AutismKB 2.0

Annotation Detail for BAX


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Basic Information Top
Gene Symbol:BAX ( BCL2L4 )
Gene Full Name: BCL2-associated X protein
Band: 19q13.33
Quick LinksEntrez ID:581; OMIM: 600040; Uniprot ID:BAX_HUMAN; ENSEMBL ID: ENSG00000087088; HGNC ID: 959
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst0 / 623190 
fetus3 / 5640125
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult62 / 193912131
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor2 / 2638457
glioma1 / 1068839
head and neck tumor42 / 136302308
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor2 / 9635920
lung tumor6 / 10312758
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal44 / 336030713
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma1 / 4635621
skin tumor1 / 1249498
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone1 / 7165513
bone marrow1 / 4880120
brain5 / 11009894
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue10 / 21572246
esophagus0 / 202090 
eye5 / 21105423
heart0 / 896260 
intestine4 / 23447217
kidney0 / 2117770 
larynx0 / 241450 
liver2 / 2077439
lung8 / 33697423
lymph1 / 4427022
lymph node0 / 916100 
mammary gland1 / 1532716
mouth4 / 6705259
muscle0 / 1077150 
nerve1 / 1576863
ovary0 / 1020510 
pancreas4 / 21481218
parathyroid1 / 2053948
pharynx37 / 41328895
pituitary gland0 / 165850 
placenta6 / 28082521
prostate1 / 1893455
salivary gland1 / 2015549
skin2 / 2105749
spleen0 / 539520 
stomach2 / 9661920
testis2 / 3304426
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 211833_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts62.05
Adipocyte6.2
AdrenalCortex6.85
Adrenalgland5.25
Amygdala6.3
Appendix6.45
AtrioventricularNode5.1
BDCA4+_DentriticCells40.35
Bonemarrow6.35
BronchialEpithelialCells6.1
CD105+_Endothelial9.6
CD14+_Monocytes35.65
CD19+_BCells(neg._sel.)71.55
CD33+_Myeloid18.8
CD34+30.35
CD4+_Tcells17.6
CD56+_NKCells49.3
CD71+_EarlyErythroid9.05
CD8+_Tcells10.95
CardiacMyocytes8.7
Caudatenucleus5.55
Cerebellum4.9
CerebellumPeduncles7.05
CiliaryGanglion4.75
CingulateCortex6.35
Colorectaladenocarcinoma12.9
DorsalRootGanglion4.9
FetalThyroid6.05
Fetalbrain6.15
Fetalliver5.4
Fetallung5.8
GlobusPallidus4.65
Heart20.05
Hypothalamus6.45
Kidney5.2
Leukemia_chronicMyelogenousK-5625.7
Leukemia_promyelocytic-HL-608.6
Leukemialymphoblastic(MOLT-4)5.2
Liver8.4
Lung17.65
Lymphnode5.3
Lymphoma_burkitts(Daudi)9.7
Lymphoma_burkitts(Raji)9
MedullaOblongata5.45
OccipitalLobe5.45
OlfactoryBulb4.85
Ovary4.2
Pancreas5.05
PancreaticIslet6.55
ParietalLobe6.6
Pituitary7.2
Placenta6.4
Pons5.7
PrefrontalCortex7.1
Prostate9.75
Salivarygland4.75
SkeletalMuscle7.65
Skin5
SmoothMuscle12.7
Spinalcord6.65
SubthalamicNucleus5.6
SuperiorCervicalGanglion7.4
TemporalLobe5.45
Testis5.2
TestisGermCell4.85
TestisIntersitial5.1
TestisLeydigCell6.1
TestisSeminiferousTubule5.3
Thalamus6.35
Thymus8.45
Thyroid7.6
Tongue6.25
Tonsil6.05
Trachea5.2
TrigeminalGanglion6.5
Uterus4.95
UterusCorpus5.75
WholeBlood29.95
Wholebrain5.05
colon12.75
pineal_day7.68
pineal_night7.58
retina7.55
small_intestine6.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P208706
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.35 ± 0.42
Basal Forebrain7.28 ± 0.31
Basal Part of Pons7.6 ± 0.28
Cerebellar Cortex7.6 ± 0.43
Cerebellar Nuclei7.52 ± 0.36
Claustrum7.2 ± 0.45
Epithalamus7.05 ± 0.46
Frontal Lobe7.44 ± 0.38
Globus Pallidus7.49 ± 0.12
Hypothalamus7.2 ± 0.36
Insula7.55 ± 0.27
Limbic Lobe7.34 ± 0.41
Mesencephalon7.26 ± 0.47
Myelencephalon7.38 ± 0.36
Occipital Lobe7.14 ± 0.37
Parietal Lobe7.42 ± 0.35
Pontine Tegmentum7.4 ± 0.36
Striatum7.18 ± 0.34
Subthalamus7.55 ± 0.14
Temporal Lobe7.56 ± 0.34
Thalamus7.34 ± 0.38
White Matter7.51 ± 0.27
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
BAX_HUMAN_21 13 21 33 TGALLLQGFIQDR PRIDE
BAX_HUMAN_65 13 65 77 IGDELDSNMELQR PRIDE
BAX_HUMAN_78 11 78 88 MIAAVDTDSPR PRIDE
PAp00131190 20 38 57 MGGEAPELALDPVPQDASTK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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