Annotation Detail for GNB4
Basic Information Top
| Gene Symbol: | GNB4 ( - ) |
|---|---|
| Gene Full Name: | guanine nucleotide binding protein (G protein), beta polypeptide 4 |
| Band: | 3q26.33 |
| Quick Links | Entrez ID:59345; OMIM: 610863; Uniprot ID:GBB4_HUMAN; ENSEMBL ID: ENSG00000114450; HGNC ID: 20731 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.173030
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 7 / 70761 | 98 |  |
| blastocyst | 4 / 62319 | 64 | |
| fetus | 37 / 564012 | 65 | |
| neonate | 0 / 31097 | 0 | |
| infant | 1 / 23620 | 42 |  |
| juvenile | 2 / 55556 | 35 | |
| adult | 71 / 1939121 | 36 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 1 / 17475 | 57 | |
| breast (mammary gland) tumor | 1 / 94178 | 10 |  |
| cervical tumor | 2 / 34366 | 58 | |
| chondrosarcoma | 7 / 82823 | 84 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 2 / 119369 | 16 | |
| germ cell tumor | 21 / 263845 | 79 | |
| glioma | 9 / 106883 | 84 | |
| head and neck tumor | 2 / 136302 | 14 | |
| kidney tumor | 3 / 68959 | 43 | |
| leukemia | 3 / 95842 | 31 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 1 / 103127 | 9 | |
| lymphoma | 2 / 71755 | 27 | |
| non-neoplasia | 3 / 97250 | 30 | |
| normal | 117 / 3360307 | 34 | |
| ovarian tumor | 3 / 76682 | 39 | |
| pancreatic tumor | 6 / 104616 | 57 | |
| primitive neuroectodermal tumor of the CNS | 3 / 125680 | 23 | |
| prostate cancer | 6 / 102680 | 58 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 4 / 124949 | 32 | |
| soft tissue/muscle tissue tumor | 7 / 125191 | 55 | |
| uterine tumor | 1 / 90257 | 11 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 1 / 123478 | 8 | |
| bone | 2 / 71655 | 27 | |
| bone marrow | 3 / 48801 | 61 | |
| brain | 43 / 1100989 | 39 | |
| cervix | 2 / 48171 | 41 | |
| connective tissue | 7 / 149255 | 46 | |
| ear | 3 / 16212 | 185 | |
| embryonic tissue | 14 / 215722 | 64 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 5 / 211054 | 23 | |
| heart | 3 / 89626 | 33 | |
| intestine | 6 / 234472 | 25 | |
| kidney | 3 / 211777 | 14 | |
| larynx | 1 / 24145 | 41 | |
| liver | 2 / 207743 | 9 | |
| lung | 10 / 336974 | 29 | |
| lymph | 1 / 44270 | 22 | |
| lymph node | 2 / 91610 | 21 | |
| mammary gland | 1 / 153271 | 6 | |
| mouth | 1 / 67052 | 14 | |
| muscle | 2 / 107715 | 18 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 1 / 102051 | 9 | |
| pancreas | 6 / 214812 | 27 | |
| parathyroid | 1 / 20539 | 48 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 24 / 280825 | 85 | |
| prostate | 8 / 189345 | 42 | |
| salivary gland | 2 / 20155 | 99 | |
| skin | 8 / 210574 | 37 | |
| spleen | 1 / 53952 | 18 | |
| stomach | 1 / 96619 | 10 | |
| testis | 10 / 330442 | 30 | |
| thymus | 1 / 81131 | 12 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 2 / 13680 | 146 | |
| uterus | 10 / 232878 | 42 | |
| vascular | 5 / 51780 | 96 | |
Microarray in - Probe name: A_24_P835921
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 2.12 ± 1.07 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 1.63 ± 0.23 | |
| Basal Part of Pons | 1.39 ± 0.36 | |
| Cerebellar Cortex | 2.27 ± 0.65 | |
| Cerebellar Nuclei | 1.96 ± 0.74 | |
| Claustrum | 2.58 ± 0.53 | |
| Epithalamus | 1.56 ± 0.7 | |
| Frontal Lobe | 1.79 ± 0.74 | |
| Globus Pallidus | 1.63 ± 0.54 | |
| Hypothalamus | 1.85 ± 0.85 | |
| Insula | 1.91 ± 0.71 | |
| Limbic Lobe | 1.66 ± 0.65 | |
| Mesencephalon | 1.94 ± 0.77 | |
| Myelencephalon | 1.82 ± 0.69 | |
| Occipital Lobe | 1.64 ± 0.67 | |
| Parietal Lobe | 1.63 ± 0.65 | |
| Pontine Tegmentum | 1.83 ± 0.66 | |
| Striatum | 1.46 ± 0.68 | |
| Subthalamus | 1.85 ± 0.71 | |
| Temporal Lobe | 1.79 ± 0.71 | |
| Thalamus | 1.68 ± 0.62 | |
| White Matter | 2.38 ± 0.21 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Gnb4 | CB | Cerebellum | 7.72 | |
| 10.04 | | |||
| Gnb4 | CTX | Cerebral cortex | 10.57 | |
| 12.67 | | |||
| Gnb4 | HIP | Hippocampal region | 3.29 | |
| 3.75 | | |||
| Gnb4 | HPF | Hippocampal formation | 3.55 | |
| 3.45 | | |||
| Gnb4 | HY | Hypothalamus | 2.75 | |
| 2.66 | | |||
| Gnb4 | LSX | Lateral septal complex | 9.59 | |
| 7.7 | | |||
| Gnb4 | MB | Midbrain | 1.23 | |
| 1.32 | | |||
| Gnb4 | MY | Medulla | 1 | |
| 1.22 | | |||
| Gnb4 | OLF | Olfactory bulb | 11.18 | |
| 9.44 | | |||
| Gnb4 | P | Pons | 1.05 | |
| 0.98 | | |||
| Gnb4 | PAL | Pallidum | 2.84 | |
| 2.48 | | |||
| Gnb4 | RHP | Retrohippocampal region | 4.01 | |
| 3.14 | | |||
| Gnb4 | sAMY | Striatum-like amygdalar nuclei | 4.56 | |
| 3.39 | | |||
| Gnb4 | STR | Striatum | 8.24 | |
| 7.26 | | |||
| Gnb4 | STRd | Striatum dorsal region | 5.83 | |
| 6.56 | | |||
| Gnb4 | STRv | Striatum ventral region | 17.96 | |
| 11.6 | | |||
| Gnb4 | TH | Thalamus | 2.08 | |
| 2.02 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| GBB4_HUMAN_0 | 0 | 0 | 0 | LIIWDSYTTNK | PRIDE |
| GBB4_HUMAN_137 | 13 | 137 | 149 | ELPGHTGYLSCCR | PRIDE |
| GBB4_HUMAN_78 | 11 | 78 | 88 | LIIWDSYTTNK | PRIDE |
| PAp00000224 | 19 | 24 | 42 | ACNDATLVQITSNMDSVGR | Peptide Atlas |