AutismKB 2.0

Annotation Detail for ZNF462


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Basic Information Top
Gene Symbol:ZNF462 ( DKFZp686B2325,DKFZp762N2316,FLJ14960,FLJ45904,KIAA1803,Zfp462 )
Gene Full Name: zinc finger protein 462
Band: 9q31.2
Quick LinksEntrez ID:58499; OMIM: NA; Uniprot ID:ZN462_HUMAN; ENSEMBL ID: ENSG00000148143; HGNC ID: 21684
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst3 / 6231948
fetus20 / 56401235
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult70 / 193912136
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor1 / 3436629
chondrosarcoma0 / 828230 
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor4 / 26384515
glioma2 / 10688318
head and neck tumor5 / 13630236
kidney tumor2 / 6895929
leukemia1 / 9584210
liver tumor4 / 9635941
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal98 / 336030729
ovarian tumor1 / 7668213
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor9 / 12494972
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites1 / 4001524
bladder0 / 297570 
blood1 / 1234788
bone2 / 7165527
bone marrow0 / 488010 
brain16 / 110098914
cervix1 / 4817120
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye9 / 21105442
heart1 / 8962611
intestine6 / 23447225
kidney4 / 21177718
larynx2 / 2414582
liver5 / 20774324
lung4 / 33697411
lymph0 / 442700 
lymph node0 / 916100 
mammary gland9 / 15327158
mouth1 / 6705214
muscle2 / 10771518
nerve0 / 157680 
ovary1 / 1020519
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta5 / 28082517
prostate17 / 18934589
salivary gland0 / 201550 
skin12 / 21057456
spleen0 / 539520 
stomach0 / 966190 
testis18 / 33044254
thymus1 / 8113112
thyroid2 / 4747342
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_13438_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.32 ± 0.33
Basal Forebrain7.89 ± 0.18
Basal Part of Pons6.98 ± 0.38
Cerebellar Cortex7.38 ± 0.22
Cerebellar Nuclei7.4 ± 0.3
Claustrum7.56 ± 0.56
Epithalamus7.52 ± 0.25
Frontal Lobe7.17 ± 0.39
Globus Pallidus8.4 ± 0.27
Hypothalamus7.47 ± 0.27
Insula7.2 ± 0.27
Limbic Lobe7.34 ± 0.59
Mesencephalon7.61 ± 0.39
Myelencephalon7.51 ± 0.4
Occipital Lobe7.69 ± 0.45
Parietal Lobe7.26 ± 0.47
Pontine Tegmentum7.55 ± 0.42
Striatum8.12 ± 0.48
Subthalamus7.31 ± 0.25
Temporal Lobe7.33 ± 0.34
Thalamus7.76 ± 0.24
White Matter8.92 ± 0.54
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Zfp462CBCerebellum20.67
34.48
Zfp462CTXCerebral cortex21.74
16.3
Zfp462HIPHippocampal region26.8
40.2
Zfp462HPFHippocampal formation23.17
28.79
Zfp462HYHypothalamus20.77
15.88
Zfp462LSXLateral septal complex33.24
24.93
Zfp462MBMidbrain25.61
22.43
Zfp462MYMedulla16.55
17.27
Zfp462OLFOlfactory bulb49.25
44.02
Zfp462PPons13.37
12.72
Zfp462PALPallidum20.89
18.63
Zfp462RHPRetrohippocampal region18.68
16.69
Zfp462sAMYStriatum-like amygdalar nuclei31.4
22.91
Zfp462STRStriatum38.03
28.32
Zfp462STRdStriatum dorsal region36.53
27.16
Zfp462STRvStriatum ventral region47.3
35.57
Zfp462THThalamus30.99
27.55
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018