AutismKB 2.0

Annotation Detail for BCL2A1


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Basic Information Top
Gene Symbol:BCL2A1 ( ACC-1,ACC-2,BCL2L5,BFL1,GRS,HBPA1 )
Gene Full Name: BCL2-related protein A1
Band: 15q25.1
Quick LinksEntrez ID:597; OMIM: 601056; Uniprot ID:B2LA1_HUMAN; ENSEMBL ID: ENSG00000140379; HGNC ID: 991
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus1 / 5640121
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult26 / 193912113
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia3 / 9584231
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma2 / 7175527
non-neoplasia0 / 972500 
normal27 / 33603078
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor5 / 12494940
soft tissue/muscle tissue tumor13 / 125191103
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood11 / 12347889
bone0 / 716550 
bone marrow1 / 4880120
brain0 / 11009890 
cervix0 / 481710 
connective tissue13 / 14925587
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart1 / 8962611
intestine2 / 2344728
kidney4 / 21177718
larynx0 / 241450 
liver2 / 2077439
lung0 / 3369740 
lymph0 / 442700 
lymph node8 / 9161087
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate1 / 1893455
salivary gland0 / 201550 
skin6 / 21057428
spleen0 / 539520 
stomach5 / 9661951
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205681_at
Cell line Expression level Expression bar
721_B_lymphoblasts625.05
Adipocyte7.7
AdrenalCortex9.45
Adrenalgland7.4
Amygdala7.9
Appendix10.85
AtrioventricularNode11.6
BDCA4+_DentriticCells63.6
Bonemarrow134.9
BronchialEpithelialCells7.55
CD105+_Endothelial8.3
CD14+_Monocytes591.05
CD19+_BCells(neg._sel.)80.15
CD33+_Myeloid418.5
CD34+9.35
CD4+_Tcells55.1
CD56+_NKCells265.6
CD71+_EarlyErythroid7.8
CD8+_Tcells15.3
CardiacMyocytes14.55
Caudatenucleus7.35
Cerebellum6.85
CerebellumPeduncles10
CiliaryGanglion9.35
CingulateCortex8.5
Colorectaladenocarcinoma7.9
DorsalRootGanglion8.7
FetalThyroid8.25
Fetalbrain7.55
Fetalliver7.2
Fetallung49.45
GlobusPallidus7.05
Heart13.8
Hypothalamus8.1
Kidney7.55
Leukemia_chronicMyelogenousK-5626.8
Leukemia_promyelocytic-HL-60111.55
Leukemialymphoblastic(MOLT-4)5.95
Liver12.4
Lung17.95
Lymphnode55.15
Lymphoma_burkitts(Daudi)10.85
Lymphoma_burkitts(Raji)113.85
MedullaOblongata7.15
OccipitalLobe7
OlfactoryBulb6.5
Ovary7.35
Pancreas7.95
PancreaticIslet9
ParietalLobe9.4
Pituitary9.5
Placenta7.6
Pons8.75
PrefrontalCortex9.05
Prostate8.75
Salivarygland7.2
SkeletalMuscle12.1
Skin10.05
SmoothMuscle8.95
Spinalcord8.65
SubthalamicNucleus8.05
SuperiorCervicalGanglion17.9
TemporalLobe7.9
Testis6.75
TestisGermCell6.25
TestisIntersitial7.05
TestisLeydigCell12.35
TestisSeminiferousTubule7.3
Thalamus8.6
Thymus6.55
Thyroid8.55
Tongue9.35
Tonsil77.45
Trachea7.2
TrigeminalGanglion15.55
Uterus6.15
UterusCorpus9.95
WholeBlood1071.35
Wholebrain6.3
colon7.8
pineal_day9.58
pineal_night9.02
retina9.65
small_intestine7.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P152002
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.19 ± 0.94
Basal Forebrain1.73 ± 0.2
Basal Part of Pons1.41 ± 0.31
Cerebellar Cortex1.49 ± 0.57
Cerebellar Nuclei1.98 ± 0.69
Claustrum2.59 ± 0.85
Epithalamus1.7 ± 0.87
Frontal Lobe1.51 ± 0.52
Globus Pallidus2.65 ± 0.55
Hypothalamus1.77 ± 0.69
Insula1.59 ± 0.45
Limbic Lobe1.75 ± 0.71
Mesencephalon1.85 ± 0.64
Myelencephalon1.75 ± 0.63
Occipital Lobe1.82 ± 0.58
Parietal Lobe1.71 ± 0.62
Pontine Tegmentum1.74 ± 0.63
Striatum1.84 ± 0.44
Subthalamus1.86 ± 0.63
Temporal Lobe1.62 ± 0.59
Thalamus1.67 ± 0.54
White Matter2.52 ± 0.98
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Bcl2a1aCBCerebellum1.67
2.33
Bcl2a1aCTXCerebral cortex0.5
0.68
Bcl2a1aHIPHippocampal region0.43
0.42
Bcl2a1aHPFHippocampal formation0.41
0.43
Bcl2a1aHYHypothalamus0.2
0.2
Bcl2a1aLSXLateral septal complex0.37
0.31
Bcl2a1aMBMidbrain0.24
0.32
Bcl2a1aMYMedulla1.15
1.61
Bcl2a1aOLFOlfactory bulb2.25
1.76
Bcl2a1aPPons0.42
0.65
Bcl2a1aPALPallidum0.34
0.39
Bcl2a1aRHPRetrohippocampal region0.35
0.43
Bcl2a1asAMYStriatum-like amygdalar nuclei0.23
0.24
Bcl2a1aSTRStriatum0.31
0.37
Bcl2a1aSTRdStriatum dorsal region0.31
0.44
Bcl2a1aSTRvStriatum ventral region0.34
0.33
Bcl2a1aTHThalamus0.21
0.29
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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