AutismKB 2.0

Annotation Detail for RANGAP1


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Basic Information Top
Gene Symbol:RANGAP1 ( Fug1,KIAA1835,MGC20266,SD )
Gene Full Name: Ran GTPase activating protein 1
Band: 22q13.2
Quick LinksEntrez ID:5905; OMIM: 602362; Uniprot ID:RAGP1_HUMAN; ENSEMBL ID: ENSG00000100401; HGNC ID: 9854
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body13 / 70761183
blastocyst17 / 62319272
fetus56 / 56401299
neonate4 / 31097128
infant3 / 23620127
juvenile3 / 5555653
adult183 / 193912194
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor21 / 94178222
cervical tumor2 / 3436658
chondrosarcoma22 / 82823265
colorectal tumor24 / 114246210
esophageal tumor2 / 17290115
gastrointestinal tumor14 / 119369117
germ cell tumor21 / 26384579
glioma24 / 106883224
head and neck tumor12 / 13630288
kidney tumor15 / 68959217
leukemia19 / 95842198
liver tumor9 / 9635993
lung tumor25 / 103127242
lymphoma11 / 71755153
non-neoplasia3 / 9725030
normal265 / 336030778
ovarian tumor5 / 7668265
pancreatic tumor13 / 104616124
primitive neuroectodermal tumor of the CNS35 / 125680278
prostate cancer15 / 102680146
retinoblastoma10 / 46356215
skin tumor97 / 124949776
soft tissue/muscle tissue tumor11 / 12519187
uterine tumor12 / 90257132
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland4 / 33197120
ascites5 / 40015124
bladder3 / 29757100
blood10 / 12347880
bone11 / 71655153
bone marrow6 / 48801122
brain128 / 1100989116
cervix2 / 4817141
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue37 / 215722171
esophagus2 / 2020998
eye29 / 211054137
heart7 / 8962678
intestine35 / 234472149
kidney16 / 21177775
larynx6 / 24145248
liver10 / 20774348
lung43 / 336974127
lymph10 / 44270225
lymph node6 / 9161065
mammary gland23 / 153271150
mouth4 / 6705259
muscle2 / 10771518
nerve3 / 15768190
ovary10 / 10205197
pancreas17 / 21481279
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta22 / 28082578
prostate15 / 18934579
salivary gland0 / 201550 
skin107 / 210574508
spleen3 / 5395255
stomach1 / 9661910
testis38 / 330442114
thymus5 / 8113161
thyroid2 / 4747342
tonsil4 / 16999235
trachea0 / 524130 
umbilical cord0 / 136800 
uterus22 / 23287894
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212127_at
Cell line Expression level Expression bar
721_B_lymphoblasts411.4
Adipocyte32.3
AdrenalCortex82
Adrenalgland48.45
Amygdala98.3
Appendix31.65
AtrioventricularNode31.4
BDCA4+_DentriticCells79
Bonemarrow34.05
BronchialEpithelialCells45
CD105+_Endothelial275.95
CD14+_Monocytes69.15
CD19+_BCells(neg._sel.)63.5
CD33+_Myeloid96
CD34+217.75
CD4+_Tcells128
CD56+_NKCells108.15
CD71+_EarlyErythroid363.15
CD8+_Tcells83.4
CardiacMyocytes49.9
Caudatenucleus61.9
Cerebellum30.3
CerebellumPeduncles53.15
CiliaryGanglion28.85
CingulateCortex87.6
Colorectaladenocarcinoma112.05
DorsalRootGanglion22.7
FetalThyroid31.6
