AutismKB 2.0

Annotation Detail for PTPRG


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Basic Information Top
Gene Symbol:PTPRG ( HPTPG,PTPG,R-PTP-GAMMA,RPTPG )
Gene Full Name: protein tyrosine phosphatase, receptor type, G
Band: 3p14.2
Quick LinksEntrez ID:5793; OMIM: 176886; Uniprot ID:PTPRG_HUMAN; ENSEMBL ID: ENSG00000144724; HGNC ID: 9671
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst10 / 62319160
fetus13 / 56401223
neonate1 / 3109732
infant0 / 236200 
juvenile1 / 5555617
adult44 / 193912122
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor5 / 26384518
glioma0 / 1068830 
head and neck tumor4 / 13630229
kidney tumor0 / 689590 
leukemia3 / 9584231
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal85 / 336030725
ovarian tumor7 / 7668291
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone5 / 7165569
bone marrow0 / 488010 
brain22 / 110098919
cervix0 / 481710 
connective tissue0 / 1492550 
ear1 / 1621261
embryonic tissue15 / 21572269
esophagus0 / 202090 
eye5 / 21105423
heart1 / 8962611
intestine3 / 23447212
kidney6 / 21177728
larynx0 / 241450 
liver1 / 2077434
lung6 / 33697417
lymph0 / 442700 
lymph node4 / 9161043
mammary gland2 / 15327113
mouth0 / 670520 
muscle1 / 1077159
nerve1 / 1576863
ovary8 / 10205178
pancreas3 / 21481213
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta11 / 28082539
prostate3 / 18934515
salivary gland0 / 201550 
skin4 / 21057418
spleen0 / 539520 
stomach2 / 9661920
testis12 / 33044236
thymus0 / 811310 
thyroid4 / 4747384
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204944_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.65
Adipocyte100.25
AdrenalCortex6.15
Adrenalgland4.65
Amygdala6.25
Appendix14.75
AtrioventricularNode4.6
BDCA4+_DentriticCells5.5
Bonemarrow5.35
BronchialEpithelialCells5.95
CD105+_Endothelial5.35
CD14+_Monocytes5.6
CD19+_BCells(neg._sel.)5.6
CD33+_Myeloid6.7
CD34+6.7
CD4+_Tcells5.5
CD56+_NKCells6.15
CD71+_EarlyErythroid5
CD8+_Tcells4.9
CardiacMyocytes7.25
Caudatenucleus4.75
Cerebellum4.3
CerebellumPeduncles6.15
CiliaryGanglion4.35
CingulateCortex5.45
Colorectaladenocarcinoma5.25
DorsalRootGanglion4.35
FetalThyroid5.15
Fetalbrain5.4
Fetalliver4.65
Fetallung4.4
GlobusPallidus3.95
Heart7.45
Hypothalamus5.75
Kidney4.45
Leukemia_chronicMyelogenousK-5624.7
Leukemia_promyelocytic-HL-604.7
Leukemialymphoblastic(MOLT-4)4.1
Liver7.35
Lung5.8
Lymphnode4.45
Lymphoma_burkitts(Daudi)6.85
Lymphoma_burkitts(Raji)7.65
MedullaOblongata4.9
OccipitalLobe4.7
OlfactoryBulb4.2
Ovary5.2
Pancreas4.35
PancreaticIslet5.7
ParietalLobe5.75
Pituitary6.2
Placenta5.7
Pons5.05
PrefrontalCortex6.65
Prostate6.15
Salivarygland4.3
SkeletalMuscle6.95
Skin4.4
SmoothMuscle6.05
Spinalcord5.65
SubthalamicNucleus4.9
SuperiorCervicalGanglion7.05
TemporalLobe4.85
Testis5.1
TestisGermCell16.15
TestisIntersitial4.45
TestisLeydigCell5.25
TestisSeminiferousTubule4.6
Thalamus5.4
Thymus4.05
Thyroid6.75
Tongue5.45
Tonsil5.15
Trachea4.45
TrigeminalGanglion5.8
Uterus4.3
UterusCorpus5.15
WholeBlood5.75
Wholebrain4.45
colon5.4
pineal_day6.56
pineal_night6.52
retina8.4
small_intestine5.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9135_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.53 ± 0.47
Basal Forebrain4 ± 0.4
Basal Part of Pons3.48 ± 0.41
Cerebellar Cortex4.19 ± 0.55
Cerebellar Nuclei3.87 ± 0.56
Claustrum4.06 ± 0.72
Epithalamus4.31 ± 0.38
Frontal Lobe4.13 ± 0.53
Globus Pallidus3.52 ± 0.62
Hypothalamus4.27 ± 0.51
Insula4.49 ± 0.38
Limbic Lobe4.6 ± 0.68
Mesencephalon4.28 ± 0.48
Myelencephalon4.36 ± 0.64
Occipital Lobe4.66 ± 0.53
Parietal Lobe4.27 ± 0.55
Pontine Tegmentum4.29 ± 0.58
Striatum4.54 ± 0.46
Subthalamus3.87 ± 0.34
Temporal Lobe4.38 ± 0.48
Thalamus4.04 ± 0.51
White Matter2.53 ± 1.05
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
PtprgCBCerebellum2.74
2.84
PtprgCTXCerebral cortex19.4
17.46
PtprgHIPHippocampal region26.23
45.6
PtprgHPFHippocampal formation28.99
40.94
PtprgHYHypothalamus6.13
5.66
PtprgLSXLateral septal complex12.87
10.51
PtprgMBMidbrain3.31
3.05
PtprgMYMedulla6.12
6.24
PtprgOLFOlfactory bulb30.81
28.51
PtprgPPons4.32
4.63
PtprgPALPallidum12.04
11.05
PtprgRHPRetrohippocampal region34.49
36.07
PtprgsAMYStriatum-like amygdalar nuclei13.55
11.54
PtprgSTRStriatum9
7.74
PtprgSTRdStriatum dorsal region6.23
5.81
PtprgSTRvStriatum ventral region15.01
11.15
PtprgTHThalamus6.18
8.33
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00027651 15 433 447 SDFSQTMLFQANTTR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018