AutismKB 2.0

Annotation Detail for PTPRF


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Basic Information Top
Gene Symbol:PTPRF ( FLJ43335,FLJ45062,FLJ45567,LAR )
Gene Full Name: protein tyrosine phosphatase, receptor type, F
Band: 1p34.2
Quick LinksEntrez ID:5792; OMIM: 179590; Uniprot ID:PTPRF_HUMAN; ENSEMBL ID: ENSG00000142949; HGNC ID: 9670
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body10 / 70761141
blastocyst27 / 62319433
fetus77 / 564012136
neonate7 / 31097225
infant1 / 2362042
juvenile6 / 55556107
adult295 / 1939121152
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma9 / 17475515
breast (mammary gland) tumor18 / 94178191
cervical tumor0 / 343660 
chondrosarcoma14 / 82823169
colorectal tumor43 / 114246376
esophageal tumor0 / 172900 
gastrointestinal tumor9 / 11936975
germ cell tumor43 / 263845162
glioma12 / 106883112
head and neck tumor35 / 136302256
kidney tumor17 / 68959246
leukemia1 / 9584210
liver tumor10 / 96359103
lung tumor23 / 103127223
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal387 / 3360307115
ovarian tumor15 / 76682195
pancreatic tumor14 / 104616133
primitive neuroectodermal tumor of the CNS17 / 125680135
prostate cancer18 / 102680175
retinoblastoma13 / 46356280
skin tumor2 / 12494916
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor30 / 90257332
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue4 / 13106305
adrenal gland0 / 331970 
ascites5 / 40015124
bladder13 / 29757436
blood1 / 1234788
bone12 / 71655167
bone marrow2 / 4880140
brain110 / 110098999
cervix1 / 4817120
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue67 / 215722310
esophagus0 / 202090 
eye36 / 211054170
heart6 / 8962666
intestine59 / 234472251
kidney27 / 211777127
larynx7 / 24145289
liver14 / 20774367
lung56 / 336974166
lymph0 / 442700 
lymph node0 / 916100 
mammary gland31 / 153271202
mouth22 / 67052328
muscle14 / 107715129
nerve6 / 15768380
ovary27 / 102051264
pancreas23 / 214812107
parathyroid2 / 2053997
pharynx4 / 4132896
pituitary gland0 / 165850 
placenta56 / 280825199
prostate31 / 189345163
salivary gland0 / 201550 
skin8 / 21057437
spleen2 / 5395237
stomach3 / 9661931
testis42 / 330442127
thymus5 / 8113161
thyroid4 / 4747384
tonsil0 / 169990 
trachea12 / 52413228
umbilical cord13 / 13680950
uterus40 / 232878171
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 200635_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.15
Adipocyte9.85
AdrenalCortex8.65
Adrenalgland6.8
Amygdala8.6
Appendix7.9
AtrioventricularNode6.2
BDCA4+_DentriticCells7.4
Bonemarrow7.6
BronchialEpithelialCells20.65
CD105+_Endothelial7.55
CD14+_Monocytes7.4
CD19+_BCells(neg._sel.)7.7
CD33+_Myeloid9.3
CD34+8.85
CD4+_Tcells7.6
CD56+_NKCells8.25
CD71+_EarlyErythroid7.25
CD8+_Tcells6.75
CardiacMyocytes10.8
Caudatenucleus7.4
Cerebellum6.35
CerebellumPeduncles9.05
CiliaryGanglion5.45
CingulateCortex10.7
Colorectaladenocarcinoma7.85
DorsalRootGanglion5.9
FetalThyroid12.15
Fetalbrain8.5
Fetalliver6.95
Fetallung6.3
GlobusPallidus5.85
Heart10.45
Hypothalamus8.65
Kidney6.75
Leukemia_chronicMyelogenousK-5626.95
Leukemia_promyelocytic-HL-606.65
Leukemialymphoblastic(MOLT-4)5.75
Liver14.95
Lung13.3
Lymphnode6.1
Lymphoma_burkitts(Daudi)9.8
Lymphoma_burkitts(Raji)10.65
MedullaOblongata7.1
OccipitalLobe7.75
OlfactoryBulb6.2
Ovary4.8
Pancreas7.7
PancreaticIslet8.55
ParietalLobe8.75
Pituitary9
Placenta77.45
Pons8.05
PrefrontalCortex16.55
Prostate55.2
Salivarygland6.25
SkeletalMuscle9.5
Skin6.5
SmoothMuscle17.25
Spinalcord8.8
SubthalamicNucleus7.6
SuperiorCervicalGanglion8.6
TemporalLobe7.25
Testis6.5
TestisGermCell5.9
TestisIntersitial6.35
TestisLeydigCell7.75
TestisSeminiferousTubule6.45
Thalamus7.9
Thymus9.3
Thyroid12.35
Tongue8.9
Tonsil9.15
Trachea13.3
TrigeminalGanglion7.8
Uterus9.95
UterusCorpus7.35
WholeBlood7.95
Wholebrain7.75
colon29.65
pineal_day9.38
pineal_night9.26
retina9.75
small_intestine29.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P200984
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.4 ± 0.56
Basal Forebrain4.04 ± 0.34
Basal Part of Pons3.94 ± 0.58
Cerebellar Cortex3.52 ± 0.59
Cerebellar Nuclei3.64 ± 0.46
Claustrum3.89 ± 0.79
Epithalamus4.19 ± 0.81
Frontal Lobe3.97 ± 0.57
Globus Pallidus4.26 ± 0.5
Hypothalamus3.65 ± 0.62
Insula4.18 ± 0.24
Limbic Lobe3.98 ± 0.68
Mesencephalon3.98 ± 0.59
Myelencephalon4.01 ± 0.62
Occipital Lobe3.69 ± 0.56
Parietal Lobe3.89 ± 0.61
Pontine Tegmentum3.91 ± 0.69
Striatum3.97 ± 0.68
Subthalamus3.42 ± 0.8
Temporal Lobe4.08 ± 0.6
Thalamus4.04 ± 0.58
White Matter4.55 ± 0.31
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00007100 28 189 216 SGALQIESSEESDQGKYECVATNSAGTR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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