± 0.17
Cerebellar Cortex5.25 ± 0.39
Cerebellar Nuclei5.07 ± 0.46
Claustrum4.88 ± 0.63
Epithalamus5.24 ± 0.41
Frontal Lobe5.14 ± 0.37
Globus Pallidus5.37 ± 0.27
Hypothalamus5.23 ± 0.23
Insula5.09 ± 0.21
Limbic Lobe5.04 ± 0.4
Mesencephalon5.08 ± 0.4
Myelencephalon5.09 ± 0.43
Occipital Lobe4.98 ± 0.38
Parietal Lobe5.09 ± 0.36
Pontine Tegmentum5.1 ± 0.4
Striatum4.93 ± 0.32
Subthalamus4.64 ± 0.54
Temporal Lobe5.17 ± 0.43
Thalamus5.03 ± 0.44
White Matter5.87 ± 0.29
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Zfp410CBCerebellum5.4
5.69
Zfp410CTXCerebral cortex26.22
17.52
Zfp410HIPHippocampal region27.88
28.07
Zfp410HPFHippocampal formation27.38
24.2
Zfp410HYHypothalamus17.27
13.39
Zfp410LSXLateral septal complex6.12
4.48
Zfp410MBMidbrain8.72
8.23
Zfp410MYMedulla8.93
11.58
Zfp410OLFOlfactory bulb32.48
25.98
Zfp410PPons15.67
18.07
Zfp410PALPallidum13.66
11.63
Zfp410RHPRetrohippocampal region27.04
19.09
Zfp410sAMYStriatum-like amygdalar nuclei17.49
11.84
Zfp410STRStriatum9.91
6.93
Zfp410STRdStriatum dorsal region8.94
6.27
Zfp410STRvStriatum ventral region12.21
8.37
Zfp410THThalamus19.66
14.37
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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