AutismKB 2.0

Annotation Detail for ENPP5


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Basic Information Top
Gene Symbol:ENPP5 ( KIAA0879 )
Gene Full Name: ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)
Band: 6p21.1
Quick LinksEntrez ID:59084; OMIM: NA; Uniprot ID:ENPP5_HUMAN; ENSEMBL ID: ENSG00000112796; HGNC ID: 13717
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus7 / 56401212
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult38 / 193912119
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor14 / 94178148
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor8 / 11424670
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor1 / 2638453
glioma5 / 10688346
head and neck tumor12 / 13630288
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal123 / 336030736
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain96 / 110098987
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye1 / 2110544
heart1 / 8962611
intestine8 / 23447234
kidney5 / 21177723
larynx0 / 241450 
liver1 / 2077434
lung13 / 33697438
lymph0 / 442700 
lymph node1 / 9161010
mammary gland14 / 15327191
mouth12 / 67052178
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid4 / 20539194
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta0 / 2808250 
prostate6 / 18934531
salivary gland0 / 201550 
skin2 / 2105749
spleen3 / 5395255
stomach0 / 966190 
testis34 / 330442102
thymus3 / 8113136
thyroid0 / 474730 
tonsil0 / 169990 
trachea7 / 52413133
umbilical cord0 / 136800 
uterus4 / 23287817
vascular3 / 5178057
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1145_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.86 ± 0.3
Basal Forebrain7.73 ± 0.35
Basal Part of Pons8.29 ± 0.29
Cerebellar Cortex7.98 ± 0.27
Cerebellar Nuclei8.07 ± 0.55
Claustrum8.13 ± 0.36
Epithalamus7.82 ± 0.31
Frontal Lobe8.19 ± 0.36
Globus Pallidus8.4 ± 0.38
Hypothalamus8 ± 0.36
Insula8.07 ± 0.22
Limbic Lobe8.19 ± 0.36
Mesencephalon8.3 ± 0.41
Myelencephalon8.08 ± 0.36
Occipital Lobe8.63 ± 0.36
Parietal Lobe8.35 ± 0.33
Pontine Tegmentum8.18 ± 0.3
Striatum7.76 ± 0.32
Subthalamus8.35 ± 0.26
Temporal Lobe8.09 ± 0.31
Thalamus8.48 ± 0.32
White Matter7.04 ± 0.5
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Enpp5CBCerebellum56.69
100
Enpp5CTXCerebral cortex100
100
Enpp5HIPHippocampal region100
100
Enpp5HPFHippocampal formation100
100
Enpp5HYHypothalamus100
100
Enpp5LSXLateral septal complex100
100
Enpp5MBMidbrain100
100
Enpp5MYMedulla100
100
Enpp5OLFOlfactory bulb100
100
Enpp5PPons100
100
Enpp5PALPallidum100
100
Enpp5RHPRetrohippocampal region100
100
Enpp5sAMYStriatum-like amygdalar nuclei100
100
Enpp5STRStriatum100
100
Enpp5STRdStriatum dorsal region100
100
Enpp5STRvStriatum ventral region100
100
Enpp5THThalamus100
100
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018