Annotation Detail for RBL1
Basic Information Top
| Gene Symbol: | RBL1 ( CP107,MGC40006,PRB1,p107 ) |
|---|---|
| Gene Full Name: | retinoblastoma-like 1 (p107) |
| Band: | 20q11.23 |
| Quick Links | Entrez ID:5933; OMIM: 116957; Uniprot ID:RBL1_HUMAN; ENSEMBL ID: ENSG00000080839; HGNC ID: 9893 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.207745
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 1 / 70761 | 14 |  |
| blastocyst | 2 / 62319 | 32 | |
| fetus | 8 / 564012 | 14 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 2 / 55556 | 35 | |
| adult | 22 / 1939121 | 11 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 3 / 94178 | 31 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 6 / 263845 | 22 | |
| glioma | 1 / 106883 | 9 |  |
| head and neck tumor | 5 / 136302 | 36 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 3 / 95842 | 31 | |
| liver tumor | 2 / 96359 | 20 | |
| lung tumor | 1 / 103127 | 9 | |
| lymphoma | 1 / 71755 | 13 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 33 / 3360307 | 9 | |
| ovarian tumor | 1 / 76682 | 13 | |
| pancreatic tumor | 1 / 104616 | 9 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 1 / 102680 | 9 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 3 / 124949 | 24 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 3 / 90257 | 33 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 3 / 123478 | 24 | |
| bone | 1 / 71655 | 13 | |
| bone marrow | 1 / 48801 | 20 | |
| brain | 4 / 1100989 | 3 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 5 / 215722 | 23 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 3 / 211054 | 14 | |
| heart | 2 / 89626 | 22 | |
| intestine | 0 / 234472 | 0 | |
| kidney | 0 / 211777 | 0 | |
| larynx | 0 / 24145 | 0 | |
| liver | 4 / 207743 | 19 | |
| lung | 1 / 336974 | 2 | |
| lymph | 1 / 44270 | 22 | |
| lymph node | 2 / 91610 | 21 | |
| mammary gland | 3 / 153271 | 19 | |
| mouth | 5 / 67052 | 74 |  |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 2 / 102051 | 19 | |
| pancreas | 1 / 214812 | 4 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 1 / 280825 | 3 | |
| prostate | 2 / 189345 | 10 | |
| salivary gland | 1 / 20155 | 49 | |
| skin | 8 / 210574 | 37 | |
| spleen | 1 / 53952 | 18 | |
| stomach | 0 / 96619 | 0 | |
| testis | 5 / 330442 | 15 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 1 / 52413 | 19 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 3 / 232878 | 12 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 205296_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 10.55 | |
| Adipocyte | 8.1 | |
| AdrenalCortex | 13.1 | |
| Adrenalgland | 8.15 | |
| Amygdala | 8 | |
| Appendix | 13.9 | |
| AtrioventricularNode | 12.75 | |
| BDCA4+_DentriticCells | 8.05 | |
| Bonemarrow | 11.1 | |
| BronchialEpithelialCells | 7.85 | |
| CD105+_Endothelial | 11.85 | |
| CD14+_Monocytes | 9.25 | |
| CD19+_BCells(neg._sel.) | 8.4 | |
| CD33+_Myeloid | 10.45 | |
| CD34+ | 10.15 | |
| CD4+_Tcells | 7.9 | |
| CD56+_NKCells | 10.1 | |
| CD71+_EarlyErythroid | 8.65 | |
| CD8+_Tcells | 9.1 | |
| CardiacMyocytes | 20.3 | |
| Caudatenucleus | 7.5 | |
| Cerebellum | 7.05 | |
| CerebellumPeduncles | 11.3 | |
| CiliaryGanglion | 10.55 | |
| CingulateCortex | 9.6 | |
| Colorectaladenocarcinoma | 11.05 | |
| DorsalRootGanglion | 10.15 | |
