AutismKB 2.0

Annotation Detail for ZNF250


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Basic Information Top
Gene Symbol:ZNF250 ( FLJ57354,MGC111123,MGC9718,ZFP647,ZNF647 )
Gene Full Name: zinc finger protein 250
Band: 8q24.3
Quick LinksEntrez ID:58500; OMIM: NA; Uniprot ID:ZN250_HUMAN; ENSEMBL ID: ENSG00000196150; HGNC ID: 13044
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus18 / 56401231
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult23 / 193912111
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor1 / 2638453
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal63 / 336030718
ovarian tumor4 / 7668252
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone2 / 7165527
bone marrow0 / 488010 
brain22 / 110098919
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye4 / 21105418
heart4 / 8962644
intestine3 / 23447212
kidney3 / 21177714
larynx0 / 241450 
liver1 / 2077434
lung6 / 33697417
lymph0 / 442700 
lymph node1 / 9161010
mammary gland0 / 1532710 
mouth1 / 6705214
muscle1 / 1077159
nerve0 / 157680 
ovary4 / 10205139
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta1 / 2808253
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen3 / 5395255
stomach1 / 9661910
testis4 / 33044212
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus3 / 23287812
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213858_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.35
Adipocyte5.6
AdrenalCortex6.15
Adrenalgland4.95
Amygdala5.8
Appendix6.2
AtrioventricularNode5.05
BDCA4+_DentriticCells5.95
Bonemarrow5.95
BronchialEpithelialCells5.5
CD105+_Endothelial5.55
CD14+_Monocytes6.45
CD19+_BCells(neg._sel.)6.95
CD33+_Myeloid6.95
CD34+6.7
CD4+_Tcells5.8
CD56+_NKCells6.3
CD71+_EarlyErythroid5.35
CD8+_Tcells5.1
CardiacMyocytes7.15
Caudatenucleus5.05
Cerebellum4.6
CerebellumPeduncles6.45
CiliaryGanglion4.45
CingulateCortex5.75
Colorectaladenocarcinoma5.65
DorsalRootGanglion4.75
FetalThyroid6
Fetalbrain6
Fetalliver5
Fetallung4.7
GlobusPallidus4.35
Heart8.15
Hypothalamus5.85
Kidney4.95
Leukemia_chronicMyelogenousK-5625.1
Leukemia_promyelocytic-HL-605
Leukemialymphoblastic(MOLT-4)4.75
Liver8.05
Lung6.1
Lymphnode5.1
Lymphoma_burkitts(Daudi)7.4
Lymphoma_burkitts(Raji)8.4
MedullaOblongata5.15
OccipitalLobe5.05
OlfactoryBulb4.4
Ovary3.95
Pancreas4.65
PancreaticIslet6.1
ParietalLobe6.2
Pituitary6.6
Placenta5.75
Pons5.35
PrefrontalCortex6.75
Prostate6.65
Salivarygland4.65
SkeletalMuscle6.9
Skin5.8
SmoothMuscle6.3
Spinalcord5.95
SubthalamicNucleus5.3
SuperiorCervicalGanglion7.25
TemporalLobe5.15
Testis5.1
TestisGermCell4.6
TestisIntersitial4.7
TestisLeydigCell5.75
TestisSeminiferousTubule5.75
Thalamus5.8
Thymus4.4
Thyroid6.95
Tongue5.7
Tonsil5.6
Trachea4.7
TrigeminalGanglion6.25
Uterus4.55
UterusCorpus5.35
WholeBlood6.2
Wholebrain4.65
colon5.65
pineal_day6.84
pineal_night6.76
retina6.775
small_intestine5.4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P205019
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.28 ± 0.37
Basal Forebrain6.5 ± 0.17
Basal Part of Pons6.46 ± 0.17
Cerebellar Cortex6.76 ± 0.24
Cerebellar Nuclei6.47 ± 0.28
Claustrum6.01 ± 0.57
Epithalamus6.38 ± 0.41
Frontal Lobe6.23 ± 0.34
Globus Pallidus6.05 ± 0.26
Hypothalamus6.48 ± 0.52
Insula6.26 ± 0.29
Limbic Lobe6.14 ± 0.39
Mesencephalon6.26 ± 0.57
Myelencephalon6.3 ± 0.39
Occipital Lobe6.65 ± 0.29
Parietal Lobe6.45 ± 0.29
Pontine Tegmentum6.33 ± 0.26
Striatum5.81 ± 0.27
Subthalamus6.62 ± 0.2
Temporal Lobe6.25 ± 0.37
Thalamus6.34 ± 0.33
White Matter6.32 ± 0.24
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Zfp647CBCerebellum1.09
1.07
Zfp647CTXCerebral cortex4.75
1.69
Zfp647HIPHippocampal region3.19
2.35
Zfp647HPFHippocampal formation2.6
1.75
Zfp647HYHypothalamus0.88
0.38
Zfp647LSXLateral septal complex0.23
0.19
Zfp647MBMidbrain1.05
0.65
Zfp647MYMedulla1.56
0.98
Zfp647OLFOlfactory bulb3.2
1.43
Zfp647PPons1.33
0.86
Zfp647PALPallidum1.03
0.75
Zfp647RHPRetrohippocampal region1.5
0.85
Zfp647sAMYStriatum-like amygdalar nuclei1.04
0.57
Zfp647STRStriatum0.57
0.28
Zfp647STRdStriatum dorsal region0.43
0.23
Zfp647STRvStriatum ventral region0.84
0.3
Zfp647THThalamus0.71
0.46
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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