AutismKB 2.0

Annotation Detail for RBM3


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Basic Information Top
Gene Symbol:RBM3 ( IS1-RNPL,RNPL )
Gene Full Name: RNA binding motif (RNP1, RRM) protein 3
Band: Xp11.23
Quick LinksEntrez ID:5935; OMIM: 300027; Uniprot ID:RBM3_HUMAN; ENSEMBL ID: ENSG00000102317; HGNC ID: 9900
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body28 / 70761395
blastocyst24 / 62319385
fetus41 / 56401272
neonate2 / 3109764
infant9 / 23620381
juvenile21 / 55556377
adult257 / 1939121132
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor11 / 94178116
cervical tumor24 / 34366698
chondrosarcoma1 / 8282312
colorectal tumor11 / 11424696
esophageal tumor3 / 17290173
gastrointestinal tumor37 / 119369309
germ cell tumor66 / 263845250
glioma12 / 106883112
head and neck tumor2 / 13630214
kidney tumor17 / 68959246
leukemia28 / 95842292
liver tumor65 / 96359674
lung tumor21 / 103127203
lymphoma17 / 71755236
non-neoplasia21 / 97250215
normal508 / 3360307151
ovarian tumor6 / 7668278
pancreatic tumor21 / 104616200
primitive neuroectodermal tumor of the CNS22 / 125680175
prostate cancer33 / 102680321
retinoblastoma5 / 46356107
skin tumor32 / 124949256
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue5 / 13106381
adrenal gland11 / 33197331
ascites14 / 40015349
bladder12 / 29757403
blood26 / 123478210
bone17 / 71655237
bone marrow18 / 48801368
brain152 / 1100989138
cervix25 / 48171518
connective tissue8 / 14925553
ear1 / 1621261
embryonic tissue74 / 215722343
esophagus3 / 20209148
eye25 / 211054118
heart18 / 89626200
intestine41 / 234472174
kidney27 / 211777127
larynx0 / 241450 
liver78 / 207743375
lung55 / 336974163
lymph5 / 44270112
lymph node15 / 91610163
mammary gland16 / 153271104
mouth2 / 6705229
muscle7 / 10771564
nerve0 / 157680 
ovary12 / 102051117
pancreas33 / 214812153
parathyroid4 / 20539194
pharynx16 / 41328387
pituitary gland1 / 1658560
placenta72 / 280825256
prostate53 / 189345279
salivary gland1 / 2015549
skin42 / 210574199
spleen14 / 53952259
stomach25 / 96619258
testis27 / 33044281
thymus39 / 81131480
thyroid3 / 4747363
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord1 / 1368073
uterus23 / 23287898
vascular13 / 51780251
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 208319_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts467.8
Adipocyte90.6
AdrenalCortex39.85
Adrenalgland30.3
Amygdala42.45
Appendix28.8
AtrioventricularNode22.8
BDCA4+_DentriticCells539.7
Bonemarrow100.55
BronchialEpithelialCells285.5
CD105+_Endothelial324.95
CD14+_Monocytes384.55
CD19+_BCells(neg._sel.)618
CD33+_Myeloid518
CD34+608.4
CD4+_Tcells343.2
CD56+_NKCells548.65
CD71+_EarlyErythroid100.7
CD8+_Tcells367.3
CardiacMyocytes225.35
Caudatenucleus19.95
Cerebellum13.8
CerebellumPeduncles27
CiliaryGanglion22.9
CingulateCortex19.1
Colorectaladenocarcinoma176.85
DorsalRootGanglion23.2
FetalThyroid26.2
Fetalbrain24.8
Fetalliver25.8
Fetallung24.5
GlobusPallidus15.7
Heart36.5
Hypothalamus37.35
Kidney19.25
Leukemia_chronicMyelogenousK-56223.65
Leukemia_promyelocytic-HL-6072.8
Leukemialymphoblastic(MOLT-4)48.25
Liver34.7
Lung45.65
Lymphnode108.05
Lymphoma_burkitts(Daudi)151.2
Lymphoma_burkitts(Raji)35.1
MedullaOblongata15.3
OccipitalLobe22.25
OlfactoryBulb20.5
Ovary27.6
Pancreas27.55
PancreaticIslet230.4
ParietalLobe27.5
Pituitary31.2
Placenta99.3
Pons24.65
PrefrontalCortex21.35
Prostate30.45
Salivarygland79.15
SkeletalMuscle32.8
Skin24.6
SmoothMuscle385.45
Spinalcord28.7
SubthalamicNucleus23.4
SuperiorCervicalGanglion33.8
TemporalLobe24.05
Testis22.65
TestisGermCell37.5
TestisIntersitial22.3
TestisLeydigCell27.2
TestisSeminiferousTubule23.2
Thalamus24.1
Thymus84.45
Thyroid134.2
Tongue27.95
Tonsil81.2
Trachea77.8
TrigeminalGanglion34.1
Uterus61.3
UterusCorpus24.65
WholeBlood270.95
Wholebrain15.9
colon280.75
pineal_day47.72
pineal_night71.3
retina378.5
small_intestine364.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6565_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.17 ± 0.44
Basal Forebrain5.07 ± 0.47
Basal Part of Pons5.32 ± 0.24
Cerebellar Cortex5.16 ± 0.3
Cerebellar Nuclei4.94 ± 0.3
Claustrum5.43 ± 0.4
Epithalamus4.62 ± 0.4
Frontal Lobe5.14 ± 0.39
Globus Pallidus5.48 ± 0.33
Hypothalamus5.21 ± 0.56
Insula5.28 ± 0.28
Limbic Lobe5.18 ± 0.37
Mesencephalon5.14 ± 0.28
Myelencephalon5.09 ± 0.42
Occipital Lobe5.29 ± 0.3
Parietal Lobe5.15 ± 0.41
Pontine Tegmentum5.14 ± 0.46
Striatum4.93 ± 0.4
Subthalamus4.91 ± 0.7
Temporal Lobe5.06 ± 0.35
Thalamus5.24 ± 0.35
White Matter5.24 ± 0.14
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rbm3CBCerebellum1.18
2.65
Rbm3CTXCerebral cortex2.39
1.92
Rbm3HIPHippocampal region4.87
4.44
Rbm3HPFHippocampal formation3.89
3.31
Rbm3HYHypothalamus2.78
2.12
Rbm3LSXLateral septal complex5.58
3.98
Rbm3MBMidbrain2.3
2.56
Rbm3MYMedulla0.33
0.64
Rbm3OLFOlfactory bulb2.74
2.68
Rbm3PPons2.31
2.82
Rbm3PALPallidum2.02
1.59
Rbm3RHPRetrohippocampal region2.45
1.83
Rbm3sAMYStriatum-like amygdalar nuclei0.45
0.5
Rbm3STRStriatum0.94
0.77
Rbm3STRdStriatum dorsal region0.21
0.26
Rbm3STRvStriatum ventral region1.87
1.32
Rbm3THThalamus1.49
1.2
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00034121 18 48 65 GFGFITFTNPEHASVAMR Peptide Atlas
RBM3_HUMAN_116 15 116 130 YYDSRPGGYGYGYGR PRIDE
RBM3_HUMAN_122 10 122 131 PGGYGYGYGR PRIDE
RBM3_HUMAN_47 18 47 64 GFGFITFTNPEHASVAMR PRIDE
RBM3_HUMAN_66 10 66 75 AMNGESLDGR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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