AutismKB 2.0

Annotation Detail for SQRDL


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Basic Information Top
Gene Symbol:SQRDL ( - )
Gene Full Name: sulfide quinone reductase-like (yeast)
Band: 15q15
Quick LinksEntrez ID:58472; OMIM: NA; Uniprot ID:SQRD_HUMAN; ENSEMBL ID: ENSG00000137767; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus30 / 56401253
neonate2 / 3109764
infant0 / 236200 
juvenile0 / 555560 
adult198 / 1939121102
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor6 / 9417863
cervical tumor5 / 34366145
chondrosarcoma12 / 82823144
colorectal tumor10 / 11424687
esophageal tumor2 / 17290115
gastrointestinal tumor7 / 11936958
germ cell tumor2 / 2638457
glioma5 / 10688346
head and neck tumor2 / 13630214
kidney tumor5 / 6895972
leukemia19 / 95842198
liver tumor18 / 96359186
lung tumor10 / 10312796
lymphoma3 / 7175541
non-neoplasia8 / 9725082
normal273 / 336030781
ovarian tumor0 / 766820 
pancreatic tumor17 / 104616162
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor5 / 12494940
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland0 / 331970 
ascites4 / 4001599
bladder1 / 2975733
blood32 / 123478259
bone6 / 7165583
bone marrow3 / 4880161
brain24 / 110098921
cervix7 / 48171145
connective tissue14 / 14925593
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus5 / 20209247
eye7 / 21105433
heart7 / 8962678
intestine63 / 234472268
kidney17 / 21177780
larynx1 / 2414541
liver33 / 207743158
lung48 / 336974142
lymph0 / 442700 
lymph node4 / 9161043
mammary gland30 / 153271195
mouth0 / 670520 
muscle7 / 10771564
nerve1 / 1576863
ovary2 / 10205119
pancreas33 / 214812153
parathyroid2 / 2053997
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta15 / 28082553
prostate15 / 18934579
salivary gland1 / 2015549
skin7 / 21057433
spleen2 / 5395237
stomach9 / 9661993
testis1 / 3304423
thymus4 / 8113149
thyroid2 / 4747342
tonsil1 / 1699958
trachea1 / 5241319
umbilical cord0 / 136800 
uterus13 / 23287855
vascular5 / 5178096
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 217995_at
Cell line Expression level Expression bar
721_B_lymphoblasts289.45
Adipocyte46.95
AdrenalCortex13.4
Adrenalgland14.05
Amygdala13
Appendix16.65
AtrioventricularNode10.85
BDCA4+_DentriticCells228.85
Bonemarrow55.6
BronchialEpithelialCells931.2
CD105+_Endothelial317.8
CD14+_Monocytes1189.55
CD19+_BCells(neg._sel.)136.85
CD33+_Myeloid969.15
CD34+22.8
CD4+_Tcells40
CD56+_NKCells93.6
CD71+_EarlyErythroid147
CD8+_Tcells84.35
CardiacMyocytes26
Caudatenucleus9.45
Cerebellum9.65
CerebellumPeduncles8.85
CiliaryGanglion12.45
CingulateCortex12.3
Colorectaladenocarcinoma10.7
DorsalRootGanglion13.95
FetalThyroid19
Fetalbrain10.8
Fetalliver14.4
Fetallung60
GlobusPallidus9.65
Heart21.9
Hypothalamus13.1
Kidney15.7
Leukemia_chronicMyelogenousK-56210.8
Leukemia_promyelocytic-HL-6011
Leukemialymphoblastic(MOLT-4)14.75
Liver40.15
Lung443.9
Lymphnode38.4
Lymphoma_burkitts(Daudi)79.15
Lymphoma_burkitts(Raji)19.3
MedullaOblongata10.7
OccipitalLobe8.05
OlfactoryBulb19.4
Ovary11
Pancreas20.15
PancreaticIslet31.15
ParietalLobe9.7
Pituitary19.65
Placenta17.35
Pons11.65
PrefrontalCortex13.55
Prostate69.8
Salivarygland21.2
SkeletalMuscle17.45
Skin16.5
SmoothMuscle143.4
Spinalcord15.9
SubthalamicNucleus8.65
SuperiorCervicalGanglion16.35
TemporalLobe10.95
Testis14.6
TestisGermCell10.85
TestisIntersitial11.65
TestisLeydigCell12
TestisSeminiferousTubule11
Thalamus10.5
Thymus47.05
Thyroid61.8
Tongue48.1
Tonsil43
Trachea48.85
TrigeminalGanglion14.1
Uterus14.05
UterusCorpus18.85
WholeBlood485.9
Wholebrain8.95
colon1396.8
pineal_day14.3
pineal_night12.9
retina29.625
small_intestine144.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8219_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.34 ± 0.69
Basal Forebrain4.42 ± 0.26
Basal Part of Pons4.26 ± 0.59
Cerebellar Cortex4.13 ± 0.32
Cerebellar Nuclei5 ± 0.57
Claustrum3.82 ± 0.79
Epithalamus4.97 ± 0.45
Frontal Lobe4.79 ± 0.38
Globus Pallidus5.67 ± 0.38
Hypothalamus4.44 ± 0.66
Insula4.6 ± 0.3
Limbic Lobe4.47 ± 0.63
Mesencephalon4.84 ± 0.53
Myelencephalon4.68 ± 0.61
Occipital Lobe4.39 ± 0.57
Parietal Lobe4.5 ± 0.6
Pontine Tegmentum4.78 ± 0.58
Striatum5.35 ± 0.43
Subthalamus4.92 ± 0.67
Temporal Lobe4.65 ± 0.61
Thalamus4.82 ± 0.52
White Matter4.01 ± 0.82
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
SqrdlCBCerebellum19.49
21.8
SqrdlCTXCerebral cortex38.7
25.41
SqrdlHIPHippocampal region25.54
27.45
SqrdlHPFHippocampal formation26.46
23.74
SqrdlHYHypothalamus12.4
9.05
SqrdlLSXLateral septal complex11.15
8.9
SqrdlMBMidbrain19.27
15.52
SqrdlMYMedulla33.55
31.78
SqrdlOLFOlfactory bulb37.87
30.13
SqrdlPPons22.84
19.74
SqrdlPALPallidum19.14
14.64
SqrdlRHPRetrohippocampal region26.75
18.52
SqrdlsAMYStriatum-like amygdalar nuclei13.97
8.95
SqrdlSTRStriatum6.9
4.94
SqrdlSTRdStriatum dorsal region4.33
3.32
SqrdlSTRvStriatum ventral region9.02
5.8
SqrdlTHThalamus8.95
6.72
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00003314 15 80 94 HFYQPIWTLVGAGAK Peptide Atlas
SQRD_HUMAN_0 0 0 0 ADLMPFLYWNMMLR PRIDE
SQRD_HUMAN_0 0 0 0 EGNAIFTFPNTPVK PRIDE
SQRD_HUMAN_0 0 0 0 IMYLSEAYFR PRIDE
SQRD_HUMAN_0 0 0 0 KVGAENVAIVEPSER PRIDE
SQRD_HUMAN_0 0 0 0 TAAAVAAQSGILDR PRIDE
SQRD_HUMAN_0 0 0 0 VGAENVAIVEPSER PRIDE
SQRD_HUMAN_0 0 0 0 VILAEFDYK PRIDE
SQRD_HUMAN_117 22 117 138 VTELNPDKNCIHTDDDEKISYR PRIDE
SQRD_HUMAN_186 14 186 199 EGNAIFTFPNTPVK PRIDE
SQRD_HUMAN_207 10 207 216 IMYLSEAYFR PRIDE
SQRD_HUMAN_241 12 241 252 YADALQEIIQER PRIDE
SQRD_HUMAN_305 21 305 325 TSPVADAAGWVDVDKETLQHR PRIDE
SQRD_HUMAN_344 14 344 357 TAAAVAAQSGILDR PRIDE
SQRD_HUMAN_345 14 345 358 TAAAVAAQSGILDR PRIDE
SQRD_HUMAN_387 24 387 410 VILAEFDYKAEPLETFPFDQSKER PRIDE
SQRD_HUMAN_418 14 418 431 ADLMPFLYWNMMLR PRIDE
SQRD_HUMAN_64 15 64 78 KVGAENVAIVEPSER PRIDE
SQRD_HUMAN_65 14 65 78 VGAENVAIVEPSER PRIDE
SQRD_HUMAN_79 15 79 93 HFYQPIWTLVGAGAK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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