AutismKB 2.0

Annotation Detail for NGB


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Basic Information Top
Gene Symbol:NGB ( - )
Gene Full Name: neuroglobin
Band: 14q24.3
Quick LinksEntrez ID:58157; OMIM: 605304; Uniprot ID:NGB_HUMAN; ENSEMBL ID: ENSG00000165553; HGNC ID: 14077
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus2 / 5640123
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult4 / 19391212
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal20 / 33603075
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain9 / 11009898
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye4 / 21105418
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220337_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.45
Adipocyte5.15
AdrenalCortex5.9
Adrenalgland4.35
Amygdala5.4
Appendix5.4
AtrioventricularNode4.3
BDCA4+_DentriticCells5.3
Bonemarrow5.25
BronchialEpithelialCells5.05
CD105+_Endothelial5.25
CD14+_Monocytes5.5
CD19+_BCells(neg._sel.)5.4
CD33+_Myeloid6.65
CD34+6.35
CD4+_Tcells5.65
CD56+_NKCells6.05
CD71+_EarlyErythroid9.5
CD8+_Tcells5.05
CardiacMyocytes6.5
Caudatenucleus4.65
Cerebellum4.2
CerebellumPeduncles5.95
CiliaryGanglion3.85
CingulateCortex5.4
Colorectaladenocarcinoma5.15
DorsalRootGanglion4
FetalThyroid5
Fetalbrain5.15
Fetalliver4.6
Fetallung4.3
GlobusPallidus4.15
Heart7.2
Hypothalamus5.65
Kidney4.4
Leukemia_chronicMyelogenousK-5624.7
Leukemia_promyelocytic-HL-604.6
Leukemialymphoblastic(MOLT-4)4.1
Liver6.9
Lung5.75
Lymphnode4.4
Lymphoma_burkitts(Daudi)6.7
Lymphoma_burkitts(Raji)7.45
MedullaOblongata4.75
OccipitalLobe4.65
OlfactoryBulb4.1
Ovary3.55
Pancreas4.15
PancreaticIslet5.55
ParietalLobe5.55
Pituitary6.1
Placenta5.3
Pons4.95
PrefrontalCortex6.5
Prostate6.05
Salivarygland4.6
SkeletalMuscle6.5
Skin4.25
SmoothMuscle5.8
Spinalcord5.55
SubthalamicNucleus4.85
SuperiorCervicalGanglion7.35
TemporalLobe5
Testis4.5
TestisGermCell4.25
TestisIntersitial4.3
TestisLeydigCell5.2
TestisSeminiferousTubule4.4
Thalamus5.35
Thymus4.05
Thyroid6.45
Tongue5.2
Tonsil5.1
Trachea4.35
TrigeminalGanglion5.65
Uterus4.2
UterusCorpus4.65
WholeBlood5.6
Wholebrain4.45
colon5.15
pineal_day6.46
pineal_night6.32
retina6.3
small_intestine5.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_11196_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.05 ± 0.97
Basal Forebrain3.21 ± 0.52
Basal Part of Pons2.2 ± 0.3
Cerebellar Cortex2.64 ± 0.7
Cerebellar Nuclei2.97 ± 0.73
Claustrum2.89 ± 0.76
Epithalamus3.2 ± 1.14
Frontal Lobe3.34 ± 0.82
Globus Pallidus1.91 ± 0.81
Hypothalamus4.18 ± 1.04
Insula3.56 ± 0.64
Limbic Lobe2.55 ± 0.83
Mesencephalon3.26 ± 0.95
Myelencephalon3.06 ± 0.91
Occipital Lobe2.3 ± 0.81
Parietal Lobe3.14 ± 0.81
Pontine Tegmentum3.05 ± 0.81
Striatum2.28 ± 0.94
Subthalamus2.81 ± 0.76
Temporal Lobe3.28 ± 0.7
Thalamus2.99 ± 0.73
White Matter1.8 ± 0.22
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
NgbCBCerebellum4.91
4.83
NgbCTXCerebral cortex1.27
1
NgbHIPHippocampal region1.22
0.91
NgbHPFHippocampal formation1.94
1.57
NgbHYHypothalamus20.57
16.37
NgbLSXLateral septal complex2.53
2.66
NgbMBMidbrain3.18
2.87
NgbMYMedulla9.44
8.63
NgbOLFOlfactory bulb3.43
2.13
NgbPPons5.1
5.85
NgbPALPallidum2.85
2.49
NgbRHPRetrohippocampal region3.28
2.55
NgbsAMYStriatum-like amygdalar nuclei13.75
10.78
NgbSTRStriatum1.65
1.35
NgbSTRdStriatum dorsal region0.23
0.21
NgbSTRvStriatum ventral region0.71
0.41
NgbTHThalamus1.5
1.23
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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