AutismKB 2.0

Annotation Detail for PTPRD


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Basic Information Top
Gene Symbol:PTPRD ( HPTP,HPTPD,HPTPDELTA,MGC119750,MGC119751,MGC119752,MGC119753,PTPD,RPTPDELTA )
Gene Full Name: protein tyrosine phosphatase, receptor type, D
Band: 9p24.1-p23
Quick LinksEntrez ID:5789; OMIM: 601598; Uniprot ID:PTPRD_HUMAN; ENSEMBL ID: ENSG00000153707; HGNC ID: 9668
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst1 / 6231916
fetus49 / 56401286
neonate1 / 3109732
infant1 / 2362042
juvenile0 / 555560 
adult89 / 193912145
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor15 / 26384556
glioma2 / 10688318
head and neck tumor4 / 13630229
kidney tumor4 / 6895958
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal193 / 336030757
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor9 / 12519171
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain90 / 110098981
cervix0 / 481710 
connective tissue3 / 14925520
ear2 / 16212123
embryonic tissue14 / 21572264
esophagus0 / 202090 
eye7 / 21105433
heart4 / 8962644
intestine4 / 23447217
kidney19 / 21177789
larynx3 / 24145124
liver7 / 20774333
lung8 / 33697423
lymph0 / 442700 
lymph node0 / 916100 
mammary gland4 / 15327126
mouth2 / 6705229
muscle2 / 10771518
nerve0 / 157680 
ovary1 / 1020519
pancreas3 / 21481213
parathyroid12 / 20539584
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta4 / 28082514
prostate2 / 18934510
salivary gland0 / 201550 
skin1 / 2105744
spleen1 / 5395218
stomach1 / 9661910
testis9 / 33044227
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205712_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.35
Adipocyte6
AdrenalCortex6.5
Adrenalgland5.55
Amygdala8.85
Appendix6.95
AtrioventricularNode5.25
BDCA4+_DentriticCells6.25
Bonemarrow6.5
BronchialEpithelialCells5.95
CD105+_Endothelial6.05
CD14+_Monocytes6.5
CD19+_BCells(neg._sel.)6.55
CD33+_Myeloid7.6
CD34+7.45
CD4+_Tcells6.45
CD56+_NKCells7.3
CD71+_EarlyErythroid5.75
CD8+_Tcells5.75
CardiacMyocytes7.75
Caudatenucleus5.65
Cerebellum9.45
CerebellumPeduncles11.6
CiliaryGanglion4.6
CingulateCortex7.05
Colorectaladenocarcinoma6.1
DorsalRootGanglion5.2
FetalThyroid6.05
Fetalbrain11.2
Fetalliver5.5
Fetallung5.2
GlobusPallidus4.95
Heart10
Hypothalamus9.7
Kidney5.55
Leukemia_chronicMyelogenousK-5625.6
Leukemia_promyelocytic-HL-605.45
Leukemialymphoblastic(MOLT-4)4.95
Liver9.05
Lung6.7
Lymphnode5.25
Lymphoma_burkitts(Daudi)8.1
Lymphoma_burkitts(Raji)8.7
MedullaOblongata10.55
OccipitalLobe14.25
OlfactoryBulb4.9
Ovary4.35
Pancreas5.05
PancreaticIslet6.65
ParietalLobe8.3
Pituitary7.4
Placenta6.1
Pons6.05
PrefrontalCortex11.1
Prostate7.15
Salivarygland5.4
SkeletalMuscle8.4
Skin6.2
SmoothMuscle6.95
Spinalcord8.9
SubthalamicNucleus5.75
SuperiorCervicalGanglion8.4
TemporalLobe5.7
Testis5.35
TestisGermCell5.15
TestisIntersitial5.15
TestisLeydigCell6.25
TestisSeminiferousTubule5.35
Thalamus6.35
Thymus4.8
Thyroid7.6
Tongue6.6
Tonsil6.4
Trachea5.2
TrigeminalGanglion6.35
Uterus5.05
UterusCorpus7.8
WholeBlood6.75
Wholebrain5.35
colon6.15
pineal_day7.56
pineal_night7.46
retina8.925
small_intestine5.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_13909_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.38 ± 0.55
Basal Forebrain8.47 ± 0.22
Basal Part of Pons8.9 ± 0.42
Cerebellar Cortex8.65 ± 0.19
Cerebellar Nuclei8.85 ± 0.22
Claustrum7.85 ± 0.56
Epithalamus7.92 ± 0.64
Frontal Lobe8.46 ± 0.39
Globus Pallidus8.76 ± 0.33
Hypothalamus8.39 ± 0.23
Insula8.36 ± 0.22
Limbic Lobe8.36 ± 0.47
Mesencephalon8.39 ± 0.53
Myelencephalon8.48 ± 0.4
Occipital Lobe9.03 ± 0.46
Parietal Lobe8.65 ± 0.36
Pontine Tegmentum8.49 ± 0.41
Striatum7.91 ± 0.33
Subthalamus8.53 ± 0.31
Temporal Lobe8.48 ± 0.34
Thalamus8.76 ± 0.31
White Matter10.25 ± 0.31
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
PtprdCBCerebellum12.21
10.1
PtprdCTXCerebral cortex67.57
52.41
PtprdHIPHippocampal region41.7
37
PtprdHPFHippocampal formation52.34
47.56
PtprdHYHypothalamus24.62
19.69
PtprdLSXLateral septal complex15.5
11.99
PtprdMBMidbrain24.7
21.49
PtprdMYMedulla38.75
38.87
PtprdOLFOlfactory bulb78.12
79.35
PtprdPPons35.75
33.98
PtprdPALPallidum28.01
26.87
PtprdRHPRetrohippocampal region68.26
60.31
PtprdsAMYStriatum-like amygdalar nuclei26.19
20.45
PtprdSTRStriatum15.85
12.5
PtprdSTRdStriatum dorsal region14.76
11.85
PtprdSTRvStriatum ventral region13.76
10.29
PtprdTHThalamus33.09
33.55
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00043353 20 1360 1379 YQYFVVDPMAEYNMPQYILR Peptide Atlas
PTPRD_HUMAN_1089 10 1089 1098 GNSAGGLQHR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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