AutismKB 2.0

Annotation Detail for RAGE


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:RAGE ( MOK,RAGE1 )
Gene Full Name: renal tumor antigen
Band: 14q32
Quick LinksEntrez ID:5891; OMIM: 605762; Uniprot ID:MOK_HUMAN; ENSEMBL ID: ENSG00000080823; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus22 / 56401239
neonate0 / 310970 
infant1 / 2362042
juvenile1 / 5555617
adult68 / 193912135
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor3 / 3436687
chondrosarcoma6 / 8282372
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor10 / 11936983
germ cell tumor3 / 26384511
glioma0 / 1068830 
head and neck tumor5 / 13630236
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor26 / 96359269
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia8 / 9725082
normal138 / 336030741
ovarian tumor1 / 7668213
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS13 / 125680103
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor23 / 124949184
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites2 / 4001549
bladder0 / 297570 
blood2 / 12347816
bone9 / 71655125
bone marrow1 / 4880120
brain43 / 110098939
cervix4 / 4817183
connective tissue9 / 14925560
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye13 / 21105461
heart3 / 8962633
intestine3 / 23447212
kidney2 / 2117779
larynx1 / 2414541
liver37 / 207743178
lung10 / 33697429
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth1 / 6705214
muscle2 / 10771518
nerve0 / 157680 
ovary4 / 10205139
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta1 / 2808253
prostate5 / 18934526
salivary gland2 / 2015599
skin31 / 210574147
spleen0 / 539520 
stomach12 / 96619124
testis44 / 330442133
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus9 / 23287838
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205130_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.55
Adipocyte4.95
AdrenalCortex5.05
Adrenalgland4.25
Amygdala5.75
Appendix4.95
AtrioventricularNode3.6
BDCA4+_DentriticCells5.1
Bonemarrow4.85
BronchialEpithelialCells5
CD105+_Endothelial5
CD14+_Monocytes4.95
CD19+_BCells(neg._sel.)5.25
CD33+_Myeloid6
CD34+6
CD4+_Tcells5.45
CD56+_NKCells6
CD71+_EarlyErythroid4.65
CD8+_Tcells4.7
CardiacMyocytes6.25
Caudatenucleus5.4
Cerebellum4.1
CerebellumPeduncles5.8
CiliaryGanglion3.4
CingulateCortex5.25
Colorectaladenocarcinoma5.05
DorsalRootGanglion3.75
FetalThyroid5.2
Fetalbrain7.4
Fetalliver4.3
Fetallung4.1
GlobusPallidus3.45
Heart7.95
Hypothalamus7.6
Kidney4.05
Leukemia_chronicMyelogenousK-5624.6
Leukemia_promyelocytic-HL-604.9
Leukemialymphoblastic(MOLT-4)4.05
Liver6.7
Lung7.5
Lymphnode4.35
Lymphoma_burkitts(Daudi)6.45
Lymphoma_burkitts(Raji)7
MedullaOblongata4.5
OccipitalLobe5.1
OlfactoryBulb3.95
Ovary3.4
Pancreas3.95
PancreaticIslet5.35
ParietalLobe5.2
Pituitary6.85
Placenta5.1
Pons4.65
PrefrontalCortex6.25
Prostate6.35
Salivarygland4
SkeletalMuscle7.8
Skin3.7
SmoothMuscle8.2
Spinalcord5.4
SubthalamicNucleus4.5
SuperiorCervicalGanglion6.4
TemporalLobe4.55
Testis30.9
TestisGermCell12.5
TestisIntersitial27
TestisLeydigCell12.65
TestisSeminiferousTubule15.5
Thalamus5.1
Thymus3.9
Thyroid14.95
Tongue4.85
Tonsil4.55
Trachea4.2
TrigeminalGanglion4.85
Uterus4.1
UterusCorpus4.55
WholeBlood5.4
Wholebrain4.6
colon5
pineal_day6.26
pineal_night6.22
retina14.55
small_intestine4.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16325_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.74 ± 0.62
Basal Forebrain3.6 ± 0.31
Basal Part of Pons3.24 ± 0.38
Cerebellar Cortex3.28 ± 0.56
Cerebellar Nuclei3.31 ± 0.42
Claustrum3.7 ± 0.93
Epithalamus4.28 ± 0.82
Frontal Lobe3.57 ± 0.62
Globus Pallidus3.46 ± 0.54
Hypothalamus3.5 ± 0.55
Insula3.44 ± 0.79
Limbic Lobe3.85 ± 0.63
Mesencephalon3.69 ± 0.69
Myelencephalon3.63 ± 0.66
Occipital Lobe3.9 ± 0.43
Parietal Lobe3.72 ± 0.58
Pontine Tegmentum3.64 ± 0.57
Striatum3.65 ± 0.7
Subthalamus3.5 ± 0.3
Temporal Lobe3.63 ± 0.55
Thalamus3.43 ± 0.63
White Matter2.41 ± 0.11
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
RagesAMYStriatum-like amygdalar nuclei58.46
38.53
RageSTRdStriatum dorsal region38.42
26.19
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018