AutismKB 2.0

Annotation Detail for PTPRC


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Basic Information Top
Gene Symbol:PTPRC ( B220,CD45,CD45R,GP180,LCA,LY5,T200 )
Gene Full Name: protein tyrosine phosphatase, receptor type, C
Band: 1q31.3-q32.1
Quick LinksEntrez ID:5788; OMIM: 151460; Uniprot ID:PTPRC_HUMAN; ENSEMBL ID: ENSG00000081237; HGNC ID: 9666
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus24 / 56401242
neonate8 / 31097257
infant0 / 236200 
juvenile7 / 55556125
adult179 / 193912192
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma8 / 8282396
colorectal tumor6 / 11424652
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor3 / 26384511
glioma2 / 10688318
head and neck tumor3 / 13630222
kidney tumor1 / 6895914
leukemia18 / 95842187
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma31 / 71755432
non-neoplasia5 / 9725051
normal293 / 336030787
ovarian tumor2 / 7668226
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor101 / 125191806
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland2 / 3319760
ascites0 / 400150 
bladder0 / 297570 
blood90 / 123478728
bone2 / 7165527
bone marrow5 / 48801102
brain16 / 110098914
cervix0 / 481710 
connective tissue112 / 149255750
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine9 / 23447238
kidney3 / 21177714
larynx3 / 24145124
liver2 / 2077439
lung17 / 33697450
lymph5 / 44270112
lymph node64 / 91610698
mammary gland6 / 15327139
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary2 / 10205119
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx33 / 41328798
pituitary gland0 / 165850 
placenta6 / 28082521
prostate5 / 18934526
salivary gland0 / 201550 
skin2 / 2105749
spleen34 / 53952630
stomach8 / 9661982
testis2 / 3304426
thymus52 / 81131640
thyroid0 / 474730 
tonsil2 / 16999117
trachea5 / 5241395
umbilical cord0 / 136800 
uterus5 / 23287821
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212588_at
Cell line Expression level Expression bar
721_B_lymphoblasts147.2
Adipocyte6.45
AdrenalCortex7.5
Adrenalgland6
Amygdala7.05
Appendix10.45
AtrioventricularNode8.75
BDCA4+_DentriticCells1353.05
Bonemarrow54.45
BronchialEpithelialCells6.2
CD105+_Endothelial76.1
CD14+_Monocytes1801.65
CD19+_BCells(neg._sel.)1362.7
CD33+_Myeloid3340.65
CD34+652.55
CD4+_Tcells2319.4
CD56+_NKCells3837.55
CD71+_EarlyErythroid14.55
CD8+_Tcells2069.45
CardiacMyocytes9.85
Caudatenucleus6.05
Cerebellum5.5
CerebellumPeduncles8.05
CiliaryGanglion5.85
CingulateCortex7.15
Colorectaladenocarcinoma6.4
DorsalRootGanglion6.4
FetalThyroid6.8
Fetalbrain5.95
Fetalliver7.9
Fetallung51.5
GlobusPallidus5.4
Heart9.95
Hypothalamus9.55
Kidney6
Leukemia_chronicMyelogenousK-562507.65
Leukemia_promyelocytic-HL-60332.4
Leukemialymphoblastic(MOLT-4)206.5
Liver9
Lung7.3
Lymphnode923.5
Lymphoma_burkitts(Daudi)298.2
Lymphoma_burkitts(Raji)393.95
MedullaOblongata6.1
OccipitalLobe5.75
OlfactoryBulb7.9
Ovary4.95
Pancreas5.75
PancreaticIslet7.4
ParietalLobe7.05
Pituitary7.95
Placenta5.85
Pons6.7
PrefrontalCortex7.95
Prostate9.9
Salivarygland93.6
SkeletalMuscle9.25
Skin6.1
SmoothMuscle7.45
Spinalcord13.05
SubthalamicNucleus6.5
SuperiorCervicalGanglion8.8
TemporalLobe6.35
Testis5.35
TestisGermCell5.05
TestisIntersitial5.7
TestisLeydigCell7
TestisSeminiferousTubule5.75
Thalamus7.1
Thymus211.45
Thyroid10.7
Tongue6.8
Tonsil531.35
Trachea8.65
TrigeminalGanglion10.7
Uterus6.7
UterusCorpus6.55
WholeBlood3258.9
Wholebrain5.25
colon8.2
pineal_day8.28
pineal_night8.12
retina9.625
small_intestine10.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P12392
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.8 ± 0.94
Basal Forebrain2.19 ± 0.7
Basal Part of Pons2.81 ± 0.58
Cerebellar Cortex1.77 ± 0.47
Cerebellar Nuclei3.55 ± 0.8
Claustrum2.81 ± 0.76
Epithalamus4.19 ± 0.67
Frontal Lobe2.32 ± 0.81
Globus Pallidus4.34 ± 0.3
Hypothalamus2.62 ± 1.36
Insula2.49 ± 0.78
Limbic Lobe2.19 ± 0.81
Mesencephalon2.64 ± 0.83
Myelencephalon2.4 ± 0.88
Occipital Lobe2.03 ± 0.81
Parietal Lobe2.21 ± 0.93
Pontine Tegmentum2.3 ± 0.97
Striatum2.99 ± 0.83
Subthalamus3.31 ± 0.22
Temporal Lobe2.41 ± 0.97
Thalamus2.34 ± 0.77
White Matter4.62 ± 0.75
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
B1ALS2_HUMAN_0 0 0 0 LFLAEFQSIPR PRIDE
B1ALS2_HUMAN_1038 13 1038 1050 ETIGDFWQMIFQR PRIDE
B1ALS2_HUMAN_1054 9 1054 1062 VIVMLTELK PRIDE
B1ALS2_HUMAN_1063 15 1063 1077 HGDQEICAQYWGEGK PRIDE
B1ALS2_HUMAN_1133 10 1133 1142 ELISMIQVVK PRIDE
B1ALS2_HUMAN_1159 9 1159 1167 STPLLIHCR PRIDE
B1ALS2_HUMAN_303 11 303 313 FQLHDCTQVEK PRIDE
B1ALS2_HUMAN_339 11 339 349 FQCGNMIFDNK PRIDE
B1ALS2_HUMAN_381 18 381 398 IIKTDFGSPGEPQIIFCR PRIDE
B1ALS2_HUMAN_384 15 384 398 TDFGSPGEPQIIFCR PRIDE
B1ALS2_HUMAN_399 16 399 414 SEAAHQGVITWNPPQR PRIDE
B1ALS2_HUMAN_441 11 441 451 YDLQNLKPYTK PRIDE
B1ALS2_HUMAN_540 11 540 550 DLQYSTDYTFK PRIDE
B1ALS2_HUMAN_595 9 595 603 VLYKIYDLH PRIDE
B1ALS2_HUMAN_606 13 606 618 SCNLDEQQELVER PRIDE
B1ALS2_HUMAN_606 17 606 622 SCNLDEQQELVERDDEK PRIDE
B1ALS2_HUMAN_623 18 623 640 QLMNVEPIHADILLETYK PRIDE
B1ALS2_HUMAN_623 19 623 641 QLMNVEPIHADILLETYKR PRIDE
B1ALS2_HUMAN_649 11 649 659 LFLAEFQSIPR PRIDE
B1ALS2_HUMAN_660 11 660 670 VFSKFPIKEAR PRIDE
B1ALS2_HUMAN_680 11 680 690 YVDILPYDYNR PRIDE
B1ALS2_HUMAN_719 17 719 735 YIAAQGPRDETVDDFWR PRIDE
B1ALS2_HUMAN_727 9 727 735 DETVDDFWR PRIDE
B1ALS2_HUMAN_742 9 742 750 ATVIVMVTR PRIDE
B1ALS2_HUMAN_759 13 759 771 CAEYWPSMEEGTR PRIDE
B1ALS2_HUMAN_772 8 772 779 AFGDVVVK PRIDE
B1ALS2_HUMAN_786 8 786 793 CPDYIIQK PRIDE
B1ALS2_HUMAN_807 24 807 830 EVTHIQFTSWPDHGVPEDPHLLLK PRIDE
B1ALS2_HUMAN_835 22 835 856 VNAFSNFFSGPIVVHCSAGVGR PRIDE
B1ALS2_HUMAN_931 17 931 947 KRDPPSEPSPLEAEFQR PRIDE
B1ALS2_HUMAN_932 16 932 947 RDPPSEPSPLEAEFQR PRIDE
B1ALS2_HUMAN_933 15 933 947 DPPSEPSPLEAEFQR PRIDE
B1ALS2_HUMAN_936 13 936 948 PSEPSPLEAEFQR PRIDE
B1ALS2_HUMAN_971 11 971 981 NSNVIPYDYNR PRIDE
B1ALS2_HUMAN_982 11 982 992 VPLKHELEMSK PRIDE
PAp00002286 24 810 833 EVTHIQFTSWPDHGVPEDPHLLLK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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