AutismKB 2.0

Annotation Detail for RGS2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:RGS2 ( G0S8 )
Gene Full Name: regulator of G-protein signaling 2, 24kDa
Band: 1q31.2
Quick LinksEntrez ID:5997; OMIM: 600861; Uniprot ID:RGS2_HUMAN; ENSEMBL ID: ENSG00000116741; HGNC ID: 9998
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst0 / 623190 
fetus21 / 56401237
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult181 / 193912193
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor8 / 9417884
cervical tumor0 / 343660 
chondrosarcoma9 / 82823108
colorectal tumor3 / 11424626
esophageal tumor2 / 17290115
gastrointestinal tumor7 / 11936958
germ cell tumor18 / 26384568
glioma3 / 10688328
head and neck tumor3 / 13630222
kidney tumor3 / 6895943
leukemia18 / 95842187
liver tumor0 / 963590 
lung tumor5 / 10312748
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal242 / 336030772
ovarian tumor1 / 7668213
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor10 / 12519179
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland1 / 3319730
ascites1 / 4001524
bladder1 / 2975733
blood39 / 123478315
bone1 / 7165513
bone marrow9 / 48801184
brain28 / 110098925
cervix0 / 481710 
connective tissue9 / 14925560
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus2 / 2020998
eye34 / 211054161
heart8 / 8962689
intestine14 / 23447259
kidney21 / 21177799
larynx0 / 241450 
liver7 / 20774333
lung26 / 33697477
lymph0 / 442700 
lymph node4 / 9161043
mammary gland9 / 15327158
mouth1 / 6705214
muscle1 / 1077159
nerve1 / 1576863
ovary4 / 10205139
pancreas28 / 214812130
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland2 / 16585120
placenta14 / 28082549
prostate20 / 189345105
salivary gland0 / 201550 
skin3 / 21057414
spleen3 / 5395255
stomach7 / 9661972
testis8 / 33044224
thymus2 / 8113124
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus21 / 23287890
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202388_at
Cell line Expression level Expression bar
721_B_lymphoblasts10.8
Adipocyte16.15
AdrenalCortex1558.3
Adrenalgland236.1
Amygdala92.65
Appendix228.75
AtrioventricularNode25.5
BDCA4+_DentriticCells3148.15
Bonemarrow475.65
BronchialEpithelialCells320.45
CD105+_Endothelial429.8
CD14+_Monocytes7311.65
CD19+_BCells(neg._sel.)596.95
CD33+_Myeloid7924.9
CD34+389.1
CD4+_Tcells175.85
CD56+_NKCells1988.5
CD71+_EarlyErythroid23.55
CD8+_Tcells186.9
CardiacMyocytes15.55
Caudatenucleus166.85
Cerebellum6.45
CerebellumPeduncles18.2
CiliaryGanglion38.1
CingulateCortex61.7
Colorectaladenocarcinoma6.65
DorsalRootGanglion30.05
FetalThyroid6.4
Fetalbrain62.9
Fetalliver8
Fetallung305.7
GlobusPallidus8.8
Heart10.1
Hypothalamus149.8
Kidney12
Leukemia_chronicMyelogenousK-5627.3
Leukemia_promyelocytic-HL-6011
Leukemialymphoblastic(MOLT-4)8.35
Liver9.3
Lung65.75
Lymphnode111.8
Lymphoma_burkitts(Daudi)13.7
Lymphoma_burkitts(Raji)17.75
MedullaOblongata86.95
OccipitalLobe39.15
OlfactoryBulb333.05
Ovary156.35
Pancreas318.35
PancreaticIslet800.5
ParietalLobe38.25
Pituitary608.35
Placenta53.05
Pons46.45
PrefrontalCortex96
Prostate239.05
Salivarygland51.65
SkeletalMuscle11.2
Skin24.95
SmoothMuscle34.65
Spinalcord137.1
SubthalamicNucleus34.05
SuperiorCervicalGanglion25.2
TemporalLobe41.45
Testis17.65
TestisGermCell152.45
TestisIntersitial29.9
TestisLeydigCell104.45
TestisSeminiferousTubule22.9
Thalamus68.7
Thymus24.8
Thyroid33.6
Tongue12.65
Tonsil20.9
Trachea74.8
TrigeminalGanglion22.55
Uterus1344.45
UterusCorpus192.95
WholeBlood7046.05
Wholebrain67.35
colon156.95
pineal_day150.98
pineal_night75.5
retina778.75
small_intestine185
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15741_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.32 ± 0.58
Basal Forebrain6.22 ± 0.37
Basal Part of Pons6.12 ± 0.42
Cerebellar Cortex5.93 ± 0.3
Cerebellar Nuclei6.77 ± 0.61
Claustrum5.89 ± 0.69
Epithalamus6.3 ± 0.73
Frontal Lobe6.3 ± 0.47
Globus Pallidus6.43 ± 0.33
Hypothalamus6.6 ± 0.76
Insula6.39 ± 0.29
Limbic Lobe6.72 ± 0.44
Mesencephalon6.6 ± 0.78
Myelencephalon6.44 ± 0.59
Occipital Lobe6.9 ± 0.56
Parietal Lobe6.39 ± 0.43
Pontine Tegmentum6.66 ± 0.47
Striatum7.98 ± 0.56
Subthalamus6.2 ± 0.5
Temporal Lobe6.23 ± 0.37
Thalamus6.35 ± 0.41
White Matter5.59 ± 0.04
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rgs2CBCerebellum0.78
1.46
Rgs2CTXCerebral cortex2.94
2.21
Rgs2HIPHippocampal region1.4
1.45
Rgs2HPFHippocampal formation1.69
1.57
Rgs2HYHypothalamus2.43
2.12
Rgs2LSXLateral septal complex15.63
13.71
Rgs2MBMidbrain1.93
2.07
Rgs2MYMedulla2.67
3.33
Rgs2OLFOlfactory bulb3.01
2.29
Rgs2PPons1.99
2.52
Rgs2PALPallidum3.62
3.3
Rgs2RHPRetrohippocampal region2.28
1.82
Rgs2sAMYStriatum-like amygdalar nuclei4.11
3.47
Rgs2STRStriatum19.19
14.96
Rgs2STRdStriatum dorsal region22.67
17.76
Rgs2STRvStriatum ventral region18.33
13.25
Rgs2THThalamus1.73
1.8
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved