AutismKB 2.0

Annotation Detail for RAC3


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Basic Information Top
Gene Symbol:RAC3 ( - )
Gene Full Name: ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
Band: 17q25.3
Quick LinksEntrez ID:5881; OMIM: 602050; Uniprot ID:RAC3_HUMAN; ENSEMBL ID: ENSG00000169750; HGNC ID: 9803
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst0 / 623190 
fetus4 / 5640127
neonate0 / 310970 
infant2 / 2362084
juvenile1 / 5555617
adult13 / 19391216
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor2 / 2638457
glioma4 / 10688337
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma1 / 7175513
non-neoplasia3 / 9725030
normal23 / 33603076
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain18 / 110098916
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye2 / 2110549
heart0 / 896260 
intestine2 / 2344728
kidney0 / 2117770 
larynx0 / 241450 
liver1 / 2077434
lung3 / 3369748
lymph1 / 4427022
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve1 / 1576863
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate1 / 1893455
salivary gland2 / 2015599
skin0 / 2105740 
spleen0 / 539520 
stomach2 / 9661920
testis3 / 3304429
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206103_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.35
Adipocyte5.65
AdrenalCortex6.55
Adrenalgland4.95
Amygdala6.65
Appendix6.15
AtrioventricularNode4.9
BDCA4+_DentriticCells6.3
Bonemarrow6
BronchialEpithelialCells6.8
CD105+_Endothelial5.6
CD14+_Monocytes6.3
CD19+_BCells(neg._sel.)6
CD33+_Myeloid7
CD34+7.3
CD4+_Tcells6.65
CD56+_NKCells6.55
CD71+_EarlyErythroid5.5
CD8+_Tcells5.25
CardiacMyocytes7.85
Caudatenucleus5.2
Cerebellum4.75
CerebellumPeduncles6.65
CiliaryGanglion4.45
CingulateCortex6
Colorectaladenocarcinoma5.95
DorsalRootGanglion4.55
FetalThyroid5.7
Fetalbrain5.65
Fetalliver5.05
Fetallung4.8
GlobusPallidus4.45
Heart7.75
Hypothalamus6.1
Kidney4.95
Leukemia_chronicMyelogenousK-5625.25
Leukemia_promyelocytic-HL-605.15
Leukemialymphoblastic(MOLT-4)4.6
Liver8.55
Lung6.75
Lymphnode4.9
Lymphoma_burkitts(Daudi)7.55
Lymphoma_burkitts(Raji)8.55
MedullaOblongata5.3
OccipitalLobe5.2
OlfactoryBulb4.6
Ovary4.05
Pancreas4.85
PancreaticIslet6.3
ParietalLobe6.25
Pituitary6.85
Placenta5.9
Pons5.6
PrefrontalCortex6.95
Prostate6.85
Salivarygland4.7
SkeletalMuscle7.7
Skin4.75
SmoothMuscle6.55
Spinalcord6.15
SubthalamicNucleus5.35
SuperiorCervicalGanglion6.7
TemporalLobe5.35
Testis5
TestisGermCell4.85
TestisIntersitial4.9
TestisLeydigCell5.9
TestisSeminiferousTubule5.15
Thalamus5.9
Thymus4.6
Thyroid7.3
Tongue5.9
Tonsil5.7
Trachea4.85
TrigeminalGanglion6.5
Uterus4.7
UterusCorpus5.55
WholeBlood6.35
Wholebrain9
colon5.9
pineal_day7.04
pineal_night6.92
retina7.025
small_intestine5.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8289_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.28 ± 0.97
Basal Forebrain2.72 ± 0.5
Basal Part of Pons2.43 ± 0.4
Cerebellar Cortex2.6 ± 0.62
Cerebellar Nuclei3.19 ± 0.67
Claustrum3.5 ± 0.85
Epithalamus2.44 ± 0.79
Frontal Lobe2.64 ± 0.73
Globus Pallidus3.23 ± 0.59
Hypothalamus2.58 ± 0.65
Insula2.44 ± 0.58
Limbic Lobe2.87 ± 0.69
Mesencephalon2.91 ± 0.72
Myelencephalon2.81 ± 0.71
Occipital Lobe3.03 ± 0.59
Parietal Lobe2.88 ± 0.79
Pontine Tegmentum2.85 ± 0.7
Striatum2.92 ± 0.92
Subthalamus2.93 ± 0.82
Temporal Lobe2.68 ± 0.8
Thalamus2.7 ± 0.68
White Matter3.19 ± 0.35
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rac3CBCerebellum0.67
0.74
Rac3CTXCerebral cortex1.11
1.23
Rac3HIPHippocampal region1.86
1.8
Rac3HPFHippocampal formation2.24
2.01
Rac3HYHypothalamus0.78
0.77
Rac3LSXLateral septal complex0.17
0.17
Rac3MBMidbrain1.47
1.48
Rac3MYMedulla1.54
1.65
Rac3OLFOlfactory bulb2.19
2.04
Rac3PPons2.67
2.97
Rac3PALPallidum0.73
0.74
Rac3RHPRetrohippocampal region2.94
2.14
Rac3sAMYStriatum-like amygdalar nuclei0.22
0.12
Rac3STRStriatum0.37
0.35
Rac3STRdStriatum dorsal region0.46
0.45
Rac3STRvStriatum ventral region0.2
0.2
Rac3THThalamus1.56
1.19
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00000774 9 175 183 AVLCPPPVK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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