| FetalThyroid | 9.5 | |
| Fetalbrain | 7.7 | |
| Fetalliver | 8.2 | |
| Fetallung | 5.65 | |
| GlobusPallidus | 8.05 | |
| Heart | 18.65 | |
| Hypothalamus | 8.2 | |
| Kidney | 8.55 | |
| Leukemia_chronicMyelogenousK-562 | 7.5 | |
| Leukemia_promyelocytic-HL-60 | 7.6 | |
| Leukemialymphoblastic(MOLT-4) | 10.65 | |
| Liver | 15 | |
| Lung | 8.95 | |
| Lymphnode | 6.7 | |
| Lymphoma_burkitts(Daudi) | 12.1 | |
| Lymphoma_burkitts(Raji) | 14.65 | |
| MedullaOblongata | 7.1 | |
| OccipitalLobe | 7.6 | |
| OlfactoryBulb | 6.4 | |
| Ovary | 7.7 | |
| Pancreas | 7.75 | |
| PancreaticIslet | 9.3 | |
| ParietalLobe | 10.65 | |
| Pituitary | 9.95 | |
| Placenta | 7.9 | |
| Pons | 9.05 | |
| PrefrontalCortex | 9.75 | |
| Prostate | 9.55 | |
| Salivarygland | 7.75 | |
| SkeletalMuscle | 16.1 | |
| Skin | 10.6 | |
| SmoothMuscle | 9.7 | |
| Spinalcord | 8.5 | |
| SubthalamicNucleus | 9.5 | |
| SuperiorCervicalGanglion | 19.85 | |
| TemporalLobe | 9 | |
| Testis | 7 | |
| TestisGermCell | 6.5 | |
| TestisIntersitial | 9.3 | |
| TestisLeydigCell | 9.6 | |
| TestisSeminiferousTubule | 7.4 | |
| Thalamus | 9.5 | |
| Thymus | 6 | |
| Thyroid | 9.65 | |
| Tongue | 12.25 | |
| Tonsil | 9.8 | |
| Trachea | 6.85 | |
| TrigeminalGanglion | 15.95 | |
| Uterus | 6.3 | |
| UterusCorpus | 10.95 | |
| WholeBlood | 8.65 | |
| Wholebrain | 6.45 | |
| colon | 8.45 | |
| pineal_day | 10.08 | |
| pineal_night | 9.66 | |
| retina | 10.05 | |
| small_intestine | 7.5 | |
- Probe name: CUST_12220_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 2.09 ± 0.99 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 1.62 ± 0.26 | |
| Basal Part of Pons | 1.41 ± 0.58 | |
| Cerebellar Cortex | 2.25 ± 0.39 | |
| Cerebellar Nuclei | 1.99 ± 1 | |
| Claustrum | 2.29 ± 0.67 | |
| Epithalamus | 1.59 ± 0.62 | |
| Frontal Lobe | 1.49 ± 0.66 | |
| Globus Pallidus | 1.9 ± 0.63 | |
| Hypothalamus | 1.79 ± 0.68 | |
| Insula | 1.8 ± 1.11 | |
| Limbic Lobe | 1.55 ± 0.63 | |
| Mesencephalon | 1.79 ± 0.71 | |
| Myelencephalon | 1.68 ± 0.67 | |
| Occipital Lobe | 2.01 ± 0.86 | |
| Parietal Lobe | 1.58 ± 0.68 | |
| Pontine Tegmentum | 1.77 ± 0.71 | |
| Striatum | 1.49 ± 0.68 | |
| Subthalamus | 1.79 ± 0.71 | |
| Temporal Lobe | 1.49 ± 0.65 | |
| Thalamus | 1.6 ± 0.6 | |
| White Matter | 2 ± 0.73 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Rbl1 | CB | Cerebellum | 0.49 | |
| 0.58 | | |||
| Rbl1 | CTX | Cerebral cortex | 0.26 | |
| 0.26 | | |||
| Rbl1 | HIP | Hippocampal region | 0.88 | |
| 1.71 | | |||
| Rbl1 | HPF | Hippocampal formation | 0.65 | |
| 0.99 | | |||
| Rbl1 | HY | Hypothalamus | 0.45 | |
| 0.99 | | |||
| Rbl1 | LSX | Lateral septal complex | 0.09 | |
| 0.08 | | |||
| Rbl1 | MB | Midbrain | 0.28 | |
| 0.27 | | |||
| Rbl1 | MY | Medulla | 0.29 | |
| 0.23 | | |||
| Rbl1 | OLF | Olfactory bulb | 0.33 | |
| 0.58 | | |||
| Rbl1 | P | Pons | 0.22 | |
| 0.48 | | |||
| Rbl1 | PAL | Pallidum | 0.11 | |
| 0.1 | | |||
| Rbl1 | RHP | Retrohippocampal region | 0.35 | |
| 0.22 | | |||
| Rbl1 | sAMY | Striatum-like amygdalar nuclei | 0.25 | |
| 0.09 | | |||
| Rbl1 | STR | Striatum | 0.13 | |
| 0.12 | | |||
| Rbl1 | STRd | Striatum dorsal region | 0.11 | |
| 0.11 | | |||
| Rbl1 | STRv | Striatum ventral region | 0.14 | |
| 0.18 | | |||
| Rbl1 | TH | Thalamus | 0.51 | |
| 0.59 | |
Peptide