AutismKB 2.0

Annotation Detail for PTPRJ


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Basic Information Top
Gene Symbol:PTPRJ ( CD148,DEP1,HPTPeta,R-PTP-ETA,SCC1 )
Gene Full Name: protein tyrosine phosphatase, receptor type, J
Band: 11p11.2
Quick LinksEntrez ID:5795; OMIM: 600925; Uniprot ID:PTPRJ_HUMAN; ENSEMBL ID: ENSG00000149177; HGNC ID: 9673
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus15 / 56401226
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult62 / 193912131
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor8 / 11936967
germ cell tumor2 / 2638457
glioma2 / 10688318
head and neck tumor1 / 1363027
kidney tumor2 / 6895929
leukemia19 / 95842198
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal80 / 336030723
ovarian tumor0 / 766820 
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer2 / 10268019
retinoblastoma1 / 4635621
skin tumor7 / 12494956
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood8 / 12347864
bone5 / 7165569
bone marrow0 / 488010 
brain19 / 110098917
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye7 / 21105433
heart3 / 8962633
intestine6 / 23447225
kidney18 / 21177784
larynx0 / 241450 
liver5 / 20774324
lung4 / 33697411
lymph0 / 442700 
lymph node1 / 9161010
mammary gland4 / 15327126
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas10 / 21481246
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta9 / 28082532
prostate4 / 18934521
salivary gland0 / 201550 
skin8 / 21057437
spleen0 / 539520 
stomach7 / 9661972
testis2 / 3304426
thymus0 / 811310 
thyroid2 / 4747342
tonsil1 / 1699958
trachea1 / 5241319
umbilical cord0 / 136800 
uterus6 / 23287825
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210173_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.4
Adipocyte6.6
AdrenalCortex8.1
Adrenalgland5.8
Amygdala6.9
Appendix7.7
AtrioventricularNode7.55
BDCA4+_DentriticCells6.85
Bonemarrow7.35
BronchialEpithelialCells6.55
CD105+_Endothelial6.65
CD14+_Monocytes7.15
CD19+_BCells(neg._sel.)6.8
CD33+_Myeloid8.75
CD34+8.4
CD4+_Tcells6.85
CD56+_NKCells8
CD71+_EarlyErythroid6.45
CD8+_Tcells6.2
CardiacMyocytes11.15
Caudatenucleus6.05
Cerebellum5.45
CerebellumPeduncles8.05
CiliaryGanglion5.9
CingulateCortex7.1
Colorectaladenocarcinoma6.75
DorsalRootGanglion6
FetalThyroid6.75
Fetalbrain6.5
Fetalliver5.8
Fetallung5
GlobusPallidus5.4
Heart10.7
Hypothalamus6.95
Kidney6.1
Leukemia_chronicMyelogenousK-5626.1
Leukemia_promyelocytic-HL-605.95
Leukemialymphoblastic(MOLT-4)5.1
Liver9.3
Lung7.3
Lymphnode5.5
Lymphoma_burkitts(Daudi)8.8
Lymphoma_burkitts(Raji)10.1
MedullaOblongata6.15
OccipitalLobe6.05
OlfactoryBulb5.35
Ovary4.75
Pancreas5.7
PancreaticIslet7.25
ParietalLobe7.25
Pituitary7.9
Placenta6.65
Pons6.65
PrefrontalCortex7.95
Prostate7.7
Salivarygland5.7
SkeletalMuscle8.75
Skin6.1
SmoothMuscle7.55
Spinalcord7.1
SubthalamicNucleus6.4
SuperiorCervicalGanglion10
TemporalLobe6.4
Testis5.75
TestisGermCell5.45
TestisIntersitial5.75
TestisLeydigCell7
TestisSeminiferousTubule5.85
Thalamus6.95
Thymus5.1
Thyroid7.95
Tongue7.3
Tonsil6.75
Trachea5.6
TrigeminalGanglion8.3
Uterus5.3
UterusCorpus6.45
WholeBlood8.5
Wholebrain5.3
colon6.8
pineal_day8.1
pineal_night8.02
retina8.075
small_intestine6.4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P921321
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.63 ± 0.26
Basal Forebrain7.36 ± 0.23
Basal Part of Pons7.13 ± 0.22
Cerebellar Cortex7.23 ± 0.29
Cerebellar Nuclei7.35 ± 0.27
Claustrum7.44 ± 0.51
Epithalamus7.1 ± 0.4
Frontal Lobe7.56 ± 0.36
Globus Pallidus7.58 ± 0.43
Hypothalamus7.5 ± 0.45
Insula7.81 ± 0.24
Limbic Lobe7.66 ± 0.36
Mesencephalon7.41 ± 0.4
Myelencephalon7.53 ± 0.37
Occipital Lobe7.61 ± 0.41
Parietal Lobe7.68 ± 0.33
Pontine Tegmentum7.77 ± 0.44
Striatum7.31 ± 0.5
Subthalamus7.34 ± 0.25
Temporal Lobe7.81 ± 0.31
Thalamus7.91 ± 0.42
White Matter7.3 ± 0.15
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
PtprjCBCerebellum9.45
9.35
PtprjCTXCerebral cortex95.23
92.02
PtprjHIPHippocampal region80.58
100
PtprjHPFHippocampal formation75.6
86.64
PtprjHYHypothalamus5.05
4.81
PtprjLSXLateral septal complex17.14
14.99
PtprjMBMidbrain7.43
7.53
PtprjMYMedulla1.64
1.74
PtprjOLFOlfactory bulb59.74
72.03
PtprjPPons4.01
3.7
PtprjPALPallidum10.8
9.76
PtprjRHPRetrohippocampal region57.91
59.5
PtprjsAMYStriatum-like amygdalar nuclei15.61
13.14
PtprjSTRStriatum28.41
22.97
PtprjSTRdStriatum dorsal region29.08
22.87
PtprjSTRvStriatum ventral region36.49
29.57
PtprjTHThalamus70
78.43
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00028435 12 203 214 VITEPIPVSDLR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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