AutismKB 2.0

Annotation Detail for DPF2


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Basic Information Top
Gene Symbol:DPF2 ( MGC10180,REQ,UBID4,ubi-d4 )
Gene Full Name: D4, zinc and double PHD fingers family 2
Band: 11q13.1
Quick LinksEntrez ID:5977; OMIM: 601671; Uniprot ID:REQU_HUMAN; ENSEMBL ID: ENSG00000133884; HGNC ID: 9964
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body9 / 70761127
blastocyst8 / 62319128
fetus42 / 56401274
neonate1 / 3109732
infant0 / 236200 
juvenile11 / 55556197
adult136 / 193912170
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma4 / 17475228
breast (mammary gland) tumor16 / 94178169
cervical tumor2 / 3436658
chondrosarcoma5 / 8282360
colorectal tumor10 / 11424687
esophageal tumor2 / 17290115
gastrointestinal tumor4 / 11936933
germ cell tumor29 / 263845109
glioma18 / 106883168
head and neck tumor17 / 136302124
kidney tumor8 / 68959116
leukemia13 / 95842135
liver tumor5 / 9635951
lung tumor7 / 10312767
lymphoma10 / 71755139
non-neoplasia4 / 9725041
normal233 / 336030769
ovarian tumor7 / 7668291
pancreatic tumor12 / 104616114
primitive neuroectodermal tumor of the CNS15 / 125680119
prostate cancer7 / 10268068
retinoblastoma4 / 4635686
skin tumor4 / 12494932
soft tissue/muscle tissue tumor12 / 12519195
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland3 / 3319790
ascites2 / 4001549
bladder4 / 29757134
blood8 / 12347864
bone8 / 71655111
bone marrow2 / 4880140
brain81 / 110098973
cervix6 / 48171124
connective tissue8 / 14925553
ear0 / 162120 
embryonic tissue22 / 215722101
esophagus2 / 2020998
eye12 / 21105456
heart7 / 8962678
intestine19 / 23447281
kidney14 / 21177766
larynx5 / 24145207
liver9 / 20774343
lung23 / 33697468
lymph4 / 4427090
lymph node13 / 91610141
mammary gland22 / 153271143
mouth6 / 6705289
muscle6 / 10771555
nerve0 / 157680 
ovary9 / 10205188
pancreas15 / 21481269
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland2 / 16585120
placenta21 / 28082574
prostate15 / 18934579
salivary gland4 / 20155198
skin9 / 21057442
spleen1 / 5395218
stomach0 / 966190 
testis20 / 33044260
thymus11 / 81131135
thyroid8 / 47473168
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus25 / 232878107
vascular7 / 51780135
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202116_at
Cell line Expression level Expression bar
721_B_lymphoblasts61.6
Adipocyte10.9
AdrenalCortex11.3
Adrenalgland9.5
Amygdala9.7
Appendix11.05
AtrioventricularNode8.25
BDCA4+_DentriticCells62.5
Bonemarrow10.85
BronchialEpithelialCells11.1
CD105+_Endothelial21.45
CD14+_Monocytes25.5
CD19+_BCells(neg._sel.)53.1
CD33+_Myeloid29.2
CD34+92.65
CD4+_Tcells39.25
CD56+_NKCells76.45
CD71+_EarlyErythroid11.75
CD8+_Tcells18.4
CardiacMyocytes11.95
Caudatenucleus10.45
Cerebellum10.85
CerebellumPeduncles12.7
CiliaryGanglion7.75
CingulateCortex11.15
Colorectaladenocarcinoma11.2
DorsalRootGanglion8.35
FetalThyroid13.55
Fetalbrain13.1
Fetalliver7.3
Fetallung10.1
GlobusPallidus8.15
Heart15.95
Hypothalamus13.7
Kidney8.9
Leukemia_chronicMyelogenousK-56216.6
Leukemia_promyelocytic-HL-609.9
Leukemialymphoblastic(MOLT-4)25.1
Liver14.5
Lung20.75
Lymphnode9.85
Lymphoma_burkitts(Daudi)17.85
Lymphoma_burkitts(Raji)9.85
MedullaOblongata10.7
OccipitalLobe10
OlfactoryBulb10.05
Ovary7.35
Pancreas8.75
PancreaticIslet13.2
ParietalLobe11.8
Pituitary13
Placenta13.35
Pons10.75
PrefrontalCortex29.45
Prostate13.3
Salivarygland8.9
SkeletalMuscle12.55
Skin8.15
SmoothMuscle15.2
Spinalcord12.35
SubthalamicNucleus9.75
SuperiorCervicalGanglion10.4
TemporalLobe10.1
Testis34.5
TestisGermCell20.05
TestisIntersitial15.25
TestisLeydigCell11.05
TestisSeminiferousTubule20.35
Thalamus11.15
Thymus21.4
Thyroid13
Tongue8.95
Tonsil11.05
Trachea8.4
TrigeminalGanglion8.45
Uterus9.7
UterusCorpus11.25
WholeBlood45.5
Wholebrain15.05
colon11.05
pineal_day47.92
pineal_night32.48
retina13.85
small_intestine11.4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1364_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.92 ± 0.32
Basal Forebrain5.26 ± 0.38
Basal Part of Pons4.74 ± 0.5
Cerebellar Cortex4.86 ± 0.33
Cerebellar Nuclei5.17 ± 0.62
Claustrum4.9 ± 0.72
Epithalamus5.45 ± 0.19
Frontal Lobe4.67 ± 0.53
Globus Pallidus5.64 ± 0.42
Hypothalamus4.7 ± 0.39
Insula4.64 ± 0.45
Limbic Lobe4.89 ± 0.47
Mesencephalon5.08 ± 0.47
Myelencephalon4.99 ± 0.45
Occipital Lobe5.18 ± 0.44
Parietal Lobe4.93 ± 0.41
Pontine Tegmentum4.94 ± 0.43
Striatum5.3 ± 0.41
Subthalamus4.86 ± 0.6
Temporal Lobe4.8 ± 0.42
Thalamus5.04 ± 0.4
White Matter6.41 ± 0.36
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Dpf2CBCerebellum30.37
28.79
Dpf2CTXCerebral cortex58.56
27.74
Dpf2HIPHippocampal region41.43
31.86
Dpf2HPFHippocampal formation56.76
37.33
Dpf2HYHypothalamus29.06
15.83
Dpf2LSXLateral septal complex9.33
4.05
Dpf2MBMidbrain23.55
13.44
Dpf2MYMedulla47.09
36
Dpf2OLFOlfactory bulb72.48
44.55
Dpf2PPons40.07
31.72
Dpf2PALPallidum36.63
22.89
Dpf2RHPRetrohippocampal region90.78
49.25
Dpf2sAMYStriatum-like amygdalar nuclei57.25
27.25
Dpf2STRStriatum47.33
22
Dpf2STRdStriatum dorsal region52.89
23.71
Dpf2STRvStriatum ventral region44.38
23.68
Dpf2THThalamus22.14
11.29
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00005093 20 11 30 LLGEQYYKDAMEQCHNYNAR Peptide Atlas
REQU_HUMAN_127 5 127 131 PLEKR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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