Fetalbrain68.65
Fetalliver34
Fetallung25.9
GlobusPallidus64.65
Heart53.55
Hypothalamus156.7
Kidney44.9
Leukemia_chronicMyelogenousK-56260.95
Leukemia_promyelocytic-HL-6054.55
Leukemialymphoblastic(MOLT-4)72.2
Liver77.15
Lung49.1
Lymphnode22.65
Lymphoma_burkitts(Daudi)95.65
Lymphoma_burkitts(Raji)110.3
MedullaOblongata73.4
OccipitalLobe80.15
OlfactoryBulb42.75
Ovary17.7
Pancreas40
PancreaticIslet82.85
ParietalLobe74.95
Pituitary34.9
Placenta46.1
Pons57.35
PrefrontalCortex231.35
Prostate46.4
Salivarygland38.5
SkeletalMuscle49.25
Skin26.35
SmoothMuscle41.25
Spinalcord67.65
SubthalamicNucleus78.8
SuperiorCervicalGanglion34.45
TemporalLobe97.25
Testis143.05
TestisGermCell53.5
TestisIntersitial30.35
TestisLeydigCell42.35
TestisSeminiferousTubule45.9
Thalamus114.05
Thymus60
Thyroid33.55
Tongue32.2
Tonsil38.05
Trachea21.8
TrigeminalGanglion26.7
Uterus12.7
UterusCorpus24.75
WholeBlood23
Wholebrain107.15
colon19
pineal_day192.84
pineal_night181.48
retina57.725
small_intestine25.4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6938_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.95 ± 0.53
Basal Forebrain9.5 ± 0.45
Basal Part of Pons10.03 ± 0.57
Cerebellar Cortex8.69 ± 0.36
Cerebellar Nuclei9.11 ± 0.48
Claustrum10.46 ± 0.72
Epithalamus8.09 ± 0.7
Frontal Lobe9.18 ± 0.65
Globus Pallidus9.93 ± 0.47
Hypothalamus8.96 ± 0.72
Insula9.23 ± 0.66
Limbic Lobe9.82 ± 0.68
Mesencephalon9.45 ± 0.57
Myelencephalon9.42 ± 0.63
Occipital Lobe9.87 ± 0.6
Parietal Lobe9.5 ± 0.69
Pontine Tegmentum9.11 ± 0.55
Striatum9.94 ± 0.53
Subthalamus9.33 ± 0.39
Temporal Lobe9.45 ± 0.55
Thalamus9.16 ± 0.56
White Matter9.9 ± 0.61
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rangap1CBCerebellum100
100
Rangap1CTXCerebral cortex100
100
Rangap1HIPHippocampal region100
100
Rangap1HPFHippocampal formation100
100
Rangap1HYHypothalamus100
100
Rangap1LSXLateral septal complex100
100
Rangap1MBMidbrain100
100
Rangap1MYMedulla100
100
Rangap1OLFOlfactory bulb100
100
Rangap1PPons100
100
Rangap1PALPallidum100
100
Rangap1RHPRetrohippocampal region100
100
Rangap1sAMYStriatum-like amygdalar nuclei100
100
Rangap1STRStriatum100
100
Rangap1STRdStriatum dorsal region100
100
Rangap1STRvStriatum ventral region100
100
Rangap1THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00001063 10 82 91 CHWSDMFTGR Peptide Atlas
RAGP1_HUMAN_15 11 15 25 TQVAGGQLSFK PRIDE
RAGP1_HUMAN_265 13 265 277 QVEVINFGDCLVR PRIDE
RAGP1_HUMAN_278 12 278 289 SKGAVAIADAIR PRIDE
RAGP1_HUMAN_414 32 414 445 ILDPNTGEPAPVLSSPPPADVSTFLAFPSPEK PRIDE
RAGP1_HUMAN_475 12 475 486 VSSVFKDEATVR PRIDE
RAGP1_HUMAN_487 13 487 499 MAVQDAVDALMQK PRIDE
RAGP1_HUMAN_516 9 516 524 LLVHMGLLK PRIDE
RAGP1_HUMAN_530 23 530 552 AIANLYGPLMALNHMVQQDYFPK PRIDE
RAGP1_HUMAN_553 24 553 576 ALAPLLLAFVTKPNSALESCSFAR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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