AutismKB 2.0

Annotation Detail for PTPRR


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Basic Information Top
Gene Symbol:PTPRR ( DKFZp781C1038,EC-PTP,FLJ34328,MGC131968,MGC148170,PCPTP1,PTP-SL,PTPBR7,PTPRQ )
Gene Full Name: protein tyrosine phosphatase, receptor type, R
Band: 12q15
Quick LinksEntrez ID:5801; OMIM: 602853; Uniprot ID:PTPRR_HUMAN; ENSEMBL ID: ENSG00000153233; HGNC ID: 9680
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus6 / 56401210
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult26 / 193912113
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor11 / 26384541
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal65 / 336030719
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder3 / 29757100
blood0 / 1234780 
bone2 / 7165527
bone marrow0 / 488010 
brain49 / 110098944
cervix8 / 48171166
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye3 / 21105414
heart0 / 896260 
intestine1 / 2344724
kidney1 / 2117774
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle1 / 1077159
nerve3 / 15768190
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach1 / 9661910
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210675_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.05
Adipocyte6.1
AdrenalCortex7.25
Adrenalgland5.6
Amygdala13.4
Appendix7.45
AtrioventricularNode6.05
BDCA4+_DentriticCells6.2
Bonemarrow6.7
BronchialEpithelialCells5.9
CD105+_Endothelial6.1
CD14+_Monocytes6.6
CD19+_BCells(neg._sel.)6.35
CD33+_Myeloid7.6
CD34+7.4
CD4+_Tcells6.4
CD56+_NKCells6.9
CD71+_EarlyErythroid6
CD8+_Tcells5.55
CardiacMyocytes9.65
Caudatenucleus6.3
Cerebellum8.8
CerebellumPeduncles8.25
CiliaryGanglion5.2
CingulateCortex7.8
Colorectaladenocarcinoma6.2
DorsalRootGanglion5.45
FetalThyroid6.1
Fetalbrain6.7
Fetalliver5.55
Fetallung4.8
GlobusPallidus6.65
Heart9.1
Hypothalamus6.5
Kidney5.45
Leukemia_chronicMyelogenousK-5625.65
Leukemia_promyelocytic-HL-605.45
Leukemialymphoblastic(MOLT-4)4.95
Liver9
Lung6.7
Lymphnode5.15
Lymphoma_burkitts(Daudi)8.15
Lymphoma_burkitts(Raji)10.2
MedullaOblongata5.7
OccipitalLobe6.85
OlfactoryBulb4.95
Ovary4.45
Pancreas5.25
PancreaticIslet6.9
ParietalLobe7.25
Pituitary7.35
Placenta6.25
Pons6.35
PrefrontalCortex8.35
Prostate7.1
Salivarygland5.2
SkeletalMuscle8.4
Skin6.55
SmoothMuscle7
Spinalcord6.6
SubthalamicNucleus8.85
SuperiorCervicalGanglion15.2
TemporalLobe5.9
Testis5.35
TestisGermCell5.05
TestisIntersitial5.35
TestisLeydigCell6.4
TestisSeminiferousTubule5.3
Thalamus6.55
Thymus4.7
Thyroid7.5
Tongue6.6
Tonsil6.15
Trachea5.15
TrigeminalGanglion9
Uterus5.05
UterusCorpus6.2
WholeBlood6.75
Wholebrain8.7
colon6.2
pineal_day84.62
pineal_night65.88
retina7.5
small_intestine5.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7792_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.15 ± 0.58
Basal Forebrain5.55 ± 0.38
Basal Part of Pons4.96 ± 0.65
Cerebellar Cortex6.28 ± 0.23
Cerebellar Nuclei4.61 ± 0.42
Claustrum5.33 ± 0.92
Epithalamus4.96 ± 0.89
Frontal Lobe5.66 ± 0.62
Globus Pallidus4.17 ± 0.53
Hypothalamus5.58 ± 0.39
Insula6 ± 0.37
Limbic Lobe5.63 ± 0.68
Mesencephalon5.53 ± 0.66
Myelencephalon5.59 ± 0.71
Occipital Lobe5.07 ± 0.56
Parietal Lobe5.45 ± 0.49
Pontine Tegmentum5.72 ± 0.68
Striatum4.95 ± 0.56
Subthalamus5.08 ± 0.61
Temporal Lobe5.96 ± 0.44
Thalamus5.78 ± 0.5
White Matter3.89 ± 0.2
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
PtprrCBCerebellum22.05
81.34
PtprrCTXCerebral cortex3.82
2.87
PtprrHIPHippocampal region5.4
6.24
PtprrHPFHippocampal formation6.26
6.15
PtprrHYHypothalamus0.92
0.77
PtprrLSXLateral septal complex6.63
4.25
PtprrMBMidbrain0.74
0.65
PtprrMYMedulla4.95
5.86
PtprrOLFOlfactory bulb6.46
5.89
PtprrPPons1.69
2
PtprrPALPallidum2.24
2.19
PtprrRHPRetrohippocampal region7.41
5.77
PtprrsAMYStriatum-like amygdalar nuclei6.5
5.47
PtprrSTRStriatum2.21
1.78
PtprrSTRdStriatum dorsal region1.19
1.07
PtprrSTRvStriatum ventral region2.31
1.68
PtprrTHThalamus4.21
5.25
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018