AutismKB 2.0

Annotation Detail for ALOXE3


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ALOXE3 ( E-LOX,MGC119694,MGC119695,MGC119696,eLOX3 )
Gene Full Name: arachidonate lipoxygenase 3
Band: 17p13.1
Quick LinksEntrez ID:59344; OMIM: 607206; Uniprot ID:LOXE3_HUMAN; ENSEMBL ID: ENSG00000179148; HGNC ID: 13743
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus3 / 5640125
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult5 / 19391212
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor4 / 26384515
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal19 / 33603075
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain12 / 110098910
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye2 / 2110549
heart0 / 896260 
intestine1 / 2344724
kidney2 / 2117779
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta2 / 2808257
prostate0 / 1893450 
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach0 / 966190 
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 222383_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.95
Adipocyte5.05
AdrenalCortex5.9
Adrenalgland4.5
Amygdala5.2
Appendix11.9
AtrioventricularNode4.35
BDCA4+_DentriticCells5.2
Bonemarrow5.5
BronchialEpithelialCells5
CD105+_Endothelial5.05
CD14+_Monocytes5.4
CD19+_BCells(neg._sel.)5.25
CD33+_Myeloid6.35
CD34+6.15
CD4+_Tcells5.25
CD56+_NKCells5.85
CD71+_EarlyErythroid4.85
CD8+_Tcells4.65
CardiacMyocytes7.35
Caudatenucleus4.65
Cerebellum4.2
CerebellumPeduncles6
CiliaryGanglion3.9
CingulateCortex7.15
Colorectaladenocarcinoma5.15
DorsalRootGanglion4.2
FetalThyroid5.05
Fetalbrain4.95
Fetalliver4.6
Fetallung4.05
GlobusPallidus3.85
Heart7.25
Hypothalamus5.4
Kidney4.55
Leukemia_chronicMyelogenousK-5624.65
Leukemia_promyelocytic-HL-604.5
Leukemialymphoblastic(MOLT-4)4
Liver7.15
Lung5.55
Lymphnode4.2
Lymphoma_burkitts(Daudi)6.8
Lymphoma_burkitts(Raji)7.65
MedullaOblongata6.55
OccipitalLobe4.55
OlfactoryBulb4
Ovary3.7
Pancreas4.25
PancreaticIslet5.5
ParietalLobe5.6
Pituitary5.95
Placenta5.1
Pons5.55
PrefrontalCortex6.15
Prostate5.8
Salivarygland7.45
SkeletalMuscle18.15
Skin4.5
SmoothMuscle5.7
Spinalcord5.5
SubthalamicNucleus4.85
SuperiorCervicalGanglion26.7
TemporalLobe4.8
Testis4.4
TestisGermCell4.05
TestisIntersitial4.3
TestisLeydigCell5.25
TestisSeminiferousTubule4.35
Thalamus5.65
Thymus3.9
Thyroid6.2
Tongue5.3
Tonsil5.05
Trachea4.3
TrigeminalGanglion5.9
Uterus4.05
UterusCorpus4.85
WholeBlood5.55
Wholebrain4.35
colon5.1
pineal_day6.26
pineal_night6.16
retina6.175
small_intestine4.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_11076_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.22 ± 1.01
Basal Forebrain1.78 ± 0.21
Basal Part of Pons1.53 ± 0.43
Cerebellar Cortex1.61 ± 0.65
Cerebellar Nuclei2.19 ± 0.76
Claustrum2.67 ± 0.87
Epithalamus1.49 ± 0.66
Frontal Lobe1.62 ± 0.62
Globus Pallidus2.38 ± 0.31
Hypothalamus1.83 ± 0.68
Insula1.67 ± 0.55
Limbic Lobe1.8 ± 0.62
Mesencephalon1.92 ± 0.67
Myelencephalon1.82 ± 0.65
Occipital Lobe1.85 ± 0.61
Parietal Lobe1.8 ± 0.77
Pontine Tegmentum1.82 ± 0.64
Striatum1.99 ± 0.56
Subthalamus1.89 ± 0.6
Temporal Lobe1.69 ± 0.61
Thalamus1.76 ± 0.58
White Matter2.4 ± 0.42
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Aloxe3CBCerebellum0.74
1.33
Aloxe3CTXCerebral cortex1.03
1.23
Aloxe3HIPHippocampal region1.31
1.54
Aloxe3HPFHippocampal formation1.07
1.15
Aloxe3HYHypothalamus0.24
0.32
Aloxe3LSXLateral septal complex0.56
0.58
Aloxe3MBMidbrain0.51
0.89
Aloxe3MYMedulla0.36
0.84
Aloxe3OLFOlfactory bulb0.82
1.04
Aloxe3PPons0.58
0.99
Aloxe3PALPallidum0.36
0.69
Aloxe3RHPRetrohippocampal region0.58
0.58
Aloxe3sAMYStriatum-like amygdalar nuclei0.91
1.05
Aloxe3STRStriatum0.41
0.45
Aloxe3STRdStriatum dorsal region0.37
0.41
Aloxe3STRvStriatum ventral region0.11
0.13
Aloxe3THThalamus0.46
0.71
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved