AutismKB 2.0

Annotation Detail for OVOL2


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Basic Information Top
Gene Symbol:OVOL2 ( EUROIMAGE566589,ZNF339 )
Gene Full Name: ovo-like 2 (Drosophila)
Band: 20p11.23
Quick LinksEntrez ID:58495; OMIM: NA; Uniprot ID:OVOL2_HUMAN; ENSEMBL ID: ENSG00000125850; HGNC ID: 15804
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult4 / 19391212
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult8 / 19391214
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal0 / 33603070 
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor3 / 26384511
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor4 / 10312738
lymphoma5 / 7175569
non-neoplasia1 / 9725010
normal10 / 33603072
ovarian tumor2 / 7668226
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine4 / 23447217
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain2 / 11009891
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine6 / 23447225
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung6 / 33697417
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary2 / 10205119
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate1 / 1893455
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach1 / 9661910
testis5 / 33044215
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 211778_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.15
Adipocyte4.35
AdrenalCortex4.55
Adrenalgland3.55
Amygdala4.65
Appendix4.45
AtrioventricularNode12.05
BDCA4+_DentriticCells4.4
Bonemarrow4.35
BronchialEpithelialCells5.4
CD105+_Endothelial4.4
CD14+_Monocytes4.35
CD19+_BCells(neg._sel.)4.35
CD33+_Myeloid5.5
CD34+5.2
CD4+_Tcells4.45
CD56+_NKCells5.05
CD71+_EarlyErythroid4.1
CD8+_Tcells3.9
CardiacMyocytes5.55
Caudatenucleus3.95
Cerebellum3.55
CerebellumPeduncles4.9
CiliaryGanglion6.25
CingulateCortex4.55
Colorectaladenocarcinoma6.1
DorsalRootGanglion4.15
FetalThyroid7.4
Fetalbrain4.45
Fetalliver3.8
Fetallung4
GlobusPallidus3.4
Heart5.6
Hypothalamus4.8
Kidney3.55
Leukemia_chronicMyelogenousK-5623.8
Leukemia_promyelocytic-HL-603.75
Leukemialymphoblastic(MOLT-4)3.55
Liver5.75
Lung23.05
Lymphnode3.8
Lymphoma_burkitts(Daudi)5.6
Lymphoma_burkitts(Raji)6.25
MedullaOblongata4.1
OccipitalLobe3.75
OlfactoryBulb3.5
Ovary2.9
Pancreas3.5
PancreaticIslet5.4
ParietalLobe4.65
Pituitary5.15
Placenta4.55
Pons4.15
PrefrontalCortex5.75
Prostate8.5
Salivarygland3.75
SkeletalMuscle5.6
Skin7.55
SmoothMuscle5.1
Spinalcord4.65
SubthalamicNucleus4.4
SuperiorCervicalGanglion8.85
TemporalLobe4.05
Testis33.85
TestisGermCell6.05
TestisIntersitial5.55
TestisLeydigCell5.4
TestisSeminiferousTubule9.75
Thalamus4.4
Thymus3.3
Thyroid8.5
Tongue5.3
Tonsil4.2
Trachea6.2
TrigeminalGanglion8
Uterus3.65
UterusCorpus4.95
WholeBlood4.5
Wholebrain3.65
colon6.3
pineal_day5.3
pineal_night5.2
retina5.45
small_intestine4.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P143348
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.14 ± 0.81
Basal Forebrain3.35 ± 0.25
Basal Part of Pons3.46 ± 0.54
Cerebellar Cortex3.17 ± 0.5
Cerebellar Nuclei3.66 ± 0.65
Claustrum4.78 ± 0.76
Epithalamus3.13 ± 0.85
Frontal Lobe4.34 ± 0.59
Globus Pallidus2.5 ± 1.02
Hypothalamus3.53 ± 0.67
Insula4.4 ± 0.37
Limbic Lobe4.05 ± 0.82
Mesencephalon3.95 ± 0.87
Myelencephalon3.75 ± 0.81
Occipital Lobe3.02 ± 0.64
Parietal Lobe4.05 ± 0.72
Pontine Tegmentum3.93 ± 0.86
Striatum2.63 ± 1.33
Subthalamus3.66 ± 0.79
Temporal Lobe3.94 ± 0.59
Thalamus3.4 ± 0.69
White Matter2.07 ± 0.97
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018