AutismKB 2.0

Annotation Detail for RAD21


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Basic Information Top
Gene Symbol:RAD21 ( FLJ25655,FLJ40596,HR21,HRAD21,KIAA0078,MCD1,NXP1,SCC1,hHR21 )
Gene Full Name: RAD21 homolog (S. pombe)
Band: 8q24.11
Quick LinksEntrez ID:5885; OMIM: 606462; Uniprot ID:RAD21_HUMAN; ENSEMBL ID: ENSG00000164754; HGNC ID: 9811
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body18 / 70761254
blastocyst16 / 62319256
fetus132 / 564012234
neonate4 / 31097128
infant5 / 23620211
juvenile14 / 55556251
adult365 / 1939121188
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor6 / 12794468
bladder carcinoma9 / 17475515
breast (mammary gland) tumor26 / 94178276
cervical tumor10 / 34366290
chondrosarcoma10 / 82823120
colorectal tumor16 / 114246140
esophageal tumor5 / 17290289
gastrointestinal tumor36 / 119369301
germ cell tumor116 / 263845439
glioma18 / 106883168
head and neck tumor34 / 136302249
kidney tumor16 / 68959232
leukemia32 / 95842333
liver tumor24 / 96359249
lung tumor5 / 10312748
lymphoma21 / 71755292
non-neoplasia17 / 97250174
normal681 / 3360307202
ovarian tumor19 / 76682247
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS22 / 125680175
prostate cancer21 / 102680204
retinoblastoma8 / 46356172
skin tumor19 / 124949152
soft tissue/muscle tissue tumor14 / 125191111
uterine tumor15 / 90257166
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland6 / 33197180
ascites13 / 40015324
bladder13 / 29757436
blood24 / 123478194
bone12 / 71655167
bone marrow23 / 48801471
brain314 / 1100989285
cervix11 / 48171228
connective tissue21 / 149255140
ear2 / 16212123
embryonic tissue42 / 215722194
esophagus6 / 20209296
eye30 / 211054142
heart12 / 89626133
intestine37 / 234472157
kidney40 / 211777188
larynx1 / 2414541
liver39 / 207743187
lung25 / 33697474
lymph13 / 44270293
lymph node56 / 91610611
mammary gland35 / 153271228
mouth35 / 67052521
muscle15 / 107715139
nerve0 / 157680 
ovary19 / 102051186
pancreas11 / 21481251
parathyroid3 / 20539146
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta62 / 280825220
prostate28 / 189345147
salivary gland11 / 20155545
skin22 / 210574104
spleen10 / 53952185
stomach25 / 96619258
testis163 / 330442493
thymus44 / 81131542
thyroid6 / 47473126
tonsil1 / 1699958
trachea27 / 52413515
umbilical cord3 / 13680219
uterus48 / 232878206
vascular7 / 51780135
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 200607_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts832.55
Adipocyte59.1
AdrenalCortex53.55
Adrenalgland46.1
Amygdala60.4
Appendix72.2
AtrioventricularNode18.7
BDCA4+_DentriticCells141.35
Bonemarrow44.55
BronchialEpithelialCells60.4
CD105+_Endothelial101.3
CD14+_Monocytes69
CD19+_BCells(neg._sel.)102.4
CD33+_Myeloid102.75
CD34+182
CD4+_Tcells181.1
CD56+_NKCells139.65
CD71+_EarlyErythroid517.5
CD8+_Tcells147.9
CardiacMyocytes132.55
Caudatenucleus56.55
Cerebellum71.35
CerebellumPeduncles76.1
CiliaryGanglion20.15
CingulateCortex75.8
Colorectaladenocarcinoma58.85
DorsalRootGanglion30.55
FetalThyroid55
Fetalbrain66.8
Fetalliver99.1
Fetallung58.75
GlobusPallidus49.9
Heart58.35
Hypothalamus59.85
Kidney37.7
Leukemia_chronicMyelogenousK-56240.8
Leukemia_promyelocytic-HL-60148.3
Leukemialymphoblastic(MOLT-4)416.4
Liver40.85
Lung27.25
Lymphnode36.3
Lymphoma_burkitts(Daudi)157.3
Lymphoma_burkitts(Raji)86.6
MedullaOblongata87.05
OccipitalLobe92.95
OlfactoryBulb33.55
Ovary35.1
Pancreas46.9
PancreaticIslet55.05
ParietalLobe92.85
Pituitary65.65
Placenta49
Pons65.6
PrefrontalCortex57.5
Prostate34.15
Salivarygland45.6
SkeletalMuscle134.1
Skin29.1
SmoothMuscle52.3
Spinalcord53.45
SubthalamicNucleus54.1
SuperiorCervicalGanglion54.4
TemporalLobe64
Testis49.85
TestisGermCell156.55
TestisIntersitial107.35
TestisLeydigCell100.65
TestisSeminiferousTubule89.45
Thalamus43.7
Thymus53.35
Thyroid51.55
Tongue51.1
Tonsil68.15
Trachea44.85
TrigeminalGanglion28.95
Uterus24.95
UterusCorpus76
WholeBlood182.55
Wholebrain45.35
colon207.5
pineal_day178.04
pineal_night180.08
retina64.85
small_intestine99.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P195137
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.25 ± 0.36
Basal Forebrain4.56 ± 0.22
Basal Part of Pons4.2 ± 0.61
Cerebellar Cortex4.57 ± 0.37
Cerebellar Nuclei4.03 ± 0.34
Claustrum4.03 ± 0.71
Epithalamus4.11 ± 0.32
Frontal Lobe4.2 ± 0.47
Globus Pallidus4.21 ± 0.63
Hypothalamus4.5 ± 0.76
Insula4.47 ± 0.44
Limbic Lobe4.35 ± 0.48
Mesencephalon4.41 ± 0.52
Myelencephalon4.3 ± 0.49
Occipital Lobe4.56 ± 0.43
Parietal Lobe4.29 ± 0.48
Pontine Tegmentum4.28 ± 0.53
Striatum4.59 ± 0.46
Subthalamus4.14 ± 0.33
Temporal Lobe4.21 ± 0.48
Thalamus4.21 ± 0.48
White Matter4.96 ± 0.45
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rad21CBCerebellum100
100
Rad21CTXCerebral cortex100
100
Rad21HIPHippocampal region100
100
Rad21HPFHippocampal formation100
100
Rad21HYHypothalamus100
100
Rad21LSXLateral septal complex100
100
Rad21MBMidbrain100
100
Rad21MYMedulla100
100
Rad21OLFOlfactory bulb100
100
Rad21PPons100
100
Rad21PALPallidum100
100
Rad21RHPRetrohippocampal region100
100
Rad21sAMYStriatum-like amygdalar nuclei100
100
Rad21STRStriatum100
100
Rad21STRdStriatum dorsal region100
100
Rad21STRvStriatum ventral region100
100
Rad21THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00009585 11 392 402 CLTPLVPEDLR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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