AutismKB 2.0

Annotation Detail for RABGGTA


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Basic Information Top
Gene Symbol:RABGGTA ( PTAR3 )
Gene Full Name: Rab geranylgeranyltransferase, alpha subunit
Band: 14q11.2
Quick LinksEntrez ID:5875; OMIM: 601905; Uniprot ID:PGTA_HUMAN; ENSEMBL ID: ENSG00000100949; HGNC ID: 9795
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus28 / 56401249
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult125 / 193912164
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor2 / 3436658
chondrosarcoma4 / 8282348
colorectal tumor6 / 11424652
esophageal tumor1 / 1729057
gastrointestinal tumor4 / 11936933
germ cell tumor9 / 26384534
glioma3 / 10688328
head and neck tumor14 / 136302102
kidney tumor2 / 6895929
leukemia4 / 9584241
liver tumor5 / 9635951
lung tumor6 / 10312758
lymphoma20 / 71755278
non-neoplasia2 / 9725020
normal237 / 336030770
ovarian tumor2 / 7668226
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS39 / 125680310
prostate cancer7 / 10268068
retinoblastoma5 / 46356107
skin tumor3 / 12494924
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland7 / 33197210
ascites3 / 4001574
bladder1 / 2975733
blood9 / 12347872
bone4 / 7165555
bone marrow3 / 4880161
brain80 / 110098972
cervix2 / 4817141
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus2 / 2020998
eye12 / 21105456
heart6 / 8962666
intestine14 / 23447259
kidney12 / 21177756
larynx1 / 2414541
liver7 / 20774333
lung18 / 33697453
lymph0 / 442700 
lymph node5 / 9161054
mammary gland1 / 1532716
mouth6 / 6705289
muscle2 / 10771518
nerve1 / 1576863
ovary4 / 10205139
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx5 / 41328120
pituitary gland3 / 16585180
placenta29 / 280825103
prostate15 / 18934579
salivary gland0 / 201550 
skin5 / 21057423
spleen14 / 53952259
stomach2 / 9661920
testis20 / 33044260
thymus11 / 81131135
thyroid6 / 47473126
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus7 / 23287830
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203573_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts37.25
Adipocyte7.4
AdrenalCortex7.7
Adrenalgland6.35
Amygdala8.8
Appendix7.5
AtrioventricularNode5.6
BDCA4+_DentriticCells15.75
Bonemarrow9.05
BronchialEpithelialCells38.15
CD105+_Endothelial7.7
CD14+_Monocytes30.55
CD19+_BCells(neg._sel.)19.2
CD33+_Myeloid20.25
CD34+11.05
CD4+_Tcells8.55
CD56+_NKCells52.75
CD71+_EarlyErythroid7.1
CD8+_Tcells7.75
CardiacMyocytes10.2
Caudatenucleus6.8
Cerebellum6.25
CerebellumPeduncles8.8
CiliaryGanglion5.25
CingulateCortex7.85
Colorectaladenocarcinoma7.2
DorsalRootGanglion5.75
FetalThyroid7.45
Fetalbrain7.3
Fetalliver6.55
Fetallung6.55
GlobusPallidus5.5
Heart36.45
Hypothalamus7.65
Kidney6.35
Leukemia_chronicMyelogenousK-5626.8
Leukemia_promyelocytic-HL-606.7
Leukemialymphoblastic(MOLT-4)6.15
Liver19.05
Lung13.3
Lymphnode6.55
Lymphoma_burkitts(Daudi)9.65
Lymphoma_burkitts(Raji)12.6
MedullaOblongata6.8
OccipitalLobe6.85
OlfactoryBulb5.95
Ovary4.95
Pancreas6.05
PancreaticIslet8.85
ParietalLobe7.95
Pituitary8.95
Placenta8.95
Pons7.1
PrefrontalCortex9.5
Prostate16.1
Salivarygland5.95
SkeletalMuscle7.7
Skin5.9
SmoothMuscle10.45
Spinalcord7.5
SubthalamicNucleus7.05
SuperiorCervicalGanglion8.35
TemporalLobe6.95
Testis6.6
TestisGermCell7.75
TestisIntersitial6.25
TestisLeydigCell7.5
TestisSeminiferousTubule6.4
Thalamus7.95
Thymus6.75
Thyroid10.4
Tongue7.9
Tonsil7.35
Trachea6.35
TrigeminalGanglion7.6
Uterus5.7
UterusCorpus6.65
WholeBlood11.25
Wholebrain20.25
colon7.55
pineal_day9.5
pineal_night10.32
retina9.025
small_intestine6.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7861_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.25 ± 0.56
Basal Forebrain5.52 ± 0.36
Basal Part of Pons5.05 ± 0.42
Cerebellar Cortex5.01 ± 0.52
Cerebellar Nuclei5.23 ± 0.49
Claustrum5.58 ± 0.65
Epithalamus4.4 ± 0.57
Frontal Lobe5.3 ± 0.53
Globus Pallidus5.63 ± 0.69
Hypothalamus4.97 ± 0.56
Insula5.17 ± 0.36
Limbic Lobe5.32 ± 0.55
Mesencephalon5.38 ± 0.53
Myelencephalon5.34 ± 0.59
Occipital Lobe5.3 ± 0.62
Parietal Lobe5.23 ± 0.51
Pontine Tegmentum5.29 ± 0.51
Striatum5.55 ± 0.52
Subthalamus5.4 ± 0.22
Temporal Lobe5.22 ± 0.61
Thalamus5.47 ± 0.51
White Matter5.05 ± 1.02
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
RabggtaCBCerebellum11.8
12.71
RabggtaCTXCerebral cortex43.16
32.42
RabggtaHIPHippocampal region23.63
29.33
RabggtaHPFHippocampal formation32.78
33.97
RabggtaHYHypothalamus8.15
6.09
RabggtaLSXLateral septal complex3.47
2.55
RabggtaMBMidbrain16.12
13.92
RabggtaMYMedulla19.3
19.43
RabggtaOLFOlfactory bulb22.78
16.84
RabggtaPPons13.52
12.92
RabggtaPALPallidum8.9
7.2
RabggtaRHPRetrohippocampal region50.32
42.45
RabggtasAMYStriatum-like amygdalar nuclei4.52
2.9
RabggtaSTRStriatum12.12
8.32
RabggtaSTRdStriatum dorsal region15.06
10.62
RabggtaSTRvStriatum ventral region10.47
6.42
RabggtaTHThalamus15.24
12.25
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00095313 11 91 101 AELGFLESCLR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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