AutismKB 2.0

Annotation Detail for RDX


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Basic Information Top
Gene Symbol:RDX ( DFNB24 )
Gene Full Name: radixin
Band: 11q23
Quick LinksEntrez ID:5962; OMIM: 179410; Uniprot ID:RADI_HUMAN; ENSEMBL ID: ENSG00000137710; HGNC ID: 9944
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst8 / 62319128
fetus33 / 56401258
neonate1 / 3109732
infant1 / 2362042
juvenile7 / 55556125
adult86 / 193912144
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor3 / 3436687
chondrosarcoma21 / 82823253
colorectal tumor0 / 1142460 
esophageal tumor1 / 1729057
gastrointestinal tumor4 / 11936933
germ cell tumor26 / 26384598
glioma6 / 10688356
head and neck tumor10 / 13630273
kidney tumor4 / 6895958
leukemia2 / 9584220
liver tumor4 / 9635941
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal202 / 336030760
ovarian tumor4 / 7668252
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer4 / 10268038
retinoblastoma1 / 4635621
skin tumor3 / 12494924
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland3 / 3319790
ascites1 / 4001524
bladder3 / 29757100
blood3 / 12347824
bone13 / 71655181
bone marrow3 / 4880161
brain106 / 110098996
cervix3 / 4817162
connective tissue14 / 14925593
ear0 / 162120 
embryonic tissue12 / 21572255
esophagus1 / 2020949
eye15 / 21105471
heart3 / 8962633
intestine3 / 23447212
kidney18 / 21177784
larynx0 / 241450 
liver10 / 20774348
lung11 / 33697432
lymph0 / 442700 
lymph node1 / 9161010
mammary gland3 / 15327119
mouth11 / 67052164
muscle10 / 10771592
nerve2 / 15768126
ovary6 / 10205158
pancreas5 / 21481223
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta12 / 28082542
prostate10 / 18934552
salivary gland1 / 2015549
skin6 / 21057428
spleen1 / 5395218
stomach1 / 9661910
testis22 / 33044266
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea9 / 52413171
umbilical cord0 / 136800 
uterus14 / 23287860
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212397_at
Cell line Expression level Expression bar
721_B_lymphoblasts340.5
Adipocyte93.9
AdrenalCortex491.95
Adrenalgland375.95
Amygdala240.8
Appendix67.15
AtrioventricularNode27.7
BDCA4+_DentriticCells26.45
Bonemarrow5.25
BronchialEpithelialCells203.25
CD105+_Endothelial129.6
CD14+_Monocytes46.25
CD19+_BCells(neg._sel.)25.9
CD33+_Myeloid37.75
CD34+70
CD4+_Tcells21.4
CD56+_NKCells18.85
CD71+_EarlyErythroid240.45
CD8+_Tcells16.85
CardiacMyocytes240.15
Caudatenucleus176.9
Cerebellum15.4
CerebellumPeduncles35.5
CiliaryGanglion24.4
CingulateCortex62.9
Colorectaladenocarcinoma63.45
DorsalRootGanglion43.3
FetalThyroid158.85
Fetalbrain114.9
Fetalliver224.25
Fetallung253.3
GlobusPallidus29.8
Heart7.8
Hypothalamus412.45
Kidney24.6
Leukemia_chronicMyelogenousK-562225.1
Leukemia_promyelocytic-HL-604.7
Leukemialymphoblastic(MOLT-4)27.6
Liver22.85
Lung22.1
Lymphnode57
Lymphoma_burkitts(Daudi)6.45
Lymphoma_burkitts(Raji)7.25
MedullaOblongata118.2
OccipitalLobe225.2
OlfactoryBulb218.85
Ovary23.35
Pancreas33.45
PancreaticIslet105.5
ParietalLobe172.1
Pituitary155.2
Placenta137.1
Pons48.9
PrefrontalCortex191.7
Prostate28.3
Salivarygland36.5
SkeletalMuscle33.85
Skin14.25
SmoothMuscle254.85
Spinalcord571.25
SubthalamicNucleus43.45
SuperiorCervicalGanglion16.1
TemporalLobe21.3
Testis18.6
TestisGermCell230.55
TestisIntersitial85.7
TestisLeydigCell60.8
TestisSeminiferousTubule57.35
Thalamus146.2
Thymus14.85
Thyroid272.3
Tongue58.65
Tonsil21.5
Trachea46.55
TrigeminalGanglion26.55
Uterus126.6
UterusCorpus19.8
WholeBlood21.1
Wholebrain82.65
colon44.55
pineal_day333.04
pineal_night348.66
retina256.85
small_intestine21.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14722_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.55 ± 0.56
Basal Forebrain8.88 ± 0.37
Basal Part of Pons8.41 ± 0.36
Cerebellar Cortex8.22 ± 0.26
Cerebellar Nuclei9.22 ± 0.48
Claustrum8.83 ± 0.43
Epithalamus8.83 ± 0.45
Frontal Lobe8.38 ± 0.52
Globus Pallidus9.82 ± 0.24
Hypothalamus8.51 ± 0.47
Insula8.28 ± 0.2
Limbic Lobe8.36 ± 0.56
Mesencephalon8.74 ± 0.35
Myelencephalon8.63 ± 0.42
Occipital Lobe8.73 ± 0.44
Parietal Lobe8.51 ± 0.5
Pontine Tegmentum8.67 ± 0.29
Striatum8.92 ± 0.54
Subthalamus8.83 ± 0.38
Temporal Lobe8.32 ± 0.41
Thalamus8.78 ± 0.34
White Matter10.41 ± 0.48
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
RdxCBCerebellum3.67
3.65
RdxCTXCerebral cortex6.31
3.01
RdxHIPHippocampal region6.72
5.08
RdxHPFHippocampal formation5.86
3.76
RdxHYHypothalamus4.71
1.59
RdxLSXLateral septal complex3.17
1.23
RdxMBMidbrain14.1
6.48
RdxMYMedulla25.24
14.45
RdxOLFOlfactory bulb9.3
4.32
RdxPPons17.49
9.81
RdxPALPallidum6.48
2.23
RdxRHPRetrohippocampal region4.19
1.78
RdxsAMYStriatum-like amygdalar nuclei2.71
1.11
RdxSTRStriatum2.26
1.07
RdxSTRdStriatum dorsal region2.53
1.32
RdxSTRvStriatum ventral region0.84
0.3
RdxTHThalamus7.67
2.96
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00004175 11 263 273 KAPDFVFYAPR Peptide Atlas
RADI_HUMAN_172 9 172 180 IQNWHEEHR PRIDE
RADI_HUMAN_237 9 237 245 IGFPWSEIR PRIDE
RADI_HUMAN_262 11 262 272 KAPDFVFYAPR PRIDE
RADI_HUMAN_263 10 263 272 APDFVFYAPR PRIDE
RADI_HUMAN_279 14 279 292 ILALCMGNHELYMR PRIDE
RADI_HUMAN_83 17 83 99 FFPEDVSEELIQEITQR